<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pulmo</journal-id><journal-title-group><journal-title xml:lang="ru">Пульмонология</journal-title><trans-title-group xml:lang="en"><trans-title>PULMONOLOGIYA</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-0189</issn><issn pub-type="epub">2541-9617</issn><publisher><publisher-name>Scientific and Practical Journal “PULMONOLOGIYA” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18093/0869-0189-2011-0-6-62-68</article-id><article-id custom-type="elpub" pub-id-type="custom">pulmo-419</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Особенности течения пневмонии при пандемическом гриппе А / Н1N1 / 09</article-title><trans-title-group xml:lang="en"><trans-title>Character features of community-acquired pneumonia during the pandemic influenza A / N1N1 / 2009</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лещенко</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Leshchenko</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д. м. н., проф. кафедры фтизиатрии и пульмонологии ФПК и ПП </p><p>620109, Екатеринбург, ул. Заводская, 29. Тел. / факс: (343) 246-44-75, (343) 246-44-75.</p></bio><email xlink:type="simple">leshchenkoiv@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кривоногов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Krivonogov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-пульмонолог</p><p>620109, Екатеринбург, ул. Заводская, 29. Тел. / факс: (343) 242-48-42, (343) 246-44-75.</p></bio><email xlink:type="simple">angedonia35@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ГОУ ВПО "Уральская государственная медицинская академия" Минздравсоцразвития России; Медицинское объединение "Новая больница"</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>Медицинское объединение "Новая больница"</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>28</day><month>12</month><year>2011</year></pub-date><volume>0</volume><issue>6</issue><fpage>62</fpage><lpage>68</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лещенко И.В., Кривоногов А.В., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Лещенко И.В., Кривоногов А.В.</copyright-holder><copyright-holder xml:lang="en">Leshchenko I.V., Krivonogov A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.pulmonology.ru/pulm/article/view/419">https://journal.pulmonology.ru/pulm/article/view/419</self-uri><abstract><p>Резюме. Изучали особенности течения и осложнения внебольничной пневмонии (ВП) при пандемическом гриппе А / Н1N1 / 09 на основании клинико-лабораторных и рентгенологических данных. В исследовании участвовали 250 больных, которых распределили по 4 группам: 1-я группа – 57 пациентов с неосложненной ВП, 2-я – 124 больных с ВП и синдромом системной воспалительной реакции, 3-я – 53 пациента с ВП, осложненной тяжелым сепсисом, и 4-я – 16 больных ВП с септическим шоком. У 225 больных (90,0 %) установлено 2-стороннее поражение легочной ткани. 193 (77,2 %) пациента нуждались в кислородотерапии, 108 из них (56 %) госпитализированы в отделение реанимации и интенсивной терапии, у 15,6 % проводилась искусственная вентиляция легких. Общая летальность составила 10,4 %, среди больных с ожирением – 30,0 %.</p></abstract><trans-abstract xml:lang="en"><p>Summary. Course and complications of community-acquired pneumonia (CAP) during the pandemic influenza A / N1N1 / 2009 were studied based on clinical, laboratory and radiology data. The study involved 250 patients, of them 57 patients with uncomplicated CAP (the 1st group), 124 patients with CAP and the systemic inflammatory response syndrome (SIRS) (the 2nd group), 53 patients with CAP and severe sepsis (the 3rd group), and 16 patients with CAP and septic shock (the 4th group). All patients received antiviral, antibacterial and symptomatic therapy; 193 (77.2 %) patients needed supplemental oxygen, 108 (56 %) were admitted to ICU, 15.6 % of patients needed mechanical ventilation. Bilateral lung injury was diagnosed in 225 patients (90.0 %). Overall mortality was 10.4 %, mortality in obese patients was 30.0 %.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>внебольничная пневмония</kwd><kwd>пандемический грипп А / Н1N1 / 09</kwd><kwd>клиника</kwd><kwd>осложнения</kwd><kwd>лечение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>community-acquired pneumonia</kwd><kwd>pandemic influenza А / Н1N1 / 2009</kwd><kwd>clinical course</kwd><kwd>complications</kwd><kwd>treatment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Rai S., Rane S., Kumar S. et al. Swine-origin influenza A / H1N1 / 09: An update. Bombay Hosp. J. 2009; 51 (3): 331–341.</mixed-citation><mixed-citation xml:lang="en">Rai S., Rane S., Kumar S. et al. Swine-origin influenza A / H1N1 / 09: An update. Bombay Hosp. J. 2009; 51 (3): 331–341.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Bautista E., Chotpitayasunondh T., Gao Z. et al. Clinical aspects of pandemic 2009 influenza a / H1N1 / virus infection. N. Engl. J. Med. 2010; 362: 1708–1719.</mixed-citation><mixed-citation xml:lang="en">Bautista E., Chotpitayasunondh T., Gao Z. et al. Clinical aspects of pandemic 2009 influenza a / H1N1 / virus infection. N. Engl. J. Med. 2010; 362: 1708–1719.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Borgatta B., Rello J. The 2009 influenza A / H1N1 / pandemic-a blast from the past. US Respir. Dis. 2010; 6: 65–70.</mixed-citation><mixed-citation xml:lang="en">Borgatta B., Rello J. The 2009 influenza A / H1N1 / pandemic-a blast from the past. US Respir. Dis. 2010; 6: 65–70.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Клинико-организационное руководство. Порядок оказания медицинской помощи при инфекции, вызванной пандемическим вирусом гриппа A / H1N1 / Калифорния / 04 / 09, жителям Свердловской области. Екатеринбург; 2009.</mixed-citation><mixed-citation xml:lang="en">Клинико-организационное руководство. Порядок оказания медицинской помощи при инфекции, вызванной пандемическим вирусом гриппа A / H1N1 / Калифорния / 04 / 09, жителям Свердловской области. Екатеринбург; 2009.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Bone R.C., Balk R.A., Cerra F.B., the ACCP / SCCM Consensus Conference Committee. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 1992; 101: 1644–1655. Updated: Jul. 28, 2009 [Medline].</mixed-citation><mixed-citation xml:lang="en">Bone R.C., Balk R.A., Cerra F.B., the ACCP / SCCM Consensus Conference Committee. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 1992; 101: 1644–1655. Updated: Jul. 28, 2009 [Medline].</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Bone R.C. Systemic inflammatory response syndrome: a unifying concept of systemic inflammation. In: Fein A., Abraham A. et al. Sepsis and multiorgan failure. Philadelphia, Pa: Lippincott, Williams &amp; Wilkins; 1997. 1–10.</mixed-citation><mixed-citation xml:lang="en">Bone R.C. Systemic inflammatory response syndrome: a unifying concept of systemic inflammation. In: Fein A., Abraham A. et al. Sepsis and multiorgan failure. Philadelphia, Pa: Lippincott, Williams &amp; Wilkins; 1997. 1–10.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Dellinger R.P. Levy M.M., Carlet J.M. et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intens. Care Med. 2008; 34 (1): 17–60.</mixed-citation><mixed-citation xml:lang="en">Dellinger R.P. Levy M.M., Carlet J.M. et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intens. Care Med. 2008; 34 (1): 17–60.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Внебольничная пневмония у взрослых: Практические рекомендации по диагностике, лечению и профилактике: Пособие для врачей. М.; 2010.</mixed-citation><mixed-citation xml:lang="en">Внебольничная пневмония у взрослых: Практические рекомендации по диагностике, лечению и профилактике: Пособие для врачей. М.; 2010.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Гланц С. Медико-биологическая статистика. М.: Практика, 1999.</mixed-citation><mixed-citation xml:lang="en">Гланц С. Медико-биологическая статистика. М.: Практика, 1999.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">WHO Guidelines for pharmacological management of pandemic (H1N1) 2009 influenza and other influenza viruses. Geneva: World Health Organization, 2009.</mixed-citation><mixed-citation xml:lang="en">WHO Guidelines for pharmacological management of pandemic (H1N1) 2009 influenza and other influenza viruses. Geneva: World Health Organization, 2009.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
