A comparison of airway microbiota in donors and recipients of lung transplants
https://doi.org/10.18093/0869-0189-2019-29-2-184-188
Abstract
This study was aimed at investigation of relationships between bronchial washing culture in post-transplant recipient and bronchial flora of the lung donor. Methods. A comparative analysis of bronchial washing cultures from 30 post-transplant lung recipients was performed. All lung donors were stratified to ideal, suboptimal and marginal donors according to the lung transplant suitability. Results. As a result, development of post-transplant pulmonary complications was directly related to bacterial flora of the donor lung. The incidence of pneumonia in post-transplant patients was 3.3% after transplantation of ideal donor lungs, 20% after transplantation of suboptimal donors lungs and 100% after transplantation of marginal donor lungs. Conclusion. The rate of pneumonia in transplanted lungs was directly related to bronchial flora in the donor lungs. This should be taken into account when planning antibacterial therapy after lung transplantation.
About the Authors
M. Sh. Khubutiya
N.V.Sklifosovskiy State Research Institute of Emergency Care, Moscow Healthcare Department
Russian Federation
Russian Federation
Mogeli Sh. Khubutiya, Doctor of Medicine, Professor, Corresponding Member of Russian Academy of Science, President of N.V.Sklifosovskiy State Research Institute of Emergency Care, Moscow Healthcare Department; tel.: (495) 625-38-97;
Bol. Sukharevskaya pl. 3, Moscow, 129090
A. M. Gasanov
N.V.Sklifosovskiy State Research Institute of Emergency Care, Moscow Healthcare Department
Russian Federation
Russian Federation
Ali M. Gasanov, Candidate of Medicine, Senior Researcher, Department of Emergency Endoscopy, N.V.Sklifosovskiy State Research Institute of Emergency Care, Moscow Healthcare Department; tel.: (926) 266-47-46;
Bol. Sukharevskaya pl. 3, Moscow, 129090
E. A. Tarabrin
N.V.Sklifosovskiy State Research Institute of Emergency Care, Moscow Healthcare Department
Russian Federation
Russian Federation
Evgeniy A. Tarabrin, Candidate of Medicine, Head of Research Department of Thoracic Surgery, N.V.Sklifosovskiy State Research Institute of Emergency Care, Moscow Healthcare Department; tel.: (910) 439-30-21;
Bol. Sukharevskaya pl. 3, Moscow, 129090
T. V. Chernen’kaya
N.V.Sklifosovskiy State Research Institute of Emergency Care, Moscow Healthcare Department
Russian Federation
Russian Federation
Tat’yana V. Chernen’kaya, Candidate of Medicine, Head of Research Laboratory of Clinical Microbiology, N.V.Sklifosovskiy State Research Institute of Emergency Care, Moscow Healthcare Department; tel.: (495) 680-41-54;
Bol. Sukharevskaya pl. 3, Moscow, 129090
T. E. Kallagov
N.V.Sklifosovskiy State Research Institute of Emergency Care, Moscow Healthcare Department
Russian Federation
Russian Federation
Taymuraz E. Kallagov, Researcher, Department of Urgent Thoracoabdominal Surgery, N.V.Sklifosovskiy State Research Institute of Emergency Care, Moscow Healthcare Department; tel.: (495) 680 41-54;
Bol. Sukharevskaya pl. 3, Moscow, 129090
E. I. Pervakova
N.V.Sklifosovskiy State Research Institute of Emergency Care, Moscow Healthcare Department
Russian Federation
Russian Federation
El’za I. Pervakova, Candidate of Medicine, Head of Research Department of resuscitation, N.V.Sklifosovskiy State Research Institute of Emergency Care, Moscow Healthcare Department; tel.: (495) 680-41-54;
Bol. Sukharevskaya pl. 3, Moscow, 129090
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Review
For citations:
Khubutiya M.Sh., Gasanov A.M., Tarabrin E.A., Chernen’kaya T.V., Kallagov T.E., Pervakova E.I. A comparison of airway microbiota in donors and recipients of lung transplants. PULMONOLOGIYA. 2019;29(2):184-188. (In Russ.) https://doi.org/10.18093/0869-0189-2019-29-2-184-188
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