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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pulmo</journal-id><journal-title-group><journal-title xml:lang="ru">Пульмонология</journal-title><trans-title-group xml:lang="en"><trans-title>PULMONOLOGIYA</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-0189</issn><issn pub-type="epub">2541-9617</issn><publisher><publisher-name>Scientific and Practical Journal “PULMONOLOGIYA” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18093/0869-0189-2025-35-4-553-560</article-id><article-id custom-type="elpub" pub-id-type="custom">pulmo-4793</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Киста Хаттори: обзор литературы и презентация случая</article-title><trans-title-group xml:lang="en"><trans-title>Cyst of Hattori: literature review and case presentation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0537-025X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бердников</surname><given-names>Р. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Berdnikov</surname><given-names>R. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бердников Роман Борисович – к. м. н., врач-патологоанатом патологоанатомического отделения Уральского научно-исследовательского института фтизиопульмонологии; доцент кафедры патологической анатомии и судебной медицины  Уральского государственного медицинского университета</p><p>620039, Екатеринбург, ул. 22-го Партсъезда, 5; 620028, Екатеринбург, ул. Репина, 3</p><p> </p></bio><bio xml:lang="en"><p>Roman B. Berdnikov, Candidate of Medicine, Pathologist, Pathological Anatomy Department, Ural Federal Research Institute of Phthisiology and Pulmonology; Associate Professor, Department of Pathological Anatomy and Forensic Medicine, Ural State Medical University</p><p>ul. 22-go Parts’ezda 50, Ekaterinburg, 620039; ul. 22-go Parts’ezda 50, Ekaterinburg, 620039</p><p> </p></bio><email xlink:type="simple">rberdnikov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Андрющенко</surname><given-names>К. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Andryuschenko</surname><given-names>K. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Андрющенко Кирилл Юрьевич – врач-патологоанатом патологоанатомического отделения Уральского научно-исследовательского института фтизиопульмонологии; врач-патологоанатом патологоанатомического отделения, Областной клинический медицинский центр фтизиопульмонологии и инфекционных заболеваний</p><p>620039, Екатеринбург, ул. 22-го Партсъезда, 5; 620030, Екатеринбург, ул. Дублер Сибирского тракта, 56</p></bio><bio xml:lang="en"><p>Kirill Yu. Andryuschenko, Pathologist, Pathological Anatomy Department, Ural Federal Research Institute of Phthisiology and Pulmonology; Pathologist, Pathological Anatomy Department, Regional clinical medical center of phthisiopulmonology and infectional diseases</p><p>ul. 22-go Parts’ezda 50, Ekaterinburg, 620039; ul. Dublyor Sibirskogo trakta 56, Ekaterinburg, 620030</p></bio><email xlink:type="simple">derp64705@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Заваров</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Zavarov</surname><given-names>N. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Заваров Николай Сергеевич – врач-патологоанатом патологоанатомического отделения </p><p>620030, Екатеринбург, ул. Дублер Сибирского тракта, 56</p></bio><bio xml:lang="en"><p>Nikolay S. Zavarov, Pathologist, Pathological Anatomy Department</p><p>ul. 22-go Parts’ezda 50, Ekaterinburg, 620039</p></bio><email xlink:type="simple">zavarovnikolay@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петрунина</surname><given-names>Е. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrunina</surname><given-names>E. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Петрунина Екатерина Михайловна – заведующая патологоанатомическим отделением </p><p>620039, Екатеринбург, ул. 22-го Партсъезда, 5</p></bio><bio xml:lang="en"><p>Ekaterina M. Petrunina, Head of the Pathological Anatomy Department</p><p>ul. 22-go Parts’ezda 50, Ekaterinburg, 620039</p></bio><email xlink:type="simple">Ekaterina_b89@list.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0519-0523</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баженов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bazhenov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Баженов Александр Викторович – к. м. н., старший научный сотрудник лаборатории инвазивных технологий в составе научно-клинического отдела, врач-торакальный хирург туберкулезного легочно-хирургического отделения</p><p>620039, Екатеринбург, ул. 22-го Партсъезда, 5</p></bio><bio xml:lang="en"><p>Alexander V. Bazhenov, Candidate of Medicine, Senior Researcher, Laboratory of Invasive Technologies as part of the Scientific and Clinical Department, Thoracic Surgeon, Tuberculosis Pulmonary Surgery Department</p><p>ul. 22-go Parts’ezda 50, Ekaterinburg, 620039</p></bio><email xlink:type="simple">ai0803@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1106-4301</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ромахин</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Romakhin</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ромахин Алексей Сергеевич – врач торакальный хирург туберкулезного легочно-хирургического отделения </p><p>620039, Екатеринбург, ул. 22-го Партсъезда, 5</p></bio><bio xml:lang="en"><p>Alexey S. Romakhin, Thoracic Surgeon, Tuberculosis Pulmonary Surgery Department</p><p>ul. 22-go Parts’ezda 50, Ekaterinburg, 620039</p></bio><email xlink:type="simple">aleksei.romakhin@yandex.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Уральский научно-исследовательский институт фтизиопульмонологии – филиал Федерального государственного бюджетного учреждения «Национальный медицинский исследовательский центр фтизиопульмонологии и инфекционных заболеваний» Министерства здравоохранения Российской Федерации; &#13;
Федеральное государственное бюджетное образовательное учреждение высшего образования «Уральский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ural Federal Research Institute of Phthisiology and Pulmonology – a Branch of National Medical Research Center for Phthisiology, Pulmonology and Infectious Diseases, Healthcare Ministry of Russia; &#13;
Federal State Budget Educational Institution of Higher Education “Ural State Medical University” of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Уральский научно-исследовательский институт фтизиопульмонологии – филиал Федерального государственного бюджетного учреждения «Национальный медицинский исследовательский центр фтизиопульмонологии и инфекционных заболеваний» Министерства здравоохранения Российской Федерации; &#13;
Государственное бюджетное учреждение здравоохранения Свердловской области «Областной клинический медицинский центр фтизиопульмонологии и инфекционных заболеваний»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ural Federal Research Institute of Phthisiology and Pulmonology – a Branch of National Medical Research Center for Phthisiology, Pulmonology and Infectious Diseases, Healthcare Ministry of Russia; &#13;
State Budgetary Institution of Healthcare of Sverdlovsk Region “Regional clinical medical center of phthisiopulmonology and infectional diseases”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Государственное бюджетное учреждение здравоохранения Свердловской области «Областной клинический медицинский центр фтизиопульмонологии и инфекционных заболеваний»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Budgetary Institution of Healthcare of Sverdlovsk Region “Regional clinical medical center of phthisiopulmonology and infectional diseases”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Уральский научно-исследовательский институт фтизиопульмонологии – филиал Федерального государственного бюджетного учреждения «Национальный медицинский исследовательский центр фтизиопульмонологии и инфекционных заболеваний» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ural Federal Research Institute of Phthisiology and Pulmonology – a Branch of National Medical Research Center for Phthisiology, Pulmonology and Infectious Diseases, Healthcare Ministry of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>08</day><month>08</month><year>2025</year></pub-date><volume>35</volume><issue>4</issue><fpage>553</fpage><lpage>560</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бердников Р.Б., Андрющенко К.Ю., Заваров Н.С., Петрунина Е.М., Баженов А.В., Ромахин А.С., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Бердников Р.Б., Андрющенко К.Ю., Заваров Н.С., Петрунина Е.М., Баженов А.В., Ромахин А.С.</copyright-holder><copyright-holder xml:lang="en">Berdnikov R.B., Andryuschenko K.A., Zavarov N.S., Petrunina E.M., Bazhenov A.V., Romakhin A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.pulmonology.ru/pulm/article/view/4793">https://journal.pulmonology.ru/pulm/article/view/4793</self-uri><abstract><p>Киста Хаттори (КХ) – редкая патология, которая встречается исключительно среди лиц женского пола. В настоящее время в мире описано около 45–50 случаев. Все случаи описаны в иностранной литературе, в отечественной литературе сообщений о данной патологии не обнаружены. Этиология заболевания неизвестна, однако высказываются предложения о нарушении развития Мюллерова протока (эмбриональной структуры, являющейся зачатком половой системы у женщин). Рентгенологическая картина данной патологии очень неспецифична, в дифференциально-диагностический ряд входят опухоли легкого и плевры, кисты средостения – целомические и бронхогенные. Верифицируется данная патология при гистологическом исследовании операционного материала с привлечением дополнительных иммуногистохимических (ИГХ) методов.</p><p>Целью работы явилось информирование врачей-специалистов (пульмонологов, терапевтов, торакальных хирургов, онкологов, инфекционистов, акушеров-гинекологов) о существовании кисты заднего средостения, происходящей из зачатков Мюллерова протока, особенностях диагностики, клинического течения и вариантах лечения данной патологии.</p><p>Заключение. КХ в клинической деятельности врача-специалиста – явление очень редкое. Однако необходимо знать о существовании данной патологии и включать ее в дифференциально-диагностический ряд в случаях выявления округлых теней в средостении при рентгенологическом исследовании органов грудной клетки. Развитие болезни связано с нарушением внутриутробного развития Мюллерова протока. Для морфологического подтверждения диагноза необходимо, помимо световой микроскопии, выполнять ИГХ-исследование. Характерной чертой КХ является положительная окраска эпителиальных клеток, выстилающих кисту, на рецепторы к эстрогену и прогестерону. Хирургическая эксцизия рекомендуется для установления диагноза, облегчения симптомов заболевания и удаления эмбриональных тканей Мюллерова протока как источника потенциальной злокачественной трансформации. Прогноз заболевания благоприятный.</p></abstract><trans-abstract xml:lang="en"><p>The cyst of Hattori is a rare pathology occurring only in women. Only about 45 – 50 cases have been described in literature up until now. All cases were reported in foreign sources, there were no reports in Russian-speaking media. The etiology of disease is still unknown, however the disorder of Mullerian duct development (embryonal anlage of female reproductive system) was suggested as the cause. X-ray imaging of the cyst of Hattori is very nonspecific. The cyst should be differentiated with pleural tumors, lung tumors, bronchogenic and celomic mediastinal cysts. The diagnosis is verified by histology augmented with immunohistochemistry assays of the surgical sample.</p><p>The aim of the review was to inform the pulmonologists, general practitioners, infectious disease specialists, thoracic surgeons, oncologists and gynecologists about the cyst of posterior mediastinum that develops from the remnants of Mullerian duct, about its diagnosis, clinical course, and treatment. Also we present one clinical case of patient with Hattori’s cyst.</p><p>Conclusion. The cyst of Hattori is very rare in clinical practice. However, physicians should know about it and include it into differential diagnosis when rounded shadows are identified in mediastimun by chest X-ray. The development of the disease is related to the embryonal disorders of Mullerian duct formation. Not only the light microscopy, but also immunohistochemical assays are necessary for the morphological confirmation of the diagnosis. The specific feature of cyst of Hattori is positive staining for the estrogen and progesterone receptors of the cells lining the cyst. Surgical excision is recommended for diagnosis, to improve the symptoms, and to exclude potential origin of the malignant transformation in the embryonal tissues of Mullerian duct. A forecast for the cyst of Hattori is favorable.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>киста Хаттори</kwd><kwd>резекция образований средостения</kwd><kwd>киста Мюллерова протока</kwd><kwd>киста заднего средостения</kwd><kwd>рецепторы к эстрогену</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cyst of Hattori</kwd><kwd>resections of mediastinal tumors</kwd><kwd>Mullerian duct cyst</kwd><kwd>cyst of posterior mediastinum</kwd><kwd>estrogen receptors</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Hattori H. 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