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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pulmo</journal-id><journal-title-group><journal-title xml:lang="ru">Пульмонология</journal-title><trans-title-group xml:lang="en"><trans-title>PULMONOLOGIYA</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-0189</issn><issn pub-type="epub">2541-9617</issn><publisher><publisher-name>Scientific and Practical Journal “PULMONOLOGIYA” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18093/0869-0189-2016-26-4-505-513</article-id><article-id custom-type="elpub" pub-id-type="custom">pulmo-752</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ ФАРМАКОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL PHARMACOLOGY</subject></subj-group></article-categories><title-group><article-title>Место фиксированной комбинации бронходилататоров длительного действия тиотропий / олодатерол в стартовой терапии хронической обструктивной болезни легких. Заключение Совета экспертов Российского респираторного общества</article-title><trans-title-group xml:lang="en"><trans-title>A role of long-acting bronchodilator tiotropium / olodaterol fixed combination as the first-line therapy of chronic obstructive pulmonary disease. A Consensus of Expert Board of Russian Respiratory Society</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Авдеев</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Avdeev</surname><given-names>S. N.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Айсанов</surname><given-names>З. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Aisanov</surname><given-names>Z. R.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белевский</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Belevskiy</surname><given-names>A. S.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зыков</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zykov</surname><given-names>K. A.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лещенко</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Leshchenko</surname><given-names>I. V.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Овчаренко</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Ovcharenko</surname><given-names>S. I.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шмелев</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Shmelev</surname><given-names>E. I.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Архипов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Arkhipov</surname><given-names>V. V.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горблянский</surname><given-names>Ю. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Gorblyanskiy</surname><given-names>Yu. Yu.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Емельянов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Emel'yanov</surname><given-names>A. V.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Игнатова</surname><given-names>Г. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Ignatova</surname><given-names>G. L.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Казанцев</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kazantsev</surname><given-names>V. A.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кароли</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Karoli</surname><given-names>N. A.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колбасников</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kolbasnikov</surname><given-names>S. V.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Куделя</surname><given-names>Л. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kudelya</surname><given-names>L. M.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузубова</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuzubova</surname><given-names>N. A.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синопальников</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Sinopal'nikov</surname><given-names>A. I.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Степанян</surname><given-names>И. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Stepanyan</surname><given-names>I. E.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трофименко</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Trofimenko</surname><given-names>I. N.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фассахов</surname><given-names>Р. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Fassakhov</surname><given-names>R. S.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хамитов</surname><given-names>Р. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Khamitov</surname><given-names>R. F.</given-names></name></name-alternatives></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шапорова</surname><given-names>Н. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Shaporova</surname><given-names>N. L.</given-names></name></name-alternatives></contrib></contrib-group><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>18</day><month>10</month><year>2016</year></pub-date><volume>26</volume><issue>4</issue><fpage>505</fpage><lpage>513</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Авдеев С.Н., Айсанов З.Р., Белевский А.С., Зыков К.А., Лещенко И.В., Овчаренко С.И., Шмелев Е.И., Архипов В.В., Горблянский Ю.Ю., Емельянов А.В., Игнатова Г.Л., Казанцев В.А., Кароли Н.А., Колбасников С.В., Куделя Л.М., Кузубова Н.А., Синопальников А.И., Степанян И.Э., Трофименко И.Н., Фассахов Р.С., Хамитов Р.Ф., Шапорова Н.Л., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Авдеев С.Н., Айсанов З.Р., Белевский А.С., Зыков К.А., Лещенко И.В., Овчаренко С.И., Шмелев Е.И., Архипов В.В., Горблянский Ю.Ю., Емельянов А.В., Игнатова Г.Л., Казанцев В.А., Кароли Н.А., Колбасников С.В., Куделя Л.М., Кузубова Н.А., Синопальников А.И., Степанян И.Э., Трофименко И.Н., Фассахов Р.С., Хамитов Р.Ф., Шапорова Н.Л.</copyright-holder><copyright-holder xml:lang="en">Avdeev S.N., Aisanov Z.R., Belevskiy A.S., Zykov K.A., Leshchenko I.V., Ovcharenko S.I., Shmelev E.I., Arkhipov V.V., Gorblyanskiy Y.Y., Emel'yanov A.V., Ignatova G.L., Kazantsev V.A., Karoli N.A., Kolbasnikov S.V., Kudelya L.M., Kuzubova N.A., Sinopal'nikov A.I., Stepanyan I.E., Trofimenko I.N., Fassakhov R.S., Khamitov R.F., Shaporova N.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.pulmonology.ru/pulm/article/view/752">https://journal.pulmonology.ru/pulm/article/view/752</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Global Initiative for Chronic Obstructive Lung Disease (GOLD). 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