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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pulmo</journal-id><journal-title-group><journal-title xml:lang="ru">Пульмонология</journal-title><trans-title-group xml:lang="en"><trans-title>PULMONOLOGIYA</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-0189</issn><issn pub-type="epub">2541-9617</issn><publisher><publisher-name>Scientific and Practical Journal “PULMONOLOGIYA” LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pulmo-462</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Солитарная фиброзная опухоль грудной полости</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Двораковская</surname><given-names>И. В.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., ведущий научный сотрудник НИИ пульмонологии ГБОУ ВПО "СПбГМУ им. акад. И.П.Павлова" Минздрава России; тел.: (921) 7919978</p></bio><email xlink:type="simple">i_dvorakovskaya@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ариэль</surname><given-names>Б. М.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., профессор ФГБУ "СанктПетербургский НИИ фтизиопульмонологии" Минздрава России, член консультативнометодического экспертного совета патологоанатомической службы СанктПетербурга при СПб ГБУЗ "Городское патологоанатоми ческое бюро"; тел.: (911) 7008424</p></bio><email xlink:type="simple">arielboris@rambler.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Платонова</surname><given-names>И. С.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к. м. н., ст. научный сотрудник НИИ пульмонологии ГБОУ ВПО "СПбГМУ им. акад. И.П.Павлова" Минздрава России; тел.: (921) 6366063</p></bio><email xlink:type="simple">is_platonova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мазитова</surname><given-names>Ф. М.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врачпатологоанатом лаборатории патоморфологии ФГБУ "СанктПетербургский НИИ фтизиопульмонологии" Минздрава России; тел.: (965) 0172487</p></bio><email xlink:type="simple">lab_immun@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мосин</surname><given-names>И. В.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., профессор ФГБУ "СанктПетербургский НИИ фтизиопульмонологии" Минздрава России; тел.: (921)9177603;</p></bio><email xlink:type="simple">ivmosin@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яблонский</surname><given-names>П. К.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., профессор ФГБУ "СанктПетербургский НИИ фтизиопульмонологии" Минздрава России; тел.:(901) 3004857</p></bio><email xlink:type="simple">piotr_yablonskii@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>НИИ пульмонологии ГБОУ ВПО "Санкт+Петербургский государственный медицинский университет им. акад. И.П.Павлова" Минздрава России: 197022, Санкт+Петербург, ул. Рентгена, 12</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>НИИ пульмонологии ГБОУ ВПО "Санкт+Петербургский государственный медицинский университет им. акад. И.П.Павлова" Минздрава России: 197022, Санкт+Петербург, ул. Рентгена, 12&#13;
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Санкт+Петербургское ГБУЗ "Городское патологоанатомическое бюро": 194354, Санкт+Петербург, Учебный пер., 5</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-3"><institution>ФГБУ "Санкт+Петербургский научно+исследовательский институт фтизиопульмонологии" Минздрава России: 191036, Санкт+Петербург, Лиговский пр., 2–4</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>28</day><month>10</month><year>2014</year></pub-date><volume>0</volume><issue>5</issue><fpage>20</fpage><lpage>26</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Двораковская И.В., Ариэль Б.М., Платонова И.С., Мазитова Ф.М., Мосин И.В., Яблонский П.К., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Двораковская И.В., Ариэль Б.М., Платонова И.С., Мазитова Ф.М., Мосин И.В., Яблонский П.К.</copyright-holder><copyright-holder xml:lang="en">Двораковская И.В., Ариэль Б.М., Платонова И.С., Мазитова Ф.М., Мосин И.В., Яблонский П.К.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.pulmonology.ru/pulm/article/view/462">https://journal.pulmonology.ru/pulm/article/view/462</self-uri><abstract><p>Приводятся результаты наблюдений больных (n = 15) с солитарными фиброзными опухолями (СФО). Отмечается, что в большинстве случаев заболевание протекало бессимптомно, опухоли были выявлены при рентгенологическом исследовании, проводившемся по иному поводу, будучи диагностированы как периферические опухоли легких с плевральным выпотом. Выявлены доброкачественные (n = 12) и злокачественные (n = 3) СФО. И те и другие различались по микроскопической картине и пролиферативной активности, более высокой в злокачественных СФО, однако установлен аналогичный иммуногистохимический профиль с экспрессией СD34, CD99, bcl2. С учетом гистологической картины опухоли квалифицировались как СФО 3го типа (клеточного), для которого характерно наличие клеток вытянутой формы, образующих муаровые структуры. В гистогенетическом плане СФО рассматриваются как типичные производные мезотелия, т. е. тканевой структуры с особым типом роста, не являющейся ни соединительной тканью, ни эпителием в обычном смысле слова.</p></abstract><kwd-group xml:lang="ru"><kwd>легкие</kwd><kwd>плевра</kwd><kwd>опухоль</kwd><kwd>гистология</kwd><kwd>иммуногистохимическое исследование.</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Wagner E. Das tuberkelahnliche Lymphadenom (der cytogene oder retikulirte Tuberkel). Leipzig Arch. Heilk. 1870; 11: 497.</mixed-citation><mixed-citation xml:lang="en">Wagner E. Das tuberkelahnliche Lymphadenom (der cytogene oder retikulirte Tuberkel). Leipzig Arch. Heilk. 1870; 11: 497.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Robertson H. (1924). Cit: Golovin D.I. (20).</mixed-citation><mixed-citation xml:lang="en">Robertson H. (1924). Cit: Golovin D.I. (20).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Opanasenko N.S., Liskina I.V., Tereshkovich A.V. Pleural fibrosis with development of a large fibroma of the right lungcomplicated with pleural effusion (an unusual case of disseminated pleural solitary fibrous tumor). Ukrains'kiy pul'monologichniy zhurnal. 2004; 4: 51–54 (in Ukrainian).</mixed-citation><mixed-citation xml:lang="en">Opanasenko N.S., Liskina I.V., Tereshkovich A.V. Pleural fibrosis with development of a large fibroma of the right lungcomplicated with pleural effusion (an unusual case of disseminated pleural solitary fibrous tumor). Ukrains'kiy pul'monologichniy zhurnal. 2004; 4: 51–54 (in Ukrainian).</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Zenger V.G., Synebogov S.V., Kadyrova E.V. Solitary fibrous mesothelial tumor of maxiliary sinus and nasal cavity. Vestnik otorinolaringologii. 2002; 6: 53 (in Russian).</mixed-citation><mixed-citation xml:lang="en">Zenger V.G., Synebogov S.V., Kadyrova E.V. Solitary fibrous mesothelial tumor of maxiliary sinus and nasal cavity. Vestnik otorinolaringologii. 2002; 6: 53 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Mukhamedzhanov D.Zh., Serkov S.V., Bocharov A.A. et al. Solitary fibrous tumor (a case report). Meditsinskaya vizual izatsiya. 2008; 6: 24–30 (in Russian).</mixed-citation><mixed-citation xml:lang="en">Mukhamedzhanov D.Zh., Serkov S.V., Bocharov A.A. et al. Solitary fibrous tumor (a case report). Meditsinskaya vizual izatsiya. 2008; 6: 24–30 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Cardillo G., Facciolo F., Cavazzana A.O. et al. Localized (solitary) fibrous tumors of the pleura: an analysis of 55 patients. Ann. Thorac. Surg. 2000; 70: 1808–1812.</mixed-citation><mixed-citation xml:lang="en">Cardillo G., Facciolo F., Cavazzana A.O. et al. Localized (solitary) fibrous tumors of the pleura: an analysis of 55 patients. Ann. Thorac. Surg. 2000; 70: 1808–1812.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Pavlov K.A., Dubova E.A., Shchegolev A.I., Karmazanov skiy G.G. Solitary fibrous tumor of the pleura. Diagnosticheskaya interventsionnaya radiologiya. 2008; 2 (4): 103–112 (in Russian).</mixed-citation><mixed-citation xml:lang="en">Pavlov K.A., Dubova E.A., Shchegolev A.I., Karmazanov skiy G.G. Solitary fibrous tumor of the pleura. Diagnosticheskaya interventsionnaya radiologiya. 2008; 2 (4): 103–112 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Briselli M., Mark E.J., Dickersin G.R. Solitary fibroustumors of the pleura: eight new cases and review of 360 cases in the literature. Cancer.1981; 47: 2678–2689.</mixed-citation><mixed-citation xml:lang="en">Briselli M., Mark E.J., Dickersin G.R. Solitary fibroustumors of the pleura: eight new cases and review of 360 cases in the literature. Cancer.1981; 47: 2678–2689.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Vishnya Yu.E., Grinberg L.M. Solitary fibrous tumor of the pleura (a review). Ural'skiy meditsinskiy zhurnal. 2012; 13: 78–82 (in Russian).</mixed-citation><mixed-citation xml:lang="en">Vishnya Yu.E., Grinberg L.M. Solitary fibrous tumor of the pleura (a review). Ural'skiy meditsinskiy zhurnal. 2012; 13: 78–82 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Leenman E.E., Popov S.D., Dvorakovskaya I.V. et al. Solitary fibrous tumor: clinical, morphological and immunohis tochemical analysis. Voprosy onkologii. 2006; 52 (6): 624– 632 (in Russian).</mixed-citation><mixed-citation xml:lang="en">Leenman E.E., Popov S.D., Dvorakovskaya I.V. et al. Solitary fibrous tumor: clinical, morphological and immunohis tochemical analysis. Voprosy onkologii. 2006; 52 (6): 624– 632 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">TapiasVargas L.F., SantamariaAriza C.M., TapiasVargas L. et al. Malignant solitary fibrous tumor of the pleura: report of two cases. Circulation. 2012; 80: 270–273.</mixed-citation><mixed-citation xml:lang="en">TapiasVargas L.F., SantamariaAriza C.M., TapiasVargas L. et al. Malignant solitary fibrous tumor of the pleura: report of two cases. Circulation. 2012; 80: 270–273.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Sekiya M.I., Yoshimi K., Muraki K. et al. Solitary fibrous tumor of the pleura. Ultrasonographic imaging findings of 3 cases. Respir. Investig. 2013; 51: 200–204.</mixed-citation><mixed-citation xml:lang="en">Sekiya M.I., Yoshimi K., Muraki K. et al. Solitary fibrous tumor of the pleura. Ultrasonographic imaging findings of 3 cases. Respir. Investig. 2013; 51: 200–204.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Bernardini F.B., de Concillis C., Schneider S. et al. Solitary fibrous tumor of the orbit: is it rare? Report of a case series and review of the literature. Ophthalmology. 2003; 110;1442–1448.</mixed-citation><mixed-citation xml:lang="en">Bernardini F.B., de Concillis C., Schneider S. et al. Solitary fibrous tumor of the orbit: is it rare? Report of a case series and review of the literature. Ophthalmology. 2003; 110;1442–1448.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Brunori A., Cerasoli S., Donati R. et al. Solitary fibroustumor of the meninges: two new cases and review of the literature. Surg. Neurol. 1999; 51: 636–640.</mixed-citation><mixed-citation xml:lang="en">Brunori A., Cerasoli S., Donati R. et al. Solitary fibroustumor of the meninges: two new cases and review of the literature. Surg. Neurol. 1999; 51: 636–640.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Fukunaga M., Naganuma H., Nikaido T. et al. Extrapleural solitary fibrous tumor: a report of seven cases. Mod. Pathol. 1997; 10: 443–450.</mixed-citation><mixed-citation xml:lang="en">Fukunaga M., Naganuma H., Nikaido T. et al. Extrapleural solitary fibrous tumor: a report of seven cases. Mod. Pathol. 1997; 10: 443–450.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Fletcher D.M. The evolving classification of soft tissue tumours: an update baswd on the new WHO classification. Histopathology. 2006; 48: 3–12.</mixed-citation><mixed-citation xml:lang="en">Fletcher D.M. The evolving classification of soft tissue tumours: an update baswd on the new WHO classification. Histopathology. 2006; 48: 3–12.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Granville L., Laga A.C., Allen T.C. et al. Review and update of uncommon primary pleural tumors. A practical approach to diagnosis. Arch. Pathol. Lab. Med. 2005; 129: 1428–1443.</mixed-citation><mixed-citation xml:lang="en">Granville L., Laga A.C., Allen T.C. et al. Review and update of uncommon primary pleural tumors. A practical approach to diagnosis. Arch. Pathol. Lab. Med. 2005; 129: 1428–1443.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Ordonez N.G. Localized (solitary) fibrous tumor of the pleura. Adv. Anat. Pathol. 2000; 7: 327–340.</mixed-citation><mixed-citation xml:lang="en">Ordonez N.G. Localized (solitary) fibrous tumor of the pleura. Adv. Anat. Pathol. 2000; 7: 327–340.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Tochigi N.I., Attanoos R., Chirieac L.R. et al. p16 deletion in sarcomatoid tumors of the lung and pleura. Arch. Pathol. Lab. Med. 2013; 137: 632–636.</mixed-citation><mixed-citation xml:lang="en">Tochigi N.I., Attanoos R., Chirieac L.R. et al. p16 deletion in sarcomatoid tumors of the lung and pleura. Arch. Pathol. Lab. Med. 2013; 137: 632–636.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Golovin D.I. Atlas of Human Tumors. Leningrad: Meditsina; 1975 (in Russian.)</mixed-citation><mixed-citation xml:lang="en">Golovin D.I. Atlas of Human Tumors. Leningrad: Meditsina; 1975 (in Russian.)</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Pikin O.V., Osipov V.V., Belous T.A. et al. Solitary fibroustumor of the pleura mimicking pulmonary metastasis from breast carcinoma. Onkologiya. Zhurnal im. P.A.Gertsena. 2012; 3: 58–60 (in Russian).</mixed-citation><mixed-citation xml:lang="en">Pikin O.V., Osipov V.V., Belous T.A. et al. Solitary fibroustumor of the pleura mimicking pulmonary metastasis from breast carcinoma. Onkologiya. Zhurnal im. P.A.Gertsena. 2012; 3: 58–60 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Khlopin N.G. General Biological and Experimental Basis of Histology. Moscow–Leningrad: Izd. AN SSSR; 1946 (inRussian).</mixed-citation><mixed-citation xml:lang="en">Khlopin N.G. General Biological and Experimental Basis of Histology. Moscow–Leningrad: Izd. AN SSSR; 1946 (inRussian).</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Stout A.P., Murray M.R. Localized pleural mesothelioma: investigation of its characteristics and histogenesis by the methods of tissue culture. Arch. Pathol. 1942; 34: 951–964.</mixed-citation><mixed-citation xml:lang="en">Stout A.P., Murray M.R. Localized pleural mesothelioma: investigation of its characteristics and histogenesis by the methods of tissue culture. Arch. Pathol. 1942; 34: 951–964.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Garshin V.G. Inflammatory Hypertrophy of the Epithelium and its Biological Role for Carcinogenesis. Moscow–Leningrad; 1939 (in Russian).</mixed-citation><mixed-citation xml:lang="en">Garshin V.G. Inflammatory Hypertrophy of the Epithelium and its Biological Role for Carcinogenesis. Moscow–Leningrad; 1939 (in Russian).</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
