pulmoПульмонологияPULMONOLOGIYA0869-01892541-9617Scientific and Practical Journal “PULMONOLOGIYA” LLC10.18093/0869-0189-2025-35-1-16-41pulmo-4712Research ArticleКЛИНИЧЕСКИЕ РЕКОМЕНДАЦИИCLINICAL GUIDELINESГиперчувствительный пневмонит: федеральные клинические рекомендации по диагностике и лечениюFederal clinical guidelines on diagnosis and treatment of hypersensitivity pneumonitishttps://orcid.org/0000-0002-5999-2150АвдеевС. Н.AvdeevS. N.

Авдеев Сергей Николаевич – д. м. н., профессор, академик Российской академии наук; директор Национального медицинского исследовательского центра по профилю «Пульмонология»; заведующий кафедрой пульмонологии Института клинической медицины имени Н.В.Склифосовского Федерального государственного автономного образовательного учреждения высшего образования «Первый Московский государственный медицинский университет имени И.М.Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский Университет); руководитель клинического отдела Федерального государственного бюджетного учреждения «Научно-исследовательский институт пульмонологии» Федерального медико-биологического агентства; главный внештатный пульмонолог Министерства здравоохранения Российской Федерации

119991, Россия, Москва, ул. Трубецкая, 8, стр. 2

115682, Россия, Москва, Ореховый бульвар, 28, тел.: (495) 708-35-76

SPIN-код: 1645-5524

Sergey N. Avdeev, Doctor of Medicine, Professor, Academician of Russian Academy of Sciences, Director of the National Medical Research Center for Pulmonology; Head of the Department of Pulmonology, N.V.Sklifosovsky Institute of Clinical Medicine, Federal State Autonomous Educational Institution of Higher Education I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University); Head of Clinical Department, Federal State Budgetary Institution “Pulmonology Scientific Research Institute” under Federal Medical and Biological Agency of Russian Federation; Chief Pulmonologist of the Ministry of Health of the Russian Federation

ul. Trubetskaya 8, build. 2, Moscow, 119991

Orekhovyy bul’var 28, Moscow, 115682, tel.: (495) 708-35-76

SPIN-code: 1645-5524

serg_avdeev@list.ruhttps://orcid.org/0000-0002-4044-674XАйсановЗ. Р.AisanovZ. R.

Айсанов Заурбек Рамазанович – д. м. н., профессор кафедры пульмонологии 

117997, Москва, ул. Островитянова, 1, тел.: (495) 965-34-66 

Zaurbek R. Aisanov, Doctor of Medicine, Professor, Department of Pulmonology

ul. Ostrovityanova 1, Moscow, 117997, tel.: (495) 965-34-66

aisanov@mail.ruhttps://orcid.org/0000-0001-5028-5276ВизельА. А.VizelA. A.

Визель Александр Андреевич – д. м. н., профессор, заведующий кафедрой фтизиопульмонологии

Author ID: 195447 

420012, Республика Татарстан, Казань, ул. Бутлерова, 49, тел.: (843) 236-09-22 

Aleksandr A. Vizel, Doctor of Medicine, Professor, Head of Department of Phthisiology and Pulmonology

Author ID: 195447 

ul. Butlerova 49, Republic of Tatarstan, Kazan, 420012, tel.: (843) 236-09-22 

lordara@inbox.ruhttps://orcid.org/0000-0001-8982-5292ДемкоИ. В.DemkoI. V.

Демко Ирина Владимировна – д. м. н., профессор, заведующая кафедрой внутренних болезней № 2 с курсом постдипломного образования; заведующая легочно-аллергологическим центром

660022, Красноярск, ул. Партизана Железняка, 1

660022, Красноярск, ул. Партизана Железняка, 3А

тел.: (391) 220-13-57 

Irina V. Demko, Doctor of Medicine, Professor, Head of Department of Internal Medicine No.2 with Postgraduate Physician Training Course; Head of Pulmonary Allergology Сenter

ul. Partizana Zheleznyaka 1, Krasnoyarsk, 660022 

ul. Partizana Zheleznyaka 3А, Krasnoyarsk, 660022, tel.: (391) 220-13-57 

demko64@mail.ruhttps://orcid.org/0000-0001-5191-445XИльковичМ. М.IlkovichM. M.

Илькович Михаил Михайлович – д. м. н., профессор, заведующий кафедрой пульмонологии факультета последипломного образования, директор Научно-исследовательского института интерстициальных и орфанных заболеваний легких

197022, Санкт-Петербург, ул. Льва Толстого, 6–8, тел.: (812) 338-78-32 

Mikhail M. Ilkovich, Doctor of Medicine, Professor, Head of the Pulmonology Department, Faculty of Postgraduate Education, Director, Research Institute of Interstitial and Orphan Lung Diseases

ul. L`va Tolstogo 6 – 8, Saint-Petersburg, 197022, tel.: (812) 338-78-32

mih.ilkovich@yandex.ruhttps://orcid.org/0000-0002-5498-9008КиняйкинМ. Ф.KiniaikinM. F.

Киняйкин Михаил Федорович – к. м. н., доцент Института терапии и инструментальной диагностики; заведующий Краевым пульмонологическим центром

690002, Владивосток, Проспект Острякова, 2

690091, Владивосток, ул. Алеутская, 57, тел.: (423) 240-08-46 

Mihail F. Kiniaikin, Candidate of Medicine, Associate Professor, Institute of Therapy and Instrumental Diagnostics

Prospekt Ostryakova 2, Vladivostok, 690002 

ul. Aleutskaya 57, Vladivostok, 690091, tel.: (423) 240-08-46

589014@bk.ruhttps://orcid.org/0000-0002-1620-7159ЛещенкоИ. В.LeshсhenkoI. V.

Лещенко Игорь Викторович – д. м. н., профессор; профессор кафедры инфекционных болезней, фтизиатрии и пульмонологии; главный научный сотрудник; научный руководитель клиники; главный внештатный специалист-пульмонолог Министерства здравоохранения Свердловской области, заслуженный врач Российской Федерации

620109, Екатеринбург, ул. Заводская, 29

620028, Екатеринбург, ул. Репина, 3

620039, Екатеринбург, ул. 22-го Партсъезда, 5, тел.: (912) 288-28-23 

Igor V. Leshсhenko, Doctor of Medicine, Professor; Professor, Department of Infectious Diseases, Phthisiology and Pulmonology; Chief Researcher; Scientific Director

ul. Repina 3, Ekaterinburg, 620028 

ul. 22-go Parts’ezda 50, Ekaterinburg, 620039 

ul. Zavodskaya 29, Ekaterinburg, 620109, tel.: (912) 288-28-23

leshchenkoiv@yandex.ruhttps://orcid.org/0000-0002-3374-9320ОрловаГ. П.OrlovaG. P.

Орлова Галина Павловна – д. м. н., ведущий научный сотрудник Научно-исследовательского института интерстициальных и орфанных заболеваний легких

197022, Санкт-Петербург, ул. Льва Толстого, 6–8, тел.: (812) 499-68-02 

Galina P. Orlova, Doctor of Medicine, Leading Researcher, Research Institute of Interstitial and Orphan Lung Diseases

ul. L`va Tolstogo 6 – 8, Saint-Petersburg, 197022, tel.: 812) 499-68-02 

galorlova@mail.ruhttps://orcid.org/0000-0001-8170-1260СамсоноваМ. В.SamsonovaM. V.

Самсонова Мария Викторовна – д. м. н., заведующая лабораторией патологической анатомии и иммунологии

115682, Москва, Ореховый бульвар, 28, тел.: (495) 465-58-59 

Maria V. Samsonova, Doctor of Medicine, Head of Laboratory of Pathological Anatomy and Immunology

Orekhovyy bul’var 28, Moscow, 115682, tel.: (495) 465-58-59 

samary@mail.ruhttps://orcid.org/0000-0003-4678-3904ТитоваО. Н.TitovaO. N.

Титова Ольга Николаевна – д. м. н., профессор, директор Научно-исследовательского института пульмонологии

197022, Санкт-Петербург, ул. Льва Толстого, 6–8, тел.: (812) 338-78-40 

Ol’ga N. Titova, Doctor of Medicine, Professor, Director, Research Institute of Pulmonology, Scientific and Clinical Research Center

ul. L`va Tolstogo 6 – 8, Saint-Petersburg, 197022, tel.: (812) 338-78-40 

titova-on@mail.ruhttps://orcid.org/0000-0002-0685-4133ТрушенкоН. В.TrushenkoN. V.

Трушенко Наталья Владимировна – к. м. н., доцент кафедры пульмонологии Института клинической медицины имени Н.В.Склифосовского; научный сотрудник научно-методического центра мониторинга и контроля болезней органов дыхания

119991, Москва, ул. Трубецкая, 8, стр. 2

115682, Москва, Ореховый бульвар, 28, тел.: (495) 708-35-76 

Natal’ya V. Trushenko, Candidate of Medicine, Associate Professor, Department of Pulmonology, N.V.Sklifosovsky Institute of Clinical Medicine; Researcher, Scientific and Methodological Center for Monitoring and Control of Respiratory Diseases

ul. Trubetskaya 8, build. 2, Moscow, 119991 

Orekhovyy bul’var 28, Moscow, 115682, tel.: (495) 708-35-76 

trushenko.natalia@yandex.ruhttps://orcid.org/0000-0003-2742-3794ТрофименкоИ. Н.TrofimenkoI. N.

Трофименко Ирина Николаевна – д. м. н., доцент, заведующая кафедрой клинической аллергологии и пульмонологии

664049, Иркутск, мкр Юбилейный, 100, тел.: (9148) 77-80-96 

Irina N. Trofimenko, Doctor of Medicine, Assistant Professor, Head of Department of Clinical Allergology and Pulmonology

mkr-n Yubileynyy 100, Irkutsk, 664079, tel.: (9148) 77-80-96

tin11@mail.ruhttps://orcid.org/0000-0003-3931-1431ТюринИ. Е.TyurinI. E.

Тюрин Игорь Евгеньевич – д. м. н., профессор, заведующий кафедрой рентгенологии и радиологии

125993, Москва, ул. Баррикадная, 2 / 1, стр. 1, тел.: (903) 758-46-52 

Igor’ E. Tyurin, Doctor of Medicine, Professor, Head of Department of Radiology

ul. Barrikadnaya 2/1, Moscow, 123995, tel.: (903) 758-46-52

igortyurin@gmail.comhttps://orcid.org/0000-0003-4307-9321ФедотовВ. Д.FedotovV. D.

Федотов Василий Дмитриевич – к. м. н., доцент кафедры госпитальной терапии имени В.Г.Вогралика; старший научный сотрудник клинического отдела; главный внештатный пульмонолог Министерства здравоохранения Нижегородской области

603005, Нижний Новгород, пл. Минина и Пожарского, 10 / 1

603105, Нижний Новгород, ул. Семашко, 20, тел.: (831) 419-61-94 

Vasily D. Fedotov, Candidate of Medicine, Associate Professor, Department of Hospital Therapy named after V.G.Vogralik; Senior Researcher, Clinical Department; Chief Freelance Pulmonologist of the Ministry of Health of the Nizhny Novgorod Region

pl. Minina i Pozharskogo 10/1, Nizhniy Novgorod, 603950

ul. Semashko 20, Nizhniy Novgorod, 603105, tel.: (831) 419-61-94 

basil11@yandex.ruhttps://orcid.org/0000-0002-0158-7056ЧерняевА. Л.ChernyaevA. L.

Черняев Андрей Львович – д. м. н., профессор, заведующий отделом фундаментальной пульмонологии; профессор кафедры патологической анатомии и клинической патологической анатомии лечебного факультета; ведущий научный сотрудник лаборатории клинической морфологии

115682, Москва, Ореховый бульвар, 28

117997, Москва, ул. Островитянова, 1

117418, Москва, ул. Цюрупы, 3, тел.: (495) 465-58-59 

Andrey L. Chernyaev, Doctor of Medicine, Professor, Head of the Department of Fundamental Pulmonology; Professor, Department of Pathological Anatomy and Clinical Pathological Anatomy, Faculty of Medicine; Leading Researcher, Laboratory of Clinical Morphology, Avtsyn Research Institute оf Human Morphology

Orekhovyy bul’var 28, Moscow, 115682 

ul. Ostrovityanova 1, Moscow, 117997 

Tsyurupy 3, Moscow, 117418, tel.:(495) 465-58-59

cheral12@gmail.comhttps://orcid.org/0000-0002-5902-6198ЧернякБ. А.ChernyakB. A.

Черняк Борис Анатольевич – д. м. н., профессор кафедры клинической аллергологии и пульмонологии

664049, Иркутск, мкр Юбилейный, 100, тел.: (3952) 46-53-26 

Boris A. Chernyak, Doctor of Medicine, Professor, Department of Clinical Allergology and Pulmonology

mkr-n Yubileynyy 100, Irkutsk, 664079, tel.: (3952) 46-53-26 

ba.chernyak@gmail.comhttps://orcid.org/0000-0002-5536-9388ЧикинаС. Ю.ChikinaS. Yu.

Чикина Светлана Юрьевна – к. м. н., доцент кафедры пульмонологии Института клинической медицины имени Н.В.Склифосовского

119991, Москва, ул. Трубецкая, 8, стр. 2, тел.: (916) 116-04-03 

Svetlana Yu. Chikina, Candidate of Medicine, Associate Professor, Department of Pulmonology, N.V.Sklifosovskiy Institute of Clinical Medicine

ul. Trubetskaya 8, build. 2, Moscow, 119991, tel.: (916) 116-04-03 

svch@list.ruhttps://orcid.org/0000-0002-1908-5601ШмелевЕ. И.ShmelevE. I.

Шмелев Евгений Иванович – д. м. н., профессор, заведующий отделом дифференциальной диагностики туберкулеза легких и экстракорпоральных методов лечения

107564, Москва, Яузская аллея, 2, тел.: (499) 785-90-08 

Evgeny I. Shmelev, Doctor of Medicine, Professor, Head of Differential Diagnosis of Pulmonary Tuberculosis and Extracorporeal Methods of Treatment Department

Yauzskaya alleya 2, Moscow, 107564,  tel.: (499) 785-90-08

eishmelev@mail.ruФедеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М.Сеченова Министерства здравоохранения Российской Федерации (Сеченовский Университет); Федеральное государственное бюджетное учреждение «Научно-исследовательский институт пульмонологии» Федерального медико-биологического агентства России»РоссияFederal State Autonomous Educational Institution of Higher Education I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University); Federal State Budgetary Institution “Pulmonology Scientific Research Institute” under Federal Medical and Biological Agency of Russian FederationRussian FederationФедеральное государственное автономное образовательное учреждение высшего образования «Российский национальный исследовательский медицинский университет имени Н.И.Пирогова» Министерства здравоохранения Российской ФедерацииРоссияFederal State Autonomous Educational Institution of Higher Education “N.I.Pirogov Russian National Research Medical University” of the Ministry of Health of the Russian FederationRussian FederationФедеральное государственное бюджетное образовательное учреждение высшего образования «Казанский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииРоссияFederal State Budgetary Educational Institution of Higher Education Kazan State Medical University of the Ministry of Health of the Russian FederationRussian FederationФедеральное государственное бюджетное образовательное учреждение высшего образования «Красноярский государственный медицинский университет имени профессора В.Ф.Войно-Ясенецкого» Министерства здравоохранения Российской Федерации ; Краевое государственное бюджетное учреждение здравоохранения «Краевая клиническая больница»РоссияFederal State Budgetary Educational Institution of Higher Education “Krasnoyarsk State Medical University named after Professor V.F.Voyno-Yasenetsky” of the Ministry of Health of the Russian Federation ; Regional State Budgetary Healthcare Institution “Regional Clinical Hospital”Russian FederationФедеральное государственное бюджетное образовательное учреждение высшего образования «Первый Санкт-Петербургский государственный медицинский университет имени академика И.П.Павлова» Министерства здравоохранения Российской ФедерацииРоссияFederal State Budgetary Educational Institution of Higher Education “Pavlov First Saint Petersburg State Medical University”, Ministry of Healthcare of Russian FederationRussian FederationФедеральное государственное бюджетное образовательное учреждение высшего образования «Тихоокеанский государственный медицинский университет» Министерства здравоохранения Российской Федерации ; Государственное бюджетное учреждение здравоохранения «Приморская краевая клиническая больница № 1»РоссияFederal State Budgetary Educational Institution of Higher Education Tver State Medical University of the Ministry of Health of the Russian Federation ; State Budgetary Healthcare Institution “Primorsky Regional Clinical Hospital No.1”Russian FederationФедеральное государственное бюджетное образовательное учреждение высшего образования «Уральский государственный медицинский университет» Министерства здравоохранения Российской Федерации ; Уральский научно-исследовательский институт фтизиопульмонологии – филиал Федерального государственного бюджетного учреждения «Национальный медицинский исследовательский центр фтизиопульмонологии и инфекционных заболеваний» Министерства здравоохранения Российской Федерации ; Общество с ограниченной ответственностью «Медицинское объединение “Новая больница”»РоссияFederal State Budget Educational Institution of Higher Education “Ural State Medical University” of the Ministry of Health of the Russian Federation ; Ural Federal Research Institute of Phthisiology and Pulmonology – a Branch of National Medical Research Center for Phthisiology, Pulmonology and Infectious Diseases, Healthcare Ministry of Russia ; Limited Liability Company “Novaya bol’nitsa” Clinical AssociationRussian FederationФедеральное государственное бюджетное учреждение «Научно-исследовательский институт пульмонологии» Федерального медико-биологического агентства России»РоссияFederal State Budgetary Institution “Pulmonology Scientific Research Institute” under Federal Medical and Biological Agency of Russian FederationRussian FederationФедеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М.Сеченова Министерства здравоохранения Российской Федерации (Сеченовский Университет) ; Федеральное государственное бюджетное учреждение «Научно-исследовательский институт пульмонологии» Федерального медико-биологического агентства России»РоссияFederal State Autonomous Educational Institution of Higher Education I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University) ; Federal State Budgetary Institution “Pulmonology Scientific Research Institute” under Federal Medical and Biological Agency of Russian FederationRussian FederationИркутская государственная медицинская академия последипломного образования – филиал Федерального государственного бюджетного образовательного учреждения дополнительного профессионального образования «Российская медицинская академия непрерывного профессионального образования» Министерства здравоохранения Российской ФедерацииРоссияIrkutsk State Medical Academy of Postgraduate Education – a Branch Campus of the Federal State Budgetary Educational Institution of Further Professional Education “Russian Medical Academy of Continuing Professional Education”, Healthcare Ministry of the Russian FederationRussian FederationФедеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования «Российская медицинская академия непрерывного профессионального образования» Министерства здравоохранения Российской ФедерацииРоссияFederal State Budgetary Educational Institution of Additional Professional Education “Russian Medical Academy of Continuous Professional Education”, Ministry of Health of RussiaRussian FederationФедеральное государственное бюджетное образовательное учреждение высшего образования «Приволжский исследовательский медицинский университет» Министерства здравоохранения Российской Федерации ; Федеральное бюджетное учреждение науки «Нижегородский научно-исследовательский институт гигиены и профпатологии» Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человекаРоссияFederal State Budgetary Educational Institution of Higher Education “Privolzhsky Research Medical University”, Ministry of Healthcare of the Russian Federation ; Federal Budgetary Institution of Science “Nizhny Novgorod Scientific Research Institute of Hygiene and Occupational Pathology”, Federal Service for Surveillance on Consumer Rights Protection and Human WellbeingRussian FederationФедеральное государственное бюджетное учреждение «Научно-исследовательский институт пульмонологии» Федерального медико-биологического агентства России» ; Федеральное государственное автономное образовательное учреждение высшего образования «Российский национальный исследовательский медицинский университет имени Н.И.Пирогова» Министерства здравоохранения Российской Федерации ; Научно-исследовательский институт морфологии человека имени академика А.П.Авцына Федерального государственного бюджетного научного учреждения «Российский научный центр хирургии имени академика Б.В.Петровского»РоссияFederal State Budgetary Institution “Pulmonology Scientific Research Institute” under Federal Medical and Biological Agency of Russian Federation ; Federal State Autonomous Educational Institution of Higher Education “N.I.Pirogov Russian National Research Medical University” of the Ministry of Health of the Russian Federation ; Avtsyn Research Institute of Human Morphology of Federal State Budgetary Scientific Institution “Petrovsky National Research Centre of Surgery”Russian FederationФедеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М.Сеченова Министерства здравоохранения Российской Федерации (Сеченовский Университет)РоссияFederal State Autonomous Educational Institution of Higher Education I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)Russian FederationФедеральное государственное бюджетное научное учреждение «Центральный научно-исследовательский институт туберкулеза» Министерства науки и высшего образования Российской ФедерацииРоссияFederal State Budgetary Scientific Institution “Central Research Institute of Tuberculosis”, Ministry of Science and Higher Education of the Russian FederationRussian Federation2025120220253511641Copyright © Авдеев С.Н., Айсанов З.Р., Визель А.А., Демко И.В., Илькович М.М., Киняйкин М.Ф., Лещенко И.В., Орлова Г.П., Самсонова М.В., Титова О.Н., Трушенко Н.В., Трофименко И.Н., Тюрин И.Е., Федотов В.Д., Черняев А.Л., Черняк Б.А., Чикина С.Ю., Шмелев Е.И., 20252025Авдеев С.Н., Айсанов З.Р., Визель А.А., Демко И.В., Илькович М.М., Киняйкин М.Ф., Лещенко И.В., Орлова Г.П., Самсонова М.В., Титова О.Н., Трушенко Н.В., Трофименко И.Н., Тюрин И.Е., Федотов В.Д., Черняев А.Л., Черняк Б.А., Чикина С.Ю., Шмелев Е.И.Avdeev S.N., Aisanov Z.R., Vizel A.A., Demko I.V., Ilkovich M.M., Kiniaikin M.F., Leshсhenko I.V., Orlova G.P., Samsonova M.V., Titova O.N., Trushenko N.V., Trofimenko I.N., Tyurin I.E., Fedotov V.D., Chernyaev A.L., Chernyak B.A., Chikina S.Y., Shmelev E.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.pulmonology.ru/pulm/article/view/4712

Гиперчувствительный пневмонит (ГП) представляет собой воспалительное и / или фиброзирующее заболевание легких, которое возникает в ответ на повторные ингаляции аэрозольных антигенов широкого спектра. Распространенность ГП составляет от 0,3 до 0,9 случая на 100 000 населения. Основу терапии ГП составляют глюкокортикостероиды, иммуносупрессоры, препараты с антифибротическими свойствами. Целевой аудиторией данных клинических рекомендаций являются врачи общей практики, терапевты, пульмонологи, патологоанатомы, рентгенологи и врачи по медицинской реабилитации. Методы. Каждый тезис-рекомендация по проведению диагностических и лечебных мероприятий оценивается по шкалам уровней достоверности доказательств от 1 до 5 и шкале оценки уровней убедительности рекомендаций по категориям А, В, С. Клинические рекомендации содержат также комментарии и разъяснения к указанным тезисам-рекомендациям, алгоритмы по диагностике и лечению идиопатического легочного фиброза, справочные материалы. Заключение. По данным представленных клинических рекомендаций освещаются современные сведения об этиологии и патогенезе, клинических проявлениях, диагностике и лечении ГП. Клинические рекомендации одобрены Научно-практическим советом Министерства здравоохранения Российской Федерации в 2023 г.

Hypersensitivity pneumonitis (HP) is an inflammatory and/or fibrotic lung disease that occurs in response to repeated inhalation of broad-spectrum aerosol antigens. The prevalence of HP ranges from 0.3 to 0.9 cases per 100,000 population. The basis treatment of HP therapy includes glucocorticoids, immunosuppressants, and antifibrotic drugs. The target audience of these clinical recommendations are general practitioners, pulmonologists, pathologists, radiologists, and medical rehabilitation specialists. Methods. Each thesis-recommendation for diagnostic and therapeutic measures is evaluated on a scale of evidence reliability from 1 to 5 and a scale of the recommendation persuasiveness with the categories A, B, C. The guidelines also contain comments and explanations to these thesis-recommendations, algorithms for the diagnosis and treatment of idiopathic pulmonary fibrosis, and reference materials. Conclusion. The presented clinical guidelines cover current information about the etiology and pathogenesis, clinical manifestations, diagnosis, and treatment of hypersensitivity pneumonitis. These guidelines were approved by the Scientific and Practical Council of the Ministry of Health of the Russian Federation in 2023.

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The authors declare that there are no conflicts of interest present.