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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pulmo</journal-id><journal-title-group><journal-title xml:lang="ru">Пульмонология</journal-title><trans-title-group xml:lang="en"><trans-title>PULMONOLOGIYA</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-0189</issn><issn pub-type="epub">2541-9617</issn><publisher><publisher-name>Scientific and Practical Journal “PULMONOLOGIYA” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18093/0869-0189-2023-33-1-92-101</article-id><article-id custom-type="elpub" pub-id-type="custom">pulmo-3957</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЗАМЕТКИ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PRACTICAL NOTES</subject></subj-group></article-categories><title-group><article-title>О патогенезе деструктивной пневмонии в период COVID-19: клиническое наблюдение</article-title><trans-title-group xml:lang="en"><trans-title>On the pathogenesis of destructive pneumonia during COVID-19: a clinical case</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3426-3426</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайцева</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaytseva</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зайцева Ольга Витальевна – доктор медицинских наук, профессор, заведующая кафедрой педиатрии.</p><p>127473, Москва, ул. Делегатская, 20, стр. 1; тел.: (499) 268-84-46</p></bio><bio xml:lang="en"><p>Ul. Delegatskaya 20/1, Moscow, 127473; ul. Rubtsovsko-Dvortsovaya 1/3, Moscow, 107014</p></bio><email xlink:type="simple">olga6505963@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8340-3064</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Толстова</surname><given-names>Е. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Tolstova</surname><given-names>E. М.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Толстова Евгения Михайловна – кандидат медицинских наук, доцент кафедры педиатрии.</p><p>127473, Москва, ул. Делегатская, 20, стр. 1; тел.: (926) 810-63-59</p></bio><bio xml:lang="en"><p>Ul. Delegatskaya 20/1, Moscow, 127473; ul. Rubtsovsko-Dvortsovaya 1/3, Moscow, 107014</p></bio><email xlink:type="simple">tepec@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6808-7670</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хаспеков</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Khaspekov</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хаспеков Дмитрий Викторович – кандидат медицинских наук, заведующий отделением торакальный хирургии.</p><p>107014, Москва, ул. Рубцовско-Дворцовая, 1 / 3; тел.: (495) 530-12-79</p></bio><bio xml:lang="en"><p>Ul. Rubtsovsko-Dvortsovaya 1/3, Moscow, 107014</p></bio><email xlink:type="simple">khaspekov@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4240-0072</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ткаченко</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tkachenko</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ткаченко Надежда Витальевна – врач-педиатр отделения торакальной хирургии.</p><p>107014, Москва, ул. Рубцовско-Дворцовая, 1 / 3; тел.: (495) 530-12-79</p></bio><bio xml:lang="en"><p>Ul. Rubtsovsko-Dvortsovaya 1/3, Moscow, 107014</p></bio><email xlink:type="simple">nadinnn777@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0412-4938</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шолохова</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Scholohova</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шолохова Наталия Александровна – кандидат медицинских наук, доцент кафедры лучевой диагностики МГМСУ имени А.И.Евдокимова; заведующая отделением лучевой диагностики Детская ГКБ святого Владимира Департамента здравоохранения города Москвы</p><p>127473, Москва, ул. Делегатская, 20, стр. 1; 107014, Москва, ул. Рубцовско-Дворцовая, 1 / 3; тел.: (495) 530-12-79</p></bio><bio xml:lang="en"><p>Ul. Delegatskaya 20/1, Moscow, 127473; ul. Rubtsovsko-Dvortsovaya 1/3, Moscow, 107014</p></bio><email xlink:type="simple">sholohova@bk.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6636-3371</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Симоновская</surname><given-names>Х. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Simonovskaya</surname><given-names>H. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Симоновская Хильда Юрьевна – ассистент кафедры педиатрии.</p><p>127473, Москва, ул. Делегатская, 20, стр. 1; тел.: (499) 268-84-46</p></bio><bio xml:lang="en"><p>Ul. Delegatskaya 20/1, Moscow, 127473</p></bio><email xlink:type="simple">hildas@yandex.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5277-9808</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Беляева</surname><given-names>Т. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Belyaeva</surname><given-names>Т. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Беляева Татьяна Юрьевна – заместитель главного врача по лечебной работе.</p><p>127473, Москва, ул. Делегатская, 20, стр. 1; тел.: (495) 530-12-79</p></bio><bio xml:lang="en"><p>Ul. Rubtsovsko-Dvortsovaya 1/3, Moscow, 107014</p></bio><email xlink:type="simple">dgkbsv@zdrav.mos.ru</email><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования Московский государственный медико-стоматологический университет имени А.И. Евдокимова, Министерство здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of the Higher Education A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Государственное бюджетное учреждение здравоохранения города Москвы Детская городская клиническая больница святого Владимира, Департамент здравоохранения города Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of the Higher Education A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования Московский государственный медико-стоматологический университет имени А.И.Евдокимова, Министерство здравоохранения Российской Федерации; Государственное бюджетное учреждение здравоохранения города Москвы Детская городская клиническая больница святого Владимира, Департамент здравоохранения города Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of the Higher Education A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Ministry of Healthcare of the Russian Federation; Federal State Budgetary Educational Institution of the Higher Education A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования Московский государственный медико-стоматологический университет имени А.И.Евдокимова, Министерство здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of the Higher Education A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования Московский государственный медико-стоматологический университет имени А.И.Евдокимова, Министерство здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Budgetary Healthcare Institution Children’s City Clinical Hospital of St. Vladimir Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>11</day><month>02</month><year>2023</year></pub-date><volume>33</volume><issue>1</issue><fpage>92</fpage><lpage>101</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зайцева О.В., Толстова Е.М., Хаспеков Д.В., Ткаченко Н.В., Шолохова Н.А., Симоновская Х.Ю., Беляева Т.Ю., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Зайцева О.В., Толстова Е.М., Хаспеков Д.В., Ткаченко Н.В., Шолохова Н.А., Симоновская Х.Ю., Беляева Т.Ю.</copyright-holder><copyright-holder xml:lang="en">Zaytseva O.V., Tolstova E.М., Khaspekov D.V., Tkachenko N.V., Scholohova N.A., Simonovskaya H.Y., Belyaeva Т.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.pulmonology.ru/pulm/article/view/3957">https://journal.pulmonology.ru/pulm/article/view/3957</self-uri><abstract><p>Актуальность проблемы внебольничных пневмоний в педиатрии объясняется высоким уровнем заболеваемости, риском тяжелого течения и неблагоприятного исхода. В последние годы отмечается увеличение частоты деструктивных форм заболевания.</p><p>Целью работы явился анализ клинического случая течения деструктивной пневмонии (ДП) у ребенка 1 года 2 мес., госпитализированного в Государственное бюджетное учреждение здравоохранения города Москвы «Детская городская клиническая больница святого Владимира Департамента здравоохранения города Москвы» (2021), с точки зрения современных данных о патогенезе заболевания.</p><p>Заключение. В условиях пандемии COVID-19 (COronaVIrus Disease 2019) пульмонологи и детские хирурги столкнулись с нестандартным течением ДП. В последнее время представления о роли системы коагуляции расширились благодаря увеличению числа исследований патофизиологических процессов при вирусных интерстициальных пневмониях, однако появились новые вопросы, касающиеся клинического течения и развития патологического инфекционного процесса.</p></abstract><trans-abstract xml:lang="en"><p>Community-acquired pneumonia is a potentially serious infection in children with high morbidity rate, risk of severe course and unfavorable outcomes. Specialists have noted the increased incidence of the destructive forms in the recent years.</p><sec><title>Aim</title><p>Aim. To present a clinical case of destructive pneumonia in a 1 year 2 month old child, hospitalized in the State Budgetary Healthcare Institution “Children’s City Clinical Hospital of St. Vladimir Moscow Healthcare Department”, and analyze it in terms of current understanding on the disease pathogenesis.</p></sec><sec><title>Conclusion</title><p>Conclusion. During COVID-19 (COronaVIrus Disease 2019) pandemic, pulmonologists and pediatric surgeons encountered an unconventional course of destructive pneumonia. A large number of studies of pathophysiological processes in acute viral interstitial pneumonias have recently allowed to expand our understanding of the role of coagulation system. At the same time, new questions arose concerning the clinical course and development of the pathological infectious process.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>деструктивная пневмония</kwd><kwd>система гемостаза</kwd><kwd>COVID-19 у детей</kwd><kwd>некротизирующая пневмония</kwd><kwd>коагуляция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>destructive pneumonia</kwd><kwd>hemostasis</kwd><kwd>COVID-19 in children</kwd><kwd>necrotizing pneumonia</kwd><kwd>coagulation</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Спонсорская поддержка исследования отсутствовала</funding-statement><funding-statement xml:lang="en">The study was not sponsored</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Yun K.W., Wallihan R., Juergensen A., Ramilo O. Community-acquired pneumonia in children: myths and facts. Am. J. 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