pulmoПульмонологияPULMONOLOGIYA0869-01892541-9617Scientific and Practical Journal “PULMONOLOGIYA” LLC10.18093/0869-0189-2015-25-2-224-228pulmo-561Research ArticleОБЗОРЫREVIEWСиндром кашлевой гиперчувствительностиChronic cough hypersensitivity syndromeЧикинаС. Ю.ChikinaS. Yu.

к. м. н., ст. научный сотрудник лаборатории функциональных и ультразвуковых методов исследования ФГБУ «НИИ пульмонологии» ФМБА России; тел.: (495) 465-53-84;

PhD, Senior Researcher of Laboratory of Functional and Ultrasound Investigations, Federal Institution "Pulmonology Research Institute", Federal Medical and Biological Agency of Russia, tel.: (495) 465

svch@list.ruФГБУ «НИИ пульмонологии» ФМБА России: 105077, Москва, ул. 11-я Парковая, 32, корп. 4РоссияFederal Institution «Pulmonology Research Institute», Federal Medical and Biological Agency of Russia; 32, build. 4, 11th Parkovaya ul., Moscow, 105077, RussiaRussian Federation201524062015252224228Copyright © Чикина С.Ю., 20152015Чикина С.Ю.Chikina S.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.pulmonology.ru/pulm/article/view/561

Приводится описание новой теории патогенеза хронического кашля (ХК). В последние годы открыты специфические кашлевые рецепторы и доказана ключевая роль изменения их чувствительности в развитии ХК. На основе полученных данных сформулирована патогенетическая концепция ХК как самостоятельного заболевания. Показаны гендерные и возрастные различия в распространенности ХК и чувствительности кашлевых рецепторов.

This article contains a review of a new concept of chronic cough. Recently, specific TRP receptors were investigated and the key role of increased sensitivity of these receptors for chronic cough development was described. Recent scientific data underlay a pathogenic concept of chronic cough as an independent pathological entity referred to as chronic cough hypersensitivity syndrome. Gender and age-related difference in pathogenesis and prevalence of chronic cough and cough receptor hypersensitivity have also reviewed in the article.

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The authors declare that there are no conflicts of interest present.