pulmoПульмонологияPULMONOLOGIYA0869-01892541-9617Scientific and Practical Journal “PULMONOLOGIYA” LLC10.18093/0869-0189-2014-0-5-123-128pulmo-479Research ArticleКОНГРЕСС ERSCongress ERSОбзор материалов по саркоидозу, представленных на Конгрессе Европейского респираторного общества 2014 годаA review of data on sarcoidosis presented in the European Respiratory Society Congress 2014ВизельИ. Ю.Vizel'I. Yu.

к. м. н, профессор РАЕ, ассистент кафедры фтизиопульмонологии ГБОУ ВПО "Казанский ГМУ" Минздрава России; тел.: (843) 2798003

tatpulmo@mail.ruВизельА. А.Vizel'A. A.

д. м. н., профессор, зав. кафедрой фтизиопульмонологии ГБОУ ВПО "Казанский ГМУ" Минздрава России;тел.: (987) 2962599

lordara@inbox.ruГБОУ ВПО "Казанский государственный медицинский университет" Минздрава России: 420012, Республика Татарстан, Казань, ул. Бутлерова, 49РоссияState Institution Kazan State Medical University; Tatarstan, Kazan, RussiaRussian Federation20142810201405123128Copyright © Визель И.Ю., Визель А.А., 20142014Визель И.Ю., Визель А.А.Vizel' I.Y., Vizel' A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.pulmonology.ru/pulm/article/view/479

Представлен обзор тезисов докладов по саркоидозу, опубликованных в материалах Конгресса Европейского респираторного общества (Мюнхен, 2014). Большинство работ было посвящено оценке механизмов развития воспаления при саркоидозе, генетической предрасположенности. Серия работ была посвящена имидждиагностике с акцентом на выявление кардиосаркоидоза посредством магнитно-резонансной томографии. В работах, посвященных лечению, обсуждалось снижение гормональной нагрузки на больных. Россия была представлена публикациями специалистов из Москвы, СанктПетербурга, Новосибирска.

All abstracts on sarcoidosis presented in the European Respiratory Congress 2014 at Munich have been reviewed in this article. Most abstracts dealt with mechanisms of inflammation and genetic susceptibility in sarcoidosis. Several abstracts focused on image diagnosis particularly on MRI in cardiac sarcoidosis. Abstracts on treatment of sarcoidosis discussed reduction in steroid exposure on the patients. Russian scientists presented publications from Moscow, St.Petersburg, and Novosibirsk.

саркоидозКонгресс Европейского респираторного общества.sarcoidosisEuropean Respiratory Congress.ReferencesPuscinska E., Nowinski A., GoljanGeremek A. et al. Mortality in sarcoidosis, results from one centre, long termobservational study. Eur. Respir. J. 2014; 44 (Suppl. 58): 468.Puscinska E., Nowinski A., GoljanGeremek A. et al. Mortality in sarcoidosis, results from one centre, long termobservational study. Eur. Respir. J. 2014; 44 (Suppl. 58): 468.Sobiecka M., Bartosiewicz M., Lewandowska K. et al. Sarcoidosis related to interferon and ribavirin treatment of hepatitis C. Analysis of four cases. Eur. Respir. J. 2014; 44 (Suppl. 58): 467.Sobiecka M., Bartosiewicz M., Lewandowska K. et al. Sarcoidosis related to interferon and ribavirin treatment of hepatitis C. Analysis of four cases. Eur. Respir. J. 2014; 44 (Suppl. 58): 467.Catinon M., Chemarin C., Villard E. et al. Sarcoidosis and pulmonary dust: Mineralogical analysis (MA) and optical microscopy (OM). Eur. Respir. J. 2014; 44 (Suppl. 58): 472.Catinon M., Chemarin C., Villard E. et al. Sarcoidosis and pulmonary dust: Mineralogical analysis (MA) and optical microscopy (OM). Eur. Respir. J. 2014; 44 (Suppl. 58): 472.Papakosta D., Spyropoulos G., Domvri K. et al. Long termfollowup of Greek patients with pulmonary sarcoidosis. Relation to transforming growth factorbeta genetic profile. Eur. Respir. J. 2014; 44 (Suppl. 58): 784.Papakosta D., Spyropoulos G., Domvri K. et al. Long termfollowup of Greek patients with pulmonary sarcoidosis. Relation to transforming growth factorbeta genetic profile. Eur. Respir. J. 2014; 44 (Suppl. 58): 784.Peletidou S., Zifa E., Grammatikopoulos A., Malli F. et al. Mitochondrial tRNA gene mutations in patients with idiopathic pulmonary fibrosis (IPF) and sarcoidosis. Eur. Respir.J. 2014; 44 (Suppl. 58): 824.Peletidou S., Zifa E., Grammatikopoulos A., Malli F. et al. Mitochondrial tRNA gene mutations in patients with idiopathic pulmonary fibrosis (IPF) and sarcoidosis. Eur. Respir.J. 2014; 44 (Suppl. 58): 824.Calender A., Pacheco Y., Lebecque S. et al. Comparative phenotype and BTNL2 polymorphism in familial and sporadic sarcoidosis in the French SARCFAM cohort. Eur. Respir. J. 2014; 44 (Suppl. 58): 1734.Calender A., Pacheco Y., Lebecque S. et al. Comparative phenotype and BTNL2 polymorphism in familial and sporadic sarcoidosis in the French SARCFAM cohort. Eur. Respir. J. 2014; 44 (Suppl. 58): 1734.Milman N., Van Overeem Hansen T., Skov Jensen M. Does the BTNL2 genotype influence the course of disease in Danish sarcoidosis patients? Eur. Respir. J. 2014; 44 (Suppl. 58): 3224.Milman N., Van Overeem Hansen T., Skov Jensen M. Does the BTNL2 genotype influence the course of disease in Danish sarcoidosis patients? Eur. Respir. J. 2014; 44 (Suppl. 58): 3224.Navratilova Z., Novosadova E., Krsjakova T. et al. Differential bronchoalveolar expression of candidate microRNAs in chronic obstructive pulmonary disease, asth ma bronchiale and pulmonary. Eur. Respir. J. 2014; 44 (Suppl. 58): 198.Navratilova Z., Novosadova E., Krsjakova T. et al. Differential bronchoalveolar expression of candidate microRNAs in chronic obstructive pulmonary disease, asth ma bronchiale and pulmonary. Eur. Respir. J. 2014; 44 (Suppl. 58): 198.Kishore A., Navratilova Z., Kolek V., Petrek M. Detection of exosomal miRNA in pulmonary sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 199.Kishore A., Navratilova Z., Kolek V., Petrek M. Detection of exosomal miRNA in pulmonary sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 199.Harlander M., Zupancic M., Salobir B., Tercelj M. Biomarkers in sarcoidois followup: Angiotensinconverting enzyme or chitotriosidase? Eur. Respir. J. 2014; 44 (Suppl. 58): 462.Harlander M., Zupancic M., Salobir B., Tercelj M. Biomarkers in sarcoidois followup: Angiotensinconverting enzyme or chitotriosidase? Eur. Respir. J. 2014; 44 (Suppl. 58): 462.VucinicMihailovic V., Sumarac Z., Jovanovic D. et al. Assessing sarcoidosis activity: Is serum chitotriosidase a reliable marker? Study of 430 patients and 264 healthy controls. Eur. Respir. J. 2014; 44 (Suppl. 58): 1735.VucinicMihailovic V., Sumarac Z., Jovanovic D. et al. Assessing sarcoidosis activity: Is serum chitotriosidase a reliable marker? Study of 430 patients and 264 healthy controls. Eur. Respir. J. 2014; 44 (Suppl. 58): 1735.Doubkova M., Karpisek M., Mazoch J. et al. Prognostic significance of selected biomarkers in idiopathic pulmonary fibrosis, sarcoidosis, and chronic pulmonary obstructive disease. Eur. Respir. J. 2014; 44 (Suppl. 58): 471.Doubkova M., Karpisek M., Mazoch J. et al. Prognostic significance of selected biomarkers in idiopathic pulmonary fibrosis, sarcoidosis, and chronic pulmonary obstructive disease. Eur. Respir. J. 2014; 44 (Suppl. 58): 471.Bargagli E., Landi C., Carleo A. et al. Proteomic investigation of pulmonary sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 3878.Bargagli E., Landi C., Carleo A. et al. Proteomic investigation of pulmonary sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 3878.Lyamina S., Demyanenko N., Shelukhina S. et al. Functional phenotype of immune response and alveolarmacrophages phenotype in pulmonary sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 1476.Lyamina S., Demyanenko N., Shelukhina S. et al. Functional phenotype of immune response and alveolarmacrophages phenotype in pulmonary sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 1476.Osinska I., Wolosz D., Urbankowski T., DomagalaKulawik J. LSC 2014 abstract – M1/M2 subpopulations of macrophages in patients with sarcoidosis influence of smoking status. Eur. Respir. J. 2014; 44 (Suppl. 58): 1733.Osinska I., Wolosz D., Urbankowski T., DomagalaKulawik J. LSC 2014 abstract – M1/M2 subpopulations of macrophages in patients with sarcoidosis influence of smoking status. Eur. Respir. J. 2014; 44 (Suppl. 58): 1733.Dubaniewicz A. Heat shock proteins as 'danger signals' in sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 3790.Dubaniewicz A. Heat shock proteins as 'danger signals' in sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 3790.Roussou A., Papaioannou A., Manali E.et al. Serum levels of sestrin 2 in patients with sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 3797.Roussou A., Papaioannou A., Manali E.et al. Serum levels of sestrin 2 in patients with sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 3797.Chandrashekariah S., Rosha D. Sarcoidosis in India: Investigation into vitamin D and calcium metabolism. Eur. Respir. J. 2014; 44 (Suppl. 58): 3777.Chandrashekariah S., Rosha D. Sarcoidosis in India: Investigation into vitamin D and calcium metabolism. Eur. Respir. J. 2014; 44 (Suppl. 58): 3777.Kouranos V., Tzelepis G., Rapti A. et al. Diagnosis of cardiac sarcoidosis: A crossectional study in 327 consecutive patients. Eur. Respir. J. 2014; 44 (Suppl. 58): 463.Kouranos V., Tzelepis G., Rapti A. et al. Diagnosis of cardiac sarcoidosis: A crossectional study in 327 consecutive patients. Eur. Respir. J. 2014; 44 (Suppl. 58): 463.Tosun M., Keskin S., Akilli H. et al. Determination of cardiac involvement of sarcoidosis with cardiac MR, ECHO and Holter ECG. Eur. Respir. J. 2014; 44 (Suppl. 58): 470.Tosun M., Keskin S., Akilli H. et al. Determination of cardiac involvement of sarcoidosis with cardiac MR, ECHO and Holter ECG. Eur. Respir. J. 2014; 44 (Suppl. 58): 470.Stanton K., Ganigara M., Corte T. et al. The utility of cardiac magnetic resonance imaging in the diagnosis of cardiac sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 1728.Stanton K., Ganigara M., Corte T. et al. The utility of cardiac magnetic resonance imaging in the diagnosis of cardiac sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 1728.Kouranos V., Rapti A., Peros E. et al. Predictors of cardio vascular events in newly diagnosed patients with sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 474.Kouranos V., Rapti A., Peros E. et al. Predictors of cardio vascular events in newly diagnosed patients with sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 474.Papiris S., Georgakopoulos A., Pianou N. et al 18FFDG PET/CT for the evaluation of sarcoidosis patients. Eur. Respir. J. 2014; 44 (Suppl. 58): 657.Papiris S., Georgakopoulos A., Pianou N. et al 18FFDG PET/CT for the evaluation of sarcoidosis patients. Eur. Respir. J. 2014; 44 (Suppl. 58): 657.Dal Farra S., Picchio M., Incerti E. et al. Fluorine18fluo rodeoxyglucose positron emission tomography (18FFDG PET) may be useful in the management of sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 3222.Dal Farra S., Picchio M., Incerti E. et al. Fluorine18fluo rodeoxyglucose positron emission tomography (18FFDG PET) may be useful in the management of sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 3222.Menon B., Dogra V., Nima G. et al. Evaluation of thoracic HRCT findings in sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 664.Menon B., Dogra V., Nima G. et al. Evaluation of thoracic HRCT findings in sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 664.Hirche T.O., Hirche H., Cui X.W. et al. Ultrasound evaluation of mediastinal lymphadenopathy in patients with sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 671.Hirche T.O., Hirche H., Cui X.W. et al. Ultrasound evaluation of mediastinal lymphadenopathy in patients with sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 671.Marshall A., Ahmed L., Chalmers G. Experience of endobronchial ultrasound – transbronchial needle aspiration (EBUSTBNA) in granulomatous disease. Eur. Respir. J. 2014; 44 (Suppl. 58): 469.Marshall A., Ahmed L., Chalmers G. Experience of endobronchial ultrasound – transbronchial needle aspiration (EBUSTBNA) in granulomatous disease. Eur. Respir. J. 2014; 44 (Suppl. 58): 469.Kameneva M., Syrtsova D., Baranova O.et al. A. Changes in lung mechanics and gas exchange in patients with pulmonary sarcoidosis (PS). Eur. Respir. J. 2014; 44 (Suppl. 58): 4271.Kameneva M., Syrtsova D., Baranova O.et al. A. Changes in lung mechanics and gas exchange in patients with pulmonary sarcoidosis (PS). Eur. Respir. J. 2014; 44 (Suppl. 58): 4271.Karagiannis K., Bikov A., Bonifazi M. et al. Impulse oscillometry measurements are correlated to quality of life in patients with pulmonary sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 740.Karagiannis K., Bikov A., Bonifazi M. et al. Impulse oscillometry measurements are correlated to quality of life in patients with pulmonary sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 740.Boros P., MartusewiczBoros M., Wesolowski S. Impact of smoking habit on lung function in a large cohort sarcoidosis patients. Eur. Respir. J. 2014; 44 (Suppl. 58): 475.Boros P., MartusewiczBoros M., Wesolowski S. Impact of smoking habit on lung function in a large cohort sarcoidosis patients. Eur. Respir. J. 2014; 44 (Suppl. 58): 475.Karadalli M.N., Bosnak Guclu M., Camcioglu B. et al. Clinical determinants and chronotrophic responses of maximal exercise capacity in patients with early stage of sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 2158.Karadalli M.N., Bosnak Guclu M., Camcioglu B. et al. Clinical determinants and chronotrophic responses of maximal exercise capacity in patients with early stage of sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 2158.Laushkina Z. The analysis of factors associated with misdiagnosis sarcoidosis in TB hospital. Eur. Respir. J. 2014; 44 (Suppl. 58): 2676.Laushkina Z. The analysis of factors associated with misdiagnosis sarcoidosis in TB hospital. Eur. Respir. J. 2014; 44 (Suppl. 58): 2676.Nowinski A., Puscinska E., GoljanGeremek A. et al. Comorbidities associated with sarcoidosis – Results from longterm observational study. Eur. Respir. J. 2014; 44 (Suppl. 58): 461.Nowinski A., Puscinska E., GoljanGeremek A. et al. Comorbidities associated with sarcoidosis – Results from longterm observational study. Eur. Respir. J. 2014; 44 (Suppl. 58): 461.Nathan N., Marcelo P., Houdouin V. et al. Is pulmonary sarcoidosis more severe in children? A multicentric retrospective study. Eur. Respir. J. 2014; 44 (Suppl. 58): 465.Nathan N., Marcelo P., Houdouin V. et al. Is pulmonary sarcoidosis more severe in children? A multicentric retrospective study. Eur. Respir. J. 2014; 44 (Suppl. 58): 465.Güungör S., Yalçinsoy M., Usta Bülbül E. et al. Extrapulmonary involvement in sarcoidosis patients. Eur. Respir. J. 2014; 44 (Suppl. 58): 3751.Güungör S., Yalçinsoy M., Usta Bülbül E. et al. Extrapulmonary involvement in sarcoidosis patients. Eur. Respir. J. 2014; 44 (Suppl. 58): 3751.Romanov V. Atypical variants of clinical course of sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 3782.Romanov V. Atypical variants of clinical course of sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 3782.Baranova O., Perlei V., Gichkin A. et al. Pulmonary embolism (PE) in patients with pulmonary sarcoidosis (PS). Eur. Respir. J. 2014; 44 (Suppl. 58): 4508.Baranova O., Perlei V., Gichkin A. et al. Pulmonary embolism (PE) in patients with pulmonary sarcoidosis (PS). Eur. Respir. J. 2014; 44 (Suppl. 58): 4508.Omcikus M., Vucinic V., Filipovic S., Videnovic J. Cognitive failure in sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 460.Omcikus M., Vucinic V., Filipovic S., Videnovic J. Cognitive failure in sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 460.MartusewiczBoros M., Boros P., Wiatr E., Roszkowski Sliz K. How many patients require corticosteroid treatment in sarcoidosis? – Preliminary study. Eur. Respir. J. 2014; 44 (Suppl. 58): 464.MartusewiczBoros M., Boros P., Wiatr E., Roszkowski Sliz K. How many patients require corticosteroid treatment in sarcoidosis? – Preliminary study. Eur. Respir. J. 2014; 44 (Suppl. 58): 464.Grah C., Thieme C., Seiberth R. et al. Benefit of steroid free treatment compared to standard therapy (ST) in pulmonary sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 3765.Grah C., Thieme C., Seiberth R. et al. Benefit of steroid free treatment compared to standard therapy (ST) in pulmonary sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 3765.Goljan Geremek A., Bednarek M., Puscinska E. et al. Methotrexate (MTX) as a single agent for treating chronic, progressive sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 473.Goljan Geremek A., Bednarek M., Puscinska E. et al. Methotrexate (MTX) as a single agent for treating chronic, progressive sarcoidosis. Eur. Respir. J. 2014; 44 (Suppl. 58): 473.Baranova O., Voinov V., Baklanova O. 30 years experience of plasmapheresis using in complex treatment of pulmonary sarcoidosis (PS). Eur. Respir. J. 2014; 44 (Suppl. 58): 4510.Baranova O., Voinov V., Baklanova O. 30 years experience of plasmapheresis using in complex treatment of pulmonary sarcoidosis (PS). Eur. Respir. J. 2014; 44 (Suppl. 58): 4510.Hostettler K., Baty F., Kleiner R. et al. Bosentan does not improve outcome in patients with steroidresistant pulmonary sarcoidosis – Results from a doubleblind placebo controlled phase 2 trial. Eur. Respir. J. 2014; 44 (Suppl. 58): 466.Hostettler K., Baty F., Kleiner R. et al. Bosentan does not improve outcome in patients with steroidresistant pulmonary sarcoidosis – Results from a doubleblind placebo controlled phase 2 trial. Eur. Respir. J. 2014; 44 (Suppl. 58): 466.

The authors declare that there are no conflicts of interest present.