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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pulmo</journal-id><journal-title-group><journal-title xml:lang="ru">Пульмонология</journal-title><trans-title-group xml:lang="en"><trans-title>PULMONOLOGIYA</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-0189</issn><issn pub-type="epub">2541-9617</issn><publisher><publisher-name>Scientific and Practical Journal “PULMONOLOGIYA” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18093/0869-0189-2022-32-6-806-833</article-id><article-id custom-type="elpub" pub-id-type="custom">pulmo-4155</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ РЕКОМЕНДАЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL GUIDELINES</subject></subj-group></article-categories><title-group><article-title>Саркоидоз: федеральные клинические рекомендации по диагностике и лечению</article-title><trans-title-group xml:lang="en"><trans-title>Sarcoidosis: federal clinical guidelines for diagnosis and treatment</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6808-5528</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чучалин</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Chuchalin</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чучалин Александр Григорьевич – доктор медицинских наук, профессор, академик  Российской  академии  наук, заведующий кафедрой  госпитальной терапии педиатрического факультета РНИМУ  им. Н.И. Пирогова МЗ РФ; председатель  правления Российского респираторного общества.</p><p>117997, Москва, ул. Островитянова, 1</p><p>тел.: (499) 780-08-50</p><p>SPIN-код: 7742-2054</p></bio><bio xml:lang="en"><p>Alexander G. Chuchalin - Doctor of Medicine, Professor, Academician of Russian Academy of Sciences, Head of Department of Hospital Internal Medicine, Pediatric  Faculty,  Pirogov Russian National  Research  Medical  University (Pirogov Medical University),  Healthcare Ministry of Russia; Chairman of the Executive Board of Russian Respiratory Society.</p><p>Ostrovityanova ul. 1, Moscow, 117997</p><p>tel.: (499) 780-08-50</p><p>SPIN: 7742-2054</p></bio><email xlink:type="simple">pulmomoskva@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5999-2150</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Авдеев</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Avdeev</surname><given-names>S. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Авдеев Сергей Николаевич – доктор медицинских наук, профессор, академик  Российской академии наук, заведующий кафедрой пульмонологии Института клинической медицины имени Н.В. Склифосовского ПМГМУ им. И.М. Сеченова МЗ РФ (Сеченовский Университет); ведущий научный  сотрудник НИИ пульмонологии ФМБА.</p><p>119991, Москва, ул. Трубецкая, 8, стр. 2; 115682, Москва, Ореховый бульвар, 28</p><p>тел.: (495) 708-35-76</p><p>SPIN-код: 1645-5524</p></bio><bio xml:lang="en"><p>Sergey N. Avdeev - Doctor  of Medicine,  Professor, Academician  of Russian Academy of Sciences, Head of the Department of Pulmonology, N.V. Sklifosovsky Institute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University of the Ministry of Health  of the Russian Federation (Sechenov University); Leading Researcher,  Federal Pulmonology  Research Institute, Federal Medical and Biological Agency of Russia.</p><p>Trubetskaya ul. 8, build. 2, Moscow, 119991; Orekhovyy bul’var 28,  Moscow, 115682</p><p>tel.: (495) 708-35-76</p><p>SPIN-code: 1645-5524</p></bio><email xlink:type="simple">serg_avdeev@list.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4044-674X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Айсанов</surname><given-names>З. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Aisanov</surname><given-names>Z. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Айсанов Заурбек Рамазанович – доктор медицинских наук, профессор кафедры пульмонологии.</p><p>117997, Москва, ул. Островитянова, 1</p><p>тел.: (495) 965-34-66</p></bio><bio xml:lang="en"><p>Zaurbek R. Aisanov - Doctor  of Medicine,  Professor, Department of Pulmonology, Pirogov Russian National  Research  Medical University (Pirogov Medical University),  Healthcare Ministry of Russia.</p><p>Ostrovityanova ul. 1, Moscow, 117997</p><p>tel.: (495) 965-34-66</p></bio><email xlink:type="simple">aisanov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5032-5442</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баранова</surname><given-names>О. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Baranova</surname><given-names>O. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Баранова Ольга Петровна – кандидат медицинских наук, старший  научный  сотрудник  Научно-исследовательского института  интерстициальных и орфанных заболеваний легких.</p><p>197022, Санкт-Петербург, ул. Льва Толстого, 6–8</p><p>тел.: (812) 499-68-40</p></bio><bio xml:lang="en"><p>Olga P. Baranova - Candidate  of Medicine,  Senior Researcher,  Research Institute of Interstitial  and Orphan  Lung Diseases, Federal  State Budgetary Educational  Institution of Higher Education  “Academician I.P.Pavlov First St. Petersburg State Medical University” of the Ministry of Healthcare of Russian Federation.</p><p>L’va Tolstogo ul. 6 – 8, Saint-Petersburg, 197089</p><p>tel.: (812) 499-68-40</p></bio><email xlink:type="simple">dr_baranova@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7423-5433</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Борисов</surname><given-names>С. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Borisov</surname><given-names>S. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Борисов Сергей Евгеньевич – доктор медицинских наук, профессор, заместитель директора по научно-клинической работе.</p><p>107076, Москва, ул. Стромынка, 10</p><p>тел.: (903) 777-06-56</p></bio><bio xml:lang="en"><p>Sergey E. Borisov - Doctor of Medicine, Professor, Deputy Director for Scientific and Clinical Work, State Budgetary Healthcare Institution  of the Moscow City “Moscow City Scientific and Practical Center for Combating Tuberculosis, Moscow City Department of Healthcare.</p><p>Stromynka ul. 10, Moscow, 107076</p><p>tel.: (903) 777-06-56</p></bio><email xlink:type="simple">sebarsik@gmail.com</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0547-3686</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Геппе</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Geppe</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Геппе Наталия Анатольевна – доктор медицинских наук, профессор, заведующая кафедрой детских болезней института клинической медицины.</p><p>119991, Москва,  ул. Трубецкая, 8, стр. 2</p><p>тел.: (499) 248-44-22</p></bio><bio xml:lang="en"><p>Natal’ya A. Geppe - Doctor of Medicine, Professor, Head of Department of Pediatric Diseases, Therapeutic Faculty, Federal State Autonomous Educational Institution of Higher Education  I.M. Sechenov First Moscow State Medical University of the Ministry of Health  of the Russian Federation (Sechenov University).</p><p>Trubetskaya ul. 8, build. 2, Moscow, 119991</p><p>tel.: (499) 248-44-22</p></bio><email xlink:type="simple">geppe@mail.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5028-5276</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Визель</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vizel’</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Визель Александр Андреевич – доктор медицинских наук, профессор, заведующий кафедрой фтизиопульмонологии.</p><p>420012, Республика Татарстан, Казань, ул. Бутлерова, 49</p><p>тел.: (987) 296-25-99</p><p>SPIN:  5918-5465; Author ID: 195447</p></bio><bio xml:lang="en"><p>Aleksandr A. Vizel’ - Doctor  of Medicine, Professor,  Head  of Department of Phthisiopulmonology and Pulmonology, Kazan’ State Medical University, Healthcare Ministry of Russia.</p><p>Butlerova ul. 49, Kazan’, 420012, Tatarstan Republic</p><p>tel.: (987) 296-25-99</p><p>SPIN:  5918-5465; Author ID: 195447</p></bio><email xlink:type="simple">lordara@inbox.ru</email><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8855-8177</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Визель</surname><given-names>И. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Vizel’</surname><given-names>I. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Визель Ирина Юрьевна – доктор медицинских наук, профессор Российской академии естествознания, доцент кафедры  фтизиопульмонологии.</p><p>420012, Республика Татарстан, Казань, ул. Бутлерова, 49</p><p>тел.: (917) 903-91-13</p></bio><bio xml:lang="en"><p>Irina Yu. Vizel’ - Doctor  of Medicine,  Professor, Russian Academy of Natural Sciences, Associate Professor, Department of Phthisiopulmonology and Pulmonology, Kazan’ State Medical University, Healthcare  Ministry of Russia.</p><p>Butlerova ul. 49, Kazan’, 420012, Tatarstan Republic</p><p>tel.: (917) 903-91-13</p></bio><email xlink:type="simple">tatpulmo@mail.ru</email><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0934-7313</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайцев</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaicev</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зайцев Андрей Алексеевич – доктор медицинских наук, профессор, главный пульмонолог.</p><p>105094, Москва, Госпитальная пл., 3</p><p>тел.: (495) 263-10-47</p><p>SPIN-код: 6549-5154, Author ID: 217005</p></bio><bio xml:lang="en"><p>Andrey A. Zaicev - Doctor  of Medicine, Professor,  Chief Pulmonologist, Main Military Clinical Hospital  named  after academician N.N. Burdenko, Ministry of Defense of the Russian Federation.</p><p>Gospital’naya pl. 3, Moscow, 105229</p><p>SPIN: 6549-5154, Author ID: 217005</p></bio><email xlink:type="simple">a-zaicev@yandex.ru</email><xref ref-type="aff" rid="aff-7"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5228-7793</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кравченко</surname><given-names>Н. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Kravchenko</surname><given-names>N. Y.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кравченко Наталья Юрьевна – врач-пульмонолог, заведующая организационно-методическим отделом по аллергологии-иммунологии и пульмонологии.</p><p>115088, Москва, ул. Шарикоподшипниковская, 9</p><p>тел.: (916) 118-32-19</p></bio><bio xml:lang="en"><p>Natalya Y. Kravchenko - Pulmonologist,  Head of the Organizational and Methodological Department for Allergology-Immunology and Pulmonology, State Budgetary Institution “Scientific Research Institute of Health Organization and Medical Management, Moscow City Department of Healthcare”.</p><p>Sharikopodshipnikovskaya ul. 9, Moscow, 115088</p><p>tel.: (916) 118-32-19</p></bio><email xlink:type="simple">pulmokongress@mail.ru</email><xref ref-type="aff" rid="aff-8"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5191-445X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Илькович</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Ilkovich</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Илькович Михаил Михайлович – доктор медицинских наук, профессор, заведующий  кафедрой  пульмонологии факультета  последипломного образования, директор  Научно-исследовательского института  интерстициальных и орфанных заболеваний легких.</p><p>197022, Санкт-Петербург, ул. Льва Толстого, 6–8</p><p>тел.: (812) 338-78-32</p><p>SPIN-код: 6239-7007, Author ID: 665454</p></bio><bio xml:lang="en"><p>Mikhail M. Ilkovich - Doctor  of Medicine,  Professor, Head of pulmonology Department of Postgraduate School, Director of Interstitial and Orphan Lung Diseases Research Institute, Academician I.P. Pavlov First St. Petersburg State Medical University of the Ministry of Healthcare of Russian Federation.</p><p>L’va Tolstogo ul. 6 – 8, Saint-Petersburg, 197089</p><p>tel.: (812) 338-78-32</p><p>SPIN-код: 6239-7007, Author ID: 665454</p></bio><email xlink:type="simple">mih.ilkovich@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3091-4677</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ловачева</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lovacheva</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ловачева Ольга Викторовна – доктор медицинских наук, профессор, главный научный сотрудник отдела дифференциальной диагностики и лечения туберкулеза и сочетанных  инфекций.</p><p>127473, Москва, ул. Достоевского, 4, корп. 2</p><p>тел.: (495) 681-84-22</p></bio><bio xml:lang="en"><p>Ol’ga V. Lovacheva - Doctor of Medicine, Professor, Chief Researcher, Department of Differential Diagnosis and Treatment of Tuberculosis and Combined Infections,  Federal State Budgetary Institution “National Medical Research Center for Phthisiopulmonology and Infectious Diseases”, Ministry of Healthcare of Russian Federation.</p><p>Dostoyevskogo ul. 4, build. 2, Moscow, 127473</p><p>tel.: (495) 681-84-22</p></bio><email xlink:type="simple">olga.lovacheva@yandex.ru</email><xref ref-type="aff" rid="aff-9"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2686-8284</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малахов</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Malakhov</surname><given-names>A. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Малахов Александр Борисович – доктор медицинских наук, профессор кафедры  детских болезней.</p><p>119991, Москва, ул. Трубецкая, 8, стр. 2</p><p>тел.: (985) 970-73-11</p></bio><bio xml:lang="en"><p>Aleksandr B. Malakhov - Doctor of Medicine,  Professor, Department of Pediatric Diseases, I.M. Sechenov First Moscow State Medical University of the Ministry of Health  of the Russian Federation (Sechenov  University).</p><p>Trubetskaya ul. 8, build. 2, Moscow, 119991,</p><p>tel.: (985) 970-73-11</p></bio><email xlink:type="simple">alexis4591m@mail.ru</email><xref ref-type="aff" rid="aff-10"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6128-5914</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Малявин</surname><given-names>A. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Malyavin</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Малявин Андрей Георгиевич – доктор медицинских наук, профессор кафедры фтизиатрии и пульмонологии.</p><p>127473, Москва, ул. Делегатская, 20, стр. 1</p><p>тел.: (916) 547-83-73</p></bio><bio xml:lang="en"><p>Andrey G. Malyavin - Doctor of Medicine,  Professor, Department of Phthisiology and Pulmonology,  Federal State Budgetary Educational  Institution of the Higher Education “ A.I. Yevdokimov Moscow State University of Medicine and Dentistry”  of the Ministry of Healthcare  of the Russian Federation.</p><p>Delegatskaya ul. 20/1, Moscow, 127473</p><p>tel.: (916) 547-83-73</p></bio><email xlink:type="simple">maliavin@mail.ru</email><xref ref-type="aff" rid="aff-11"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5815-5895</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петров</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrov</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Петров Дмитрий Владимирович – ассистент кафедры пропедевтики внутренних  болезней.</p><p>644043, Омск, ул. Ленина, 12</p><p>тел.: (913) 968-69-47</p></bio><bio xml:lang="en"><p>Dmitriy V. Petrov - Assistant Lecturer, Department of Propaedeutics of Internal Diseases, Omsk State Medical University, Healthcare  Ministry of Russia.</p><p>Lenina ul. 12, Omsk, 644099</p><p>tel.: (913) 968-69-47</p></bio><email xlink:type="simple">dmitrpetrov@bk.ru</email><xref ref-type="aff" rid="aff-12"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0690-3345</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Романов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Romanov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Романов Владимир Викторович – доктор медицинских наук, профессор, заведующий отделом фтизиатрии.</p><p>107564, Москва, Яузская аллея, 2</p><p>тел.: (916) 169-84-60</p></bio><bio xml:lang="en"><p>Vladimir V. Romanov - Doctor of Medicine, Professor, Head of the Department of Phthisiology, Federal State Scientific Institution “Central Research Institute of Tuberculosis”.</p><p>Yauzskaya alleya 2, Moscow, 107564</p><p>tel.: (916) 169-84-60</p></bio><email xlink:type="simple">romanov-vladimir-vik@yandex.ru</email><xref ref-type="aff" rid="aff-13"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8170-3300</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сивокозов</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sivokozov</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сивокозов Илья Владимирович – кандидат медицинских наук, заведующий  отделением  эндоскопии Центра  диагностики и реабилитации заболеваний органов дыхания.</p><p>107564, Москва, Яузская аллея, 2</p><p>тел.: (915) 132-27-89</p></bio><bio xml:lang="en"><p>Ilya V. Sivokozov - Candidate of Medicine, Head of Department of endoscopy, Center  for Diagnosis and Rehabilitation of Respiratory  Diseases, Federal State Scientific Institution “Central  Research Institute of Tuberculosis”.</p><p>Yauzskaya alleya 2, Moscow, 107564</p><p>tel.: (915) 132-27-89</p></bio><email xlink:type="simple">grand63@yandex.ru</email><xref ref-type="aff" rid="aff-13"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8170-1260</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Самсонова</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Samsonova</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Самсонова Мария Викторовна – доктор медицинских наук, заведующая лабораторией патологической  анатомии  и иммунологии НИИ пульмонологии ФМБА России; старший  научный  сотрудник  лаборатории инновационной патоморфологии МКНЦ им. А.С. Логинова ДЗ г. Москвы.</p><p>115682, Москва,  Ореховый бульвар, 28; 111123, Москва, шоссе Энтузиастов, 86</p><p>тел.: (495) 465-58-59</p></bio><bio xml:lang="en"><p>Mariya V. Samsonova - Doctor of Medicine, Head of Laboratory of Pathological Anatomy and Immunology,  Federal Pulmonology Research Institute,  Federal Medical and Biological Agency of Russia, Senior Researcher,  Laboratory of Innovative  Pathomorphology, State Budgetary Institution Moscow Clinical Scientific Center named after Loginov, Moscow City Department of Healthcare.</p><p>Orekhovyy bul’var 28, Moscow, 115682; Shosse Entuziastov 86, Moscow, 111123</p><p>tel.: (495) 465-58-59</p></bio><email xlink:type="simple">samary@mail.ru</email><xref ref-type="aff" rid="aff-14"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0757-6796</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соловьева</surname><given-names>И. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Solovieva</surname><given-names>I. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Соловьева Ирина Павловна – доктор медицинских наук, профессор, заведующая  лабораторией  патологической анатомии.</p><p>119991, Москва, ул. Трубецкая, 8, стр. 2</p><p>тел.: (499) 268-25-26</p></bio><bio xml:lang="en"><p>Irina P. Solovieva - Doctor of Medicine,  Professor, Head of the Laboratory of Pathological  Anatomy,  Federal  State Autonomous  Educational Institution of Higher Education  I.M. Sechenov First Moscow State Medical University of the Ministry of Health  of the Russian Federation (Sechenov  University).</p><p>Trubetskaya ul. 8, build. 2, Moscow, 119991,</p><p>tel.: (499) 268-25-26</p></bio><email xlink:type="simple">cheral12@gmail.com</email><xref ref-type="aff" rid="aff-15"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2985-3379</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Степанян</surname><given-names>И. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Stepanyan</surname><given-names>I. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Степанян Игорь Эмильевич – доктор медицинских наук, профессор, ведущий  научный сотрудник  отдела дифференциальной диагностики туберкулеза и экстракорпоральных методов лечения,  советник  директора.</p><p>107564, Москва, Яузская аллея, 2</p><p>тел.: (499) 169-99-51</p><p>SPIN-code: 8854-5951; Author ID: 443264</p></bio><bio xml:lang="en"><p>Igor’ E. Stepanyan - Doctor of Medicine, Professor, Leading Researcher, Division of Differential Diagnosis of Pulmonary Tuberculosis and Extracorporeal Therapeutic Methods, Federal Central Research Institute of Tuberculosis.</p><p>Yauzskaya alleya 2, Moscow, 107564</p><p>tel.: (499) 169-99-51</p><p>SPIN-code: 8854-5951; Author ID: 443264</p></bio><email xlink:type="simple">drstepanyan@mail.ru</email><xref ref-type="aff" rid="aff-13"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5444-5943</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Терпигорев</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Terpigorev</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Терпигорев Станислав Анатольевич – доктор медицинских наук, профессор, руководитель отделения профессиональной патологии и врачебно-трудовой экспертизы.</p><p>129110, Москва, ул. Щепкина, 61 / 2</p><p>тел.: (495) 681-03-71</p><p>SPIN-code: 9404-3122</p></bio><bio xml:lang="en"><p>Stanislav A. Terpigorev - Doctor of Medicine,  Professor, Head of Department of Occupational Diseases and Medical  Expertise,  M.F. Vladimirskiy  State Moscow Regional Research Clinical Institute.</p><p>Shchepkina ul. 61/2, Moscow, 129110</p><p>tel.: (495) 681-03-71</p></bio><email xlink:type="simple">smith42@yandex.ru</email><xref ref-type="aff" rid="aff-16"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3931-1431</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тюрин</surname><given-names>И. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Tyurin</surname><given-names>I. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тюрин Игорь Евгеньевич – д. м. н., профессор, заведующий кафедрой рентгенологии и радиологии.</p><p>123995, Москва, ул. Баррикадная, 2, стр. 1</p><p>тел.: (903) 758-46-52</p><p>SPINcode: 6499-2398</p></bio><bio xml:lang="en"><p>Igor’ E. Tyurin, Doctor of Medicine, Professor, Head of Department of Radiology</p><p>ul. Barrikadnaya 2/1, Moscow, 123995</p><p>tel.: (903) 758-46-52</p><p>SPIN-code: 6499-2398</p></bio><email xlink:type="simple">igortyurin@gmail.com</email><xref ref-type="aff" rid="aff-17"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1604-3446</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Французевич</surname><given-names>Л. Я.</given-names></name><name name-style="western" xml:lang="en"><surname>Frantsuzevich</surname><given-names>L. Ya.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Французевич Лайне Яновна – ассистент кафедры пульмонологии факультета дополнительного профессионального образования Федерального образования «Российский национальный исследовательский медицинский университет имени Н.И.Пирогова» Министерства здравоохранения Российской Федерации, стажер-исследователь отдела внутренних болезней Медицинского научно-образовательного центра Федерального государственного бюджетного образовательного учреждения высшего образования «Московский государственный университет имени М.В.Ломоносова».</p><p>117997, Москва, ул. Островитянова, 1119991, Москва, Ленинские горы, 1</p><p>тел.: (499) 248-57-55</p></bio><bio xml:lang="en"><p>Layne Ya. Frantsuzevich, Assistant Lecturer, Department of Pulmonology, Pirogov Russian National Research Medical University (Pirogov Medical University), Ministry of Health of the Russian Federation, Intern Researcher, Department of Internal Medicine, Medical Research and Education Center, Federal State Budget Educational Institution of Higher Education M.V.Lomonosov Moscow State University.</p><p>Leninskie gory 1, Moscow, 119991ul. Ostrovityanova 1, Moscow, 117997</p><p>tel.: (499) 248-57-55</p></bio><email xlink:type="simple">frantsuzevitch@mail.ru</email><xref ref-type="aff" rid="aff-18"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0158-7056</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Черняев</surname><given-names>А. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Chernyaev</surname><given-names>A. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Черняев Андрей Львович – доктор медицинских наук,  профессор, профессор кафедры патологической анатомии и клинической патологической анатомии лечебного  факультета  РНИМУ им. Н.И. Пирогова МЗ РФ; заведующий отделом фундаментальной пульмонологии НИИ пульмонологии ФМБА России; ведущий научный  сотрудник  лаборатории клинической морфологии НИИ морфологии человека им. ак. А.П. Авцына РНЦ хирургии им. ак. Б.В. Петровского.</p><p>117997, Москва, ул. Островитянова, 1; 115682, Москва,  Ореховый бульвар, 28; 117418, Москва, ул. Цюрупы, 3</p><p>тел.: (495) 465-58-59</p></bio><bio xml:lang="en"><p>Andrey L. Chernyaev - Doctor of Medicine, Professor, Professor of the Department of Pathological Anatomy and Clinical Pathological Anatomy, Faculty of Medicine,  Pirogov Russian National  Research Medical University (Pirogov Medical University), Healthcare Ministry of Russia; Head of the Department of Fundamental Pulmonology, Federal Pulmonology Research Institute, Federal Medical and Biological Agency of Russia; Leading Researcher, Laboratory of Clinical Morphology, Avtsyn Research Institute оf Human Morphology оf Petrovsky National Research Centre оf Surgery.</p><p>Ostrovityanova ul. 1, Moscow, 117997; Orekhovyy bul’var 28,  Moscow, 115682; Tsyurupy ul. 3, Moscow, 117418</p><p>tel.: (495) 465-58-59</p></bio><email xlink:type="simple">cheral12@gmail.com</email><xref ref-type="aff" rid="aff-19"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1908-5601</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шмелев</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Shmelev</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шмелев Евгений Иванович – доктор медицинских наук, профессор, заведующий отделом дифференциальной диагностики туберкулеза  легких и экстракорпоральных методов лечения.</p><p>107564, Москва, Яузская аллея, 2</p><p>тел.: (499) 785-90-08</p></bio><bio xml:lang="en"><p>Evgeniy I. Shmelev - Doctor of Medicine,  Professor, Head of Differential Diagnosis of Pulmonary Tuberculosis and Extracorporeal Methods of Treatment Department, Federal State Scientific Institution “Central  Research Institute of Tuberculosis”.</p><p>Yauzskaya alleya 2, Moscow, 107564</p><p>tel.: (499) 785-90-08 </p></bio><email xlink:type="simple">eishmelev@mail.ru</email><xref ref-type="aff" rid="aff-13"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шмелева</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Shmeleva</surname><given-names>N. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шмелева Наталья Михайловна – кандидат медицинских наук, старший научный сотрудник отдела дифференциальной диагностики туберкулеза и экстракорпоральных методов лечения.</p><p>107564, Москва, Яузская аллея, 2</p><p>тел.: (499) 785-90-31</p></bio><bio xml:lang="en"><p>Natalia M. Shmeleva - Сandidate of Medicine, Senior Researcher, Differential Diagnosis of pulmonary  Tuberculosis  and Extracorporal Treatment Department, Federal State Scientific Institution “Central  Research Institute of Tuberculosis”.</p><p>Yauzskaya alleya 2, Moscow, 107564</p><p>tel.: (499) 785-90-31</p></bio><email xlink:type="simple">eishmelev@mail.ru</email><xref ref-type="aff" rid="aff-13"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет имени Н.И. Пирогова Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University (Pirogov Medical University), Healthcare Ministry of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Первый Московский  государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской  Федерации (Сеченовский Университет); Научно-исследовательский институт пульмонологии Федерального медико-биологического агентства России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov  First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov  University); Federal Pulmonology  Research  Institute,  Federal Medical  and Biological  Agency of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Academician I.P. Pavlov First St. Petersburg State Medical University of the Ministry of Healthcare of Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Московский городской научно-практический центр борьбы с туберкулезом Департамента здравоохранения города Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow  City Scientific and Practical Center for Combating Tuberculosis, Moscow City Department of Healthcare</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский Университет):</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov  First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>Казанский государственный медицинский университет Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kazan’ State Medical University, Healthcare Ministry of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-7"><aff xml:lang="ru"><institution>Главный военный клинический госпиталь имени академика Н.Н. Бурденко Министерства обороны Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Main Military Clinical Hospital named after academician N.N. Burdenko,  Ministry of Defense of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-8"><aff xml:lang="ru"><institution>Научно-исследовательский институт организации здравоохранения и медицинского менеджмента Департамента здравоохранения города Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific  Research Institute of Health Organization and Medical Management  of the Moscow City Department of Healthcare</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-9"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр фтизиопульмонологии и инфекционных заболеваний Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center for Phthisiopulmonology and Infectious Diseases, Ministry of Healthcare of Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-10"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-11"><aff xml:lang="ru"><institution>Московский государственный медико-стоматологический университет имени А.И. Евдокимова Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.I. Yevdokimov Moscow State University of Medicine and Dentistry of the Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-12"><aff xml:lang="ru"><institution>Омский государственный медицинский университет Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Omsk State Medical University, Healthcare Ministry of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-13"><aff xml:lang="ru"><institution>Центральный научно-исследовательский институт туберкулеза</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Central Research Institute of Tuberculosis</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-14"><aff xml:lang="ru"><institution>Научно-исследовательский институт пульмонологии Федерального медико-биологического агентства России; Московский  клинический научно-практический центр имени А.С. Логинова Департамента здравоохранения города Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Pulmonology Research Institute, Federal Medical and Biological Agency of Russia; State Budgetary Institution Moscow Clinical Scientific Center named after Loginov, Moscow City Department of Healthcare</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-15"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский&#13;
университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov  First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-16"><aff xml:lang="ru"><institution>Московский областной научно-исследовательский клинический институт имени М.Ф. Владимирского</institution><country>Россия</country></aff><aff xml:lang="en"><institution>M.F. Vladimirskiy State Moscow Regional Research Clinical Institute</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-17"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования «Российская медицинская академия непрерывного профессионального образования» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Federal Academy of Continued Medical Education, Healthcare Ministry of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-18"><aff xml:lang="ru"><institution>Федеральное государственное автономное образовательное учреждение высшего образования «Российский национальный исследовательский медицинский университет имени Н.И.Пирогова» Министерства здравоохранения Российской Федерации; Федеральное государственное бюджетное образовательное учреждение высшего образования «Московский государственный университет имени М.В.Ломоносова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University (Pirogov Medical University), Healthcare Ministry of Russia; Federal State Budget Educational Institution of Higher Education M.V.Lomonosov Moscow State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-19"><aff xml:lang="ru"><institution>Российский  национальный исследовательский медицинский университет имени Н.И. Пирогова Министерства здравоохранения Российской  Федерации; Научно-исследовательский институт пульмонологии Федерального медико-биологического агентства России; Научно-исследовательский  институт морфологии человека имени академика А.П. Авцына Российского научного центра хирургии имени академика Б.В. Петровского</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University (Pirogov Medical University), Healthcare Ministry of Russia; Federal Pulmonology  Research  Institute,  Federal Medical  and Biological  Agency of Russia; Avtsyn Research  Institute  of Human Morphology  of Federal State  Budgetary Scientific  Institution  “Petrovsky  National  Research  Centre of Surgery”</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>11</day><month>12</month><year>2022</year></pub-date><volume>32</volume><issue>6</issue><fpage>806</fpage><lpage>833</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чучалин А.Г., Авдеев С.Н., Айсанов З.Р., Баранова О.П., Борисов С.Е., Геппе Н.А., Визель А.А., Визель И.Ю., Зайцев А.А., Кравченко Н.Ю., Илькович М.М., Ловачева О.В., Малахов А.Б., Малявин A.Г., Петров Д.В., Романов В.В., Сивокозов И.В., Самсонова М.В., Соловьева И.П., Степанян И.Э., Терпигорев С.А., Тюрин И.Е., Французевич Л.Я., Черняев А.Л., Шмелев Е.И., Шмелева Н.М., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Чучалин А.Г., Авдеев С.Н., Айсанов З.Р., Баранова О.П., Борисов С.Е., Геппе Н.А., Визель А.А., Визель И.Ю., Зайцев А.А., Кравченко Н.Ю., Илькович М.М., Ловачева О.В., Малахов А.Б., Малявин A.Г., Петров Д.В., Романов В.В., Сивокозов И.В., Самсонова М.В., Соловьева И.П., Степанян И.Э., Терпигорев С.А., Тюрин И.Е., Французевич Л.Я., Черняев А.Л., Шмелев Е.И., Шмелева Н.М.</copyright-holder><copyright-holder xml:lang="en">Chuchalin A.G., Avdeev S.N., Aisanov Z.R., Baranova O.P., Borisov S.E., Geppe N.A., Vizel’ A.A., Vizel’ I.Y., Zaicev A.A., Kravchenko N.Y., Ilkovich M.M., Lovacheva O.V., Malakhov A.B., Malyavin A.G., Petrov D.V., Romanov V.V., Sivokozov I.V., Samsonova M.V., Solovieva I.P., Stepanyan I.E., Terpigorev S.A., Tyurin I.E., Frantsuzevich L.Y., Chernyaev A.L., Shmelev E.I., Shmeleva N.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.pulmonology.ru/pulm/article/view/4155">https://journal.pulmonology.ru/pulm/article/view/4155</self-uri><abstract><p>Саркоидоз является полиорганным гранулематозом неизвестной природы. При помощи  современных методов диагностики это заболевание возможно выявить на ранних стадиях. Для установления диагноза на основании сопоставления лучевых, клинических, морфологических и функциональных данных при отсутствии специфических маркеров требуется комплексный поход. Варианты течения саркоидоза без поражения органов дыхания представляют  значительные трудности. Во избежание  раннего  назначения гормонов  и цитостатических препаратов и, наоборот, в целях своевременного реагирования на прогрессирование и угрожающие состояния крайне актуально понимание времени  и средств  начала  лечения  саркоидоза.  Методы. Клинические рекомендации созданы  на основании анализа данных последних исследований саркоидоза, опубликованных на русском и английском языках. Каждый  тезис-рекомендация по проведению диагностических и лечебных мероприятий оценивается по шкалам оценки  уровня достоверности доказательств (1–5)  и убедительности  рекомендаций (по категориям  А, В, С). Клинические рекомендации содержат также комментарии и разъяснения к указанным тезисам-рекомендациям, алгоритмы  по диагностике, тактике терапии,  справочные материалы по использованию рекомендуемых препаратов. Целевой  аудиторией  данных  клинических рекомендаций являются  терапевты,  врачи  общей  практики,  пульмонологи, фтизиатры,  ревматологи,  дерматологи,   специалисты  лучевой  диагностики,  иммунологи, клинические  фармакологи.  Заключение. По данным представленных клинических рекомендаций освещаются современные сведения об эпидемиологии, клинических проявлениях,  диагностике и тактике  ведения  пациентов с саркоидозом. Одобрены  решением Научно-практического совета  Министерства здравоохранения Российской Федерации (2022).</p></abstract><trans-abstract xml:lang="en"><p>Sarcoidosis is a multi-organ granulomatosis  of unknown  origin. Modern  diagnostic methods  allow detecting  this disease at an early stage. The absence of specific markers requires a comprehensive  approach  to diagnosis based on comparison  of radiation,  clinical, morphological  and functional data. The course of sarcoidosis without damage to the respiratory system presents significant difficulties. It is extremely important  to understand the time and means of starting Sarcoidosis’s treatment to avoid the early initiation  of hormones  and cytostatics and, on the other hand,  to timely respond to progression and threatening  conditions.  Methods. Clinical recommendations are based on the analysis of Russian and English publications of the latest sarcoidosis research. The target audience of these clinical guidelines are therapists, general practitioners, pulmonologists, TB doctors, rheumatologists,  dermatologists,  radiation diagnosticians,  immunologists,  and clinical pharmacologists.  Each thesis-recommendation for diagnosis and treatment is evaluated on an 1 to 5 scale of levels of evidence and an A, B, C scale of the grades of recommendations. The clinical guidelines also contain comments and explanations for the theses-recommendations, diagnostic algorithms, treatment strategies, reference materials on the use of recommended drugs. Conclusion. Current information  on epidemiology, clinical manifestations,  diagnosis and management  strategies for patients with sarcoidosis are covered in the presented clinical guidelines. Approved by the decision of the Scientific and Practical Council of the Ministry of Health of the Russian Federation (2022).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>саркоидоз</kwd><kwd>диагностика</kwd><kwd>клинические проявления</kwd><kwd>лечение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>sarcoidosis</kwd><kwd>diagnosis</kwd><kwd>clinical manifestations</kwd><kwd>treatment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Визель А.А., ред. Саркоидоз. М.: Атмосфера; 2010.</mixed-citation><mixed-citation xml:lang="en">Vizel’ A.A, ed. [Sarcoidosis]. Moscow: Atmosphera; 2010 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">ATS/ERS/WASOG statement on sarcoidosis. Sarcoidosis statement committee. American Thoracic Society. European Respiratory Society. 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