pulmoПульмонологияPULMONOLOGIYA0869-01892541-9617Scientific and Practical Journal “PULMONOLOGIYA” LLC10.18093/0869-0189-2016-26-3-364-371pulmo-729Research ArticleОБЗОРЫREVIEWКоморбидность хронической обструктивной болезни легких и сердечно6сосудистой патологии: особенности леченияTreatment of comorbid chronic obstructive pulmonary disease and cardiovascular diseaseВатутинН. Т.VatutinN. T.

д. м. н., профессор, зав. кафедрой госпитальной терапии ГО «Донецкий национальный медицинский университет им. М.Горького», и. о. зав. отделом неотложной и восстановительной кардиохирургии ГУ «Институт неотложной и восстановительной хирургии им. В.К.Гусака НАМН Украины»; тел.: (38062) 3850517

MD, Professor, Head of Department of Hospital Internal Medicine, M.Gor'kiy Donetsk National Medical University; Alternate Head of Division of Urgent and Reconstructive Cardiosurgery, V.K.Gusak’ State Institute of Urgent and Reconstructive Surgery; National Medical Science Academy of Ukraine; tel.: (38062) 3850517

kafedra_vatutin@mail.ruСмирноваА. С.SmirnovaA. S.

к. м. н., ассистент кафедры госпитальной терапии ГО «Донецкий национальный медицинский университет им. М.Горького»; тел.: (38062) 3850517

PhD, Assistant Lecturer at Department of Hospital Internal Medicine, M.Gor'kiy Donetsk National Medical University; tel.: (38062) 3850517

a.smyrnova@mail.ruДонецкий национальный медицинский университет им. М.Горького: 83005, Украина, Донецк, пр. Ильича, 14 ГУ «Институт неотложной и восстановительной хирургии им. В.К.Гусака НАМН Украины»: 83000, Украина, Донецк, Ленинский проспект, 47РоссияM.Gor'kiy Donetsk National State Medical University: 14, Il'icha av., Donetsk ,83005, Ukraine V.K.Gusak State Institute of Urgent and Reconstructive Surgery, National Medical Science Academy of Ukraine: 47, Leninskiy av., Donetsk, 83000, UkraineRussian FederationДонецкий национальный медицинский университет им. М.Горького: 83005, Украина, Донецк, пр. Ильича, 14РоссияM.Gor'kiy Donetsk National State Medical University: 14, Il'icha av., Donetsk ,83005, UkraineRussian Federation201627072016263364371Copyright © Ватутин Н.Т., Смирнова А.С., 20162016Ватутин Н.Т., Смирнова А.С.Vatutin N.T., Smirnova A.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.pulmonology.ru/pulm/article/view/729

При кардиореспираторной коморбидности, сопровождающейся синдромом взаимного отягощения, формируются определенные особенности клинической картины ввиду общности некоторых звеньев патогенеза, что приводит к снижению эффекта лечения, ухудшению прогноза заболеваний и требует новых подходов к диагностике и лечению. При выборе тактики ведения больных хронической обструктивной болезнью легких (ХОБЛ) и сопутствующей кардиальной патологией необходимо помнить о суммарном риске. Известно, что некоторые препараты, традиционно используемые в лечении сердечно"сосудистых заболеваний, отрицательно влияют на течение ХОБЛ, а бронхолитические препараты, без которых трудно представить лечение обструктивного бронхита, могут оказывать неблагоприятное действие на кардиоваскулярную систему. Поэтому выбор лекарственных средств, применяемых в лечении кардиальной патологии, может быть чрезвычайно ограничен при наличии сопутствующей ХОБЛ. В данном обзоре предоставлены современные сведения, касающиеся особенностей лечения больных с коморбидной патологией.

This review provided recent information about treatment of patients with comorbid respiratory and cardiovascular disease. Cardiorespiratory comorbidity is associated with cross"deterioration of the disease course given similar pathogenic components. This could decrease effects of treatment, worsen prognosis and actually requires new approaches to diagnosis and therapy. While choosing the treatment strategy for a patient with comorbid chronic obstructive pulmonary disease (COPD) and cardiovascular disease, a physician should be aware of the pooled risk of adverse events. Some agents widely used for treatment of cardiovascular diseases could worsen the course of COPD and, vice versa, bronchodilators that are the essential component of therapy of chronic obstructive bronchitis could adversely affect the cardiovascular system. Therefore, medication choice could be significantly limited due to comorbidity.

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The authors declare that there are no conflicts of interest present.