Notes to mathematical and physical modelling of inhalation process in the “inhalator-airways” system

Abstract

Questions about the inhalation devices constructing that allow to spray optimally the inhaled powders with minimal sedimentation in upper airways were discussed in this article. To solve successfully the problem of optimal medication delivery into distal bronchi, the experimental device modelling the “ inhaler-airways” system and fitting to conditions of airflow in airways and to imaginations about respiratory system functioning was designed. During constructing the device and result analysis, the authors used the mathematical model of respiratory system, that is presented in the article.
The use of the device allowed to estimate objectively the advantage of the native dry inhaler IN-2 in comparison with foreign analogues. The designed measures of mathematical and physical modelling allow to estimate the efficiency of the most used dry inhalers, that is very important for decisions of the foreign analogues buying.