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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pulmo</journal-id><journal-title-group><journal-title xml:lang="ru">Пульмонология</journal-title><trans-title-group xml:lang="en"><trans-title>PULMONOLOGIYA</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-0189</issn><issn pub-type="epub">2541-9617</issn><publisher><publisher-name>Scientific and Practical Journal “PULMONOLOGIYA” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18093/0869-0189-2024-4397</article-id><article-id custom-type="elpub" pub-id-type="custom">pulmo-4665</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>«Непонятный» кашель</article-title><trans-title-group xml:lang="en"><trans-title>“Perplexing” cough</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0273-4388</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пономарева</surname><given-names>И. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Ponomareva</surname><given-names>I. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пономарева Ирина Борисовна – к. м. н., доцент кафедры факультетской терапии имени профессора В.Я.Гармаша.</p><p>390026, Рязань, ул. Высоковольтная, 9: тел.: (4912) 97-19-37</p></bio><bio xml:lang="en"><p>Irina B. Ponomareva - Candidate of Medicine, Associate Professor, Department of Faculty Therapy named after Professor V.Ya. Garmash.</p><p>Ul. Vysokovoltnaya 9, Ryazan, 390026; tel.: (4912) 97-19-37</p></bio><email xlink:type="simple">docib@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4445-4480</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Глотов</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Glotov</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Глотов Сергей Иванович – к. м. н., доцент, доцент кафедры факультетской терапии имени профессора В.Я. Гармаша.</p><p>390026, Рязань, ул. Высоковольтная, 9: тел.: (4912) 97-19-37</p></bio><bio xml:lang="en"><p>Sergei I. Glotov - Candidate of Medicine, Associate Professor, Assistant Professor, Department of Faculty Therapy named after Professor V.Ya. Garmash.</p><p>Ul. Vysokovoltnaya 9, Ryazan, 390026; tel.: (4912) 97-19-37</p></bio><email xlink:type="simple">sergeyglot@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8693-4696</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Урясьев</surname><given-names>О. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Uryasev</surname><given-names>O. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Урясьев Олег Михайлович – д. м. н., профессор, заведующий кафедрой факультетской терапии имени профессора В.Я. Гармаша.</p><p>390026, Рязань, ул. Высоковольтная, 9: тел.: (4912) 97-18-02</p></bio><bio xml:lang="en"><p>Oleg M. Uryasev - Doctor of Medicine, Professor, head of Department of faculty therapy named after Professor V. Ya.Garmash.</p><p>Ul. Vysokovoltnaya 9, Ryazan, 390026; tel.: (4912) 97-18-02</p></bio><email xlink:type="simple">uryasev08@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3141-4199</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Берстнева</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Berstneva</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Берстнева Светлана Вячеславовна – к. м. н., доцент, доцент кафедры факультетской терапии имени профессора В.Я. Гармаша.</p><p>390026, Рязань, ул. Высоковольтная, 9: тел.: (4912) 97-19-37</p></bio><bio xml:lang="en"><p>Svetlana V. Berstneva - Candidate of Medicine, Associate Professor, Assistant Professor, Department of Faculty Therapy named after Professor V.Ya. Garmash.</p><p>Ul. Vysokovoltnaya 9, Ryazan, 390026; tel.: (4912) 97-19-37</p></bio><email xlink:type="simple">berst.ru@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3370-7593</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Луняков</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lunyakov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Луняков Вадим Анатольевич – к. м. н., доцент, доцент кафедры факультетской терапии имени профессора В.Я. Гармаша.</p><p>390026, Рязань, ул. Высоковольтная, 9: тел.: (4912) 97-19-37</p></bio><bio xml:lang="en"><p> (ORCID: https://orcid.org/0000-0002-3370-7593</p><p>Vadim A. Lunyakov - Candidate of Medicine, Associate Professor, Assistant Professor, Department of Faculty Therapy named after Professor V.Ya. Garmash.</p><p>Ul. Vysokovoltnaya 9, Ryazan, 390026; tel.: (4912) 97-19-37</p></bio><email xlink:type="simple">lunyakov62@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Рязанский государственный медицинский университет имени академика И.П. Павлова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of Higher Professional “Ryazan State Medical University”, Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>12</day><month>12</month><year>2024</year></pub-date><volume>34</volume><issue>6</issue><fpage>879</fpage><lpage>886</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Пономарева И.Б., Глотов С.И., Урясьев О.М., Берстнева С.В., Луняков В.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Пономарева И.Б., Глотов С.И., Урясьев О.М., Берстнева С.В., Луняков В.А.</copyright-holder><copyright-holder xml:lang="en">Ponomareva I.B., Glotov S.I., Uryasev O.M., Berstneva S.V., Lunyakov V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.pulmonology.ru/pulm/article/view/4665">https://journal.pulmonology.ru/pulm/article/view/4665</self-uri><abstract><p>Кашель – одна из серьезных проблем практической пульмонологии. Механизмы возникновения кашля разнообразны, а заболевания, протекающие с хроническим кашлевым синдромом, многочисленны. Сложна диагностическая ситуация, связанная с «непонятным», «необъяснимым», «идиопатическим» кашлем.</p><p>Целью настоящего обзора явилось рассмотрение основных механизмов формирования «непонятного» кашля, вариантов течения, алгоритма ведения пациентов с трудноизлечимым кашлем, а также новых методов лечения.</p><p>Заключение. Хронический «непонятный» кашель нарушает качество жизни пациентов, снижает их работоспособность. Знание механизмов его возникновения, способствует повышению эффективности терапии.</p></abstract><trans-abstract xml:lang="en"><p>Cough is a serious problem of practical pulmonology. The mechanisms of cough occurrence are diverse and numerous diseases are associated with chronic cough syndrome. The diagnosis can be challenging because of a “perplexing”, “unexplained”, or “idiopathic” cough.</p><p>The aim of the review was to consider the main underlying mechanisms of the “perplexing” cough, its potential course, an algorithm for managing patients with the persistent cough, and new treatment methods.</p><p>Conclusion. Chronic “perplexing” cough disrupts the patient’s quality of life and reduces their performance. Unveiling the mechanisms of its development may increase the treatment efficacy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>кашель</kwd><kwd>«непонятный» кашель</kwd><kwd>«идиопатический» кашель</kwd><kwd>кашлевая гиперчувствительность</kwd><kwd>речевая терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cough</kwd><kwd>“perplexing” cough</kwd><kwd>“idiopathic” cough</kwd><kwd>cough hypersensitivity</kwd><kwd>speech therapy</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование выполнялось за счет средств бюджета Федерального государственного бюджетного образовательного учреждения высшего образования «Рязанский государственный медицинский университет имени академика И.П. Павлова» Министерства здравоохранения Российской Федерации</funding-statement><funding-statement xml:lang="en">The study was carried out at the expense of the budget of the Federal State Budgetary Educational Institution of Higher Professional “Ryazan State Medical University”, Ministry of Healthcare of the Russian Federation</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Чучалин А.Г., Абросимов В.Н. Кашель. М.: ГЭОТАР-Медиа; 2016. Доступно на: https://www.rosmedlib.ru/book/ISBN9785970437285.html [Дата обращения: 04.10.23].</mixed-citation><mixed-citation xml:lang="en">Chuchalin A.G., Abrosimov V.N. [Cough]. Moscow: GEOTAR-Media; 2016. 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