pulmoПульмонологияPULMONOLOGIYA0869-01892541-9617Scientific and Practical Journal “PULMONOLOGIYA” LLC10.18093/0869-0189-2022-32-2-244-252pulmo-3862Research ArticleОБЗОРЫREVIEWСиндром старческой астении у пациентов с заболеваниями респираторной системыFrailty syndrome in patients with respiratory diseaseshttps://orcid.org/0000-0002-3023-6239БаздыревЕ. Д.BazdyrevE. D.

Баздырев Евгений Дмитриевич – доктор медицинских наук, заведующий лабораторией эпидемиологии сердечно-сосудистых заболеваний 

650002, Россия, Кемерово, Сосновый бул., 6

Evgeny D. Bazdyrev, Doctor of Medicine, Head of the Laboratory of Epidemiology of Cardiovascular Diseases

Sosnoviy bul. 6, Kemerovo, 650002, Russia

edb624@mail.ruhttps://orcid.org/0000-0001-6867-5694ГофманЛ. С.GofmanL. S.

Гофман Людмила Сергеевна, врач-пульмонолог 

650066, Россия, Кемерово, Октябрьский просп., 22

Liudmila S. Gofman, Pulmonologist

Oktyabrskiy prosp. 22, Kemerovo, 650066, Russia

shelly.shell538@gmail.comhttps://orcid.org/0000-0002-4642-3610БарбарашО. Л.BarbarashO. L.

Барбараш Ольга Леонидовна – доктор медицинских наук, профессор, член-корр. Российской академии наук, директор Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний

650002, Россия, Кемерово, Сосновый бул., 6

Olga L. Barbarash, Doctor of Medicine, Professor, Corresponding Member of Russian Academy of Sciences, Director Research Institute for Complex Issues of Cardiovascular Diseases

Sosnoviy bul. 6, Kemerovo, 650002, Russia

 

olb61@mail.ruФедеральное государственное бюджетное научное учреждение «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний»РоссияFederal State Budgetary Scientific Institution “Research Institute for Complex Issues of Cardiovascular DiseasesRussian FederationГосударственное автономное учреждение здравоохранения «Кузбасская областная клиническая больница имени С.В.Беляева» Министерства здравоохранения КузбассаРоссияState Autonomous Health Institution “S.V.Belyaev Kuzbass Regional Clinical Hospital”, Healthcare Ministry of KuzbassRussian Federation202202052022322244252Copyright © Баздырев Е.Д., Гофман Л.С., Барбараш О.Л., 20222022Баздырев Е.Д., Гофман Л.С., Барбараш О.Л.Bazdyrev E.D., Gofman L.S., Barbarash O.L.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.pulmonology.ru/pulm/article/view/3862

По мере старения населения заболевания легких, такие как бронхиальная астма, хроническая обструктивная болезнь легких – одни из наиболее распространенных у пожилых людей, представляют собой важную проблему для системы здравоохранения. Синдром старческой астении (ССА) – гериатрический синдром, который характеризуется возраст-ассоциированным снижением физиологического резерва и функций многих систем, в т. ч. респираторной, приводит к повышенной уязвимости организма пожилого человека.

Целью работы явился обзор исследований, при проведении которых затрагивались вопросы современного представления о ССА, патофизиологических изменений респираторной систему у пожилых, распространенности, а также возможных механизмах развития ССА у пожилых пациентов с заболеваниями респираторной системы.

Заключение. ССА и заболевания респираторной системы тесно связаны между собой. С одной стороны, эти патофизиологические процессы закономерно присутствуют у пожилых людей, с другой – это сама патология, которая вносит дополнительные изменения, усиливающих процесс старения. Несомненно, изучение вопроса взаимодействия, а также влияния ССА на течение и исходы заболевания имеет огромное значение для улучшения прогноза у пожилых пациентов. Раннее распознавание ССА у пациентов с патологией респираторной системы поможет предотвратить или отсрочить ухудшение функциональности, инвалидности и смерти. При оценке степени «слабости» у пациентов могут улучшиться стратификация рисков и персонифицированный подход к управлению данными рисками, а также результаты лечения.

Respiratory diseases such as asthma and chronic obstructive pulmonary disease are especially prevalent in elderly people and have become a significant problem for healthcare due to ageing of population. Frailty syndrome (FS) is a geriatric syndrome characterized by an age-associated declines in physiologic reserve and functions of multiple systems, including respiratory system. This syndrome leads to increased vulnerability of the elderly.

The aim of the study is to review the available data on modern understanding of FS, pathophysiological changes in the respiratory system associated with aging, the prevalence of FS, and its potential underlying mechanisms in elderly patients with respiratory diseases.

Conclusion. FS is strongly associated with respiratory diseases. On one hand, these pathophysiological processes are inherent in elderly patients. On the other hand, the condition itself causes additional changes that enhance the aging process. Undoubtedly, their association and the influence of FS on the course and outcomes of the respiratory disease should be studied to improve the prognosis of elderly patients. Early recognition of FS in patients with respiratory diseases will help prevent or delay decline in physiologic reserve and functions of multiple systems and lower the disability and mortality rates. Comprehensive assessment of “frail” patients can assist in developing a better risk stratification and provide a personalized approach to managing these risks, as well as improve the patient outcomes.

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The authors declare that there are no conflicts of interest present.