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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pulmo</journal-id><journal-title-group><journal-title xml:lang="ru">Пульмонология</journal-title><trans-title-group xml:lang="en"><trans-title>PULMONOLOGIYA</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-0189</issn><issn pub-type="epub">2541-9617</issn><publisher><publisher-name>Scientific and Practical Journal “PULMONOLOGIYA” LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pulmo-3644</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Специфическая иммунотерапия бронхиальной астмы</article-title><trans-title-group xml:lang="en"><trans-title>Specific immune therapy of bronchial asthma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нугманова</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Nugmanova</surname><given-names>D. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>НИИ пульмонологии МЗ России</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>1994</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>1994</year></pub-date><volume>0</volume><issue>4</issue><fpage>77</fpage><lpage>81</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Нугманова Д.С., 1994</copyright-statement><copyright-year>1994</copyright-year><copyright-holder xml:lang="ru">Нугманова Д.С.</copyright-holder><copyright-holder xml:lang="en">Nugmanova D.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.pulmonology.ru/pulm/article/view/3644">https://journal.pulmonology.ru/pulm/article/view/3644</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Адо А.Д., Червинская Т.А., Вылегжанина Т.Г., КасперовичЛ.Л. Гиперреактивность бронхов и специфическая иммунотерапия при пылевой и клещевой бронхиальной астме / / Всесоюзный конгресс по болезням органовдыхания, 2-й: Тезисы докладов.— Челябинск, 1991.— С.52; No 19.</mixed-citation><mixed-citation xml:lang="en">Адо А.Д., Червинская Т.А., Вылегжанина Т.Г., КасперовичЛ.Л. Гиперреактивность бронхов и специфическая иммунотерапия при пылевой и клещевой бронхиальной астме / / Всесоюзный конгресс по болезням органовдыхания, 2-й: Тезисы докладов.— Челябинск, 1991.— С.52; No 19.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Аллергические болезни у детей / Студеникин М.Я., Соколова Т.С., Ботвиньева Б.В. и др.— М.: Медицина, 1986.</mixed-citation><mixed-citation xml:lang="en">Аллергические болезни у детей / Студеникин М.Я., Соколова Т.С., Ботвиньева Б.В. и др.— М.: Медицина, 1986.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Горячкина Л .А., Поспелова Р.А., Храмцова Н.Н., Фролова М.К. Особенности специфической гипосенсибилизирующей терапии больных поллинозом / / Препараты и методы для лечения и диагностики аллергии.— М., 1985.— С.35—36.</mixed-citation><mixed-citation xml:lang="en">Горячкина Л .А., Поспелова Р.А., Храмцова Н.Н., Фролова М.К. Особенности специфической гипосенсибилизирующей терапии больных поллинозом / / Препараты и методы для лечения и диагностики аллергии.— М., 1985.— С.35—36.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Порошина ЮЛ., Полсачева О.В., Титова С.М., Шустова В.И. Клинико-иммунологическое изучение различных методов специфической иммунотерапии при поллинозах / / Иммунология.— 1985.— No 5.— С.50—54.</mixed-citation><mixed-citation xml:lang="en">Порошина ЮЛ., Полсачева О.В., Титова С.М., Шустова В.И. Клинико-иммунологическое изучение различных методов специфической иммунотерапии при поллинозах / / Иммунология.— 1985.— No 5.— С.50—54.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Фрадкин В.А. Диагностические и лечебные аллергены.— М.: М едицина, 1990.</mixed-citation><mixed-citation xml:lang="en">Фрадкин В.А. Диагностические и лечебные аллергены.— М.: М едицина, 1990.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Чучалин А.Г. Актуальные вопросы пульмонологии / / Пульмонология.— 1992.— No 3.— С.6—9.</mixed-citation><mixed-citation xml:lang="en">Чучалин А.Г. Актуальные вопросы пульмонологии / / Пульмонология.— 1992.— No 3.— С.6—9.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Aalberse R.C., Van der Gaag R., Leeuwen J. Serologic aspects of IgG4 antibodies. I. Prolonged immunization rezults in an IgG4 restricted response / / J. Im m unol.— 1983.— Vol.130.— P .722—725.</mixed-citation><mixed-citation xml:lang="en">Aalberse R.C., Van der Gaag R., Leeuwen J. Serologic aspects of IgG4 antibodies. I. Prolonged immunization rezults in an IgG4 restricted response / / J. Im m unol.— 1983.— Vol.130.— P .722—725.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Adkinson N.F. What we know and what we need to know about immunotherapy for allergic asthma / / Immunotherapy / Ed. U.G.Svendsen, H.J.Malling.— Kobenhavn, 1989.— P.93—105.</mixed-citation><mixed-citation xml:lang="en">Adkinson N.F. What we know and what we need to know about immunotherapy for allergic asthma / / Immunotherapy / Ed. U.G.Svendsen, H.J.Malling.— Kobenhavn, 1989.— P.93—105.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Bentley AM., Meng Q., Robinson D.S. et al. Increases in activated T Lymphocytes, eosinophils, and cytokine mRNA expression for interleukin-5 and granulocyte/m acrophage colony-stimulating factor in bronchial biopsies after allergen inhalation challenge in atopic asthmatics / / Am. J. Respir. Cell. Mol. Biol.— 1993.— Vol.8.— P.35—42.</mixed-citation><mixed-citation xml:lang="en">Bentley AM., Meng Q., Robinson D.S. et al. Increases in activated T Lymphocytes, eosinophils, and cytokine mRNA expression for interleukin-5 and granulocyte/m acrophage colony-stimulating factor in bronchial biopsies after allergen inhalation challenge in atopic asthmatics / / Am. J. Respir. Cell. Mol. Biol.— 1993.— Vol.8.— P.35—42.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Berzovsky J.A., Berkower I.J. Immunogenicity and antigen structure / / Fundamentals of Immunology / Ed. W .E.Paul. 2-nd Ed.— New York: Raven Press, 1989.— P. 169—208.</mixed-citation><mixed-citation xml:lang="en">Berzovsky J.A., Berkower I.J. Immunogenicity and antigen structure / / Fundamentals of Immunology / Ed. W .E.Paul. 2-nd Ed.— New York: Raven Press, 1989.— P. 169—208.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Bousquet J., Hejjaoui A., Clauzel A.-M., Guerin B., Dhiuert H.t Skassa-Brociek W., Michel F.-B. Specific immunotherapy with a stundardized Dermatophagoides pteronissinus extract. II. Prediction of efficacy of immunotherapy / / J. Allergy Clin. Immunol.— 1988.— Vol.82.— P .971—977.</mixed-citation><mixed-citation xml:lang="en">Bousquet J., Hejjaoui A., Clauzel A.-M., Guerin B., Dhiuert H.t Skassa-Brociek W., Michel F.-B. Specific immunotherapy with a stundardized Dermatophagoides pteronissinus extract. II. Prediction of efficacy of immunotherapy / / J. Allergy Clin. Immunol.— 1988.— Vol.82.— P .971—977.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Bousquet J., Michel F.-B. Specific immunotherapy in asthma / / ACI News.— 1992.— Vol.4, No 4.— P. 106—109.</mixed-citation><mixed-citation xml:lang="en">Bousquet J., Michel F.-B. Specific immunotherapy in asthma / / ACI News.— 1992.— Vol.4, No 4.— P. 106—109.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Bucur J., Dreborg S., Einarsson R., Ljungstedt-Pahlman I., Nilsson J.-E., Persson G. Immunotherapy with dog-sensitive and cat-sensitive asthmatics / / Ann. Allergy.— 1989.— Vol.62.— P .355—361.</mixed-citation><mixed-citation xml:lang="en">Bucur J., Dreborg S., Einarsson R., Ljungstedt-Pahlman I., Nilsson J.-E., Persson G. Immunotherapy with dog-sensitive and cat-sensitive asthmatics / / Ann. Allergy.— 1989.— Vol.62.— P .355—361.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Canonica G.W., Mingary M.C., Melioli G., Colombatti M., Moretta L. Imbalances of T cell subpopulations in patients with atopic diseases and effect of specific immunotherapy / / J. Immunol.— 1979.— Vol.125, No 6.— P.2669—2673.</mixed-citation><mixed-citation xml:lang="en">Canonica G.W., Mingary M.C., Melioli G., Colombatti M., Moretta L. Imbalances of T cell subpopulations in patients with atopic diseases and effect of specific immunotherapy / / J. Immunol.— 1979.— Vol.125, No 6.— P.2669—2673.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Chapman M.D. Use of nonstimulatory peptides: A new strategy for immunotherapy? / / J. Allergy Clin. Immunol.— 1991.— Vol.88, No 3, Pt 1.— P.300—302.</mixed-citation><mixed-citation xml:lang="en">Chapman M.D. Use of nonstimulatory peptides: A new strategy for immunotherapy? / / J. Allergy Clin. Immunol.— 1991.— Vol.88, No 3, Pt 1.— P.300—302.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Corrigan C.J., Kay A.B. T-cells and eosinophils in the pathogenesis of asthma / / Immunol. Today.— 1992.— Vol.13, No 12.— P .501—507.</mixed-citation><mixed-citation xml:lang="en">Corrigan C.J., Kay A.B. T-cells and eosinophils in the pathogenesis of asthma / / Immunol. Today.— 1992.— Vol.13, No 12.— P .501—507.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Creticos P.S., Van Metre T.E.Jr., Mardiney M.R., Rosenberg G.L., Norman P.C., Adkinson N.F.Jr. Dose response of IgE and IgG antibodies during ragweed immunotherapy / / J. Allergy Clin. Immunol.— 1984.— Vol.73.— P.94—104.</mixed-citation><mixed-citation xml:lang="en">Creticos P.S., Van Metre T.E.Jr., Mardiney M.R., Rosenberg G.L., Norman P.C., Adkinson N.F.Jr. Dose response of IgE and IgG antibodies during ragweed immunotherapy / / J. Allergy Clin. Immunol.— 1984.— Vol.73.— P.94—104.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Creticos P.S. Immunotherapy - modulation of inflammation and mediators / / Immunotherapy / Eds U.G.Svendsen, H.J.Malling.— Kobenhavn, 1989.— P .69—76.</mixed-citation><mixed-citation xml:lang="en">Creticos P.S. Immunotherapy - modulation of inflammation and mediators / / Immunotherapy / Eds U.G.Svendsen, H.J.Malling.— Kobenhavn, 1989.— P .69—76.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Debelic M. Factors involved in the selection of patients for immunotherapy / / Selection of Allergic Patients for Immunotherapy. Proceeding 2-nd BRL Kurhaus Workshop on Allergy.— Scheven- ingen, 1988.— P .25—36.</mixed-citation><mixed-citation xml:lang="en">Debelic M. Factors involved in the selection of patients for immunotherapy / / Selection of Allergic Patients for Immunotherapy. Proceeding 2-nd BRL Kurhaus Workshop on Allergy.— Scheven- ingen, 1988.— P .25—36.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Dreborg S., Agrell B., Foucard T., Kjellman N.I., Koivikko A., Nilsson S. A double-blind, multicenter immunotherapy trail in children, using a purified and standardized Cladosporium herbarum preparation. I. Clinical results / / Allergy.— 1988.— Vol.41, No 2.— P.131—140.</mixed-citation><mixed-citation xml:lang="en">Dreborg S., Agrell B., Foucard T., Kjellman N.I., Koivikko A., Nilsson S. A double-blind, multicenter immunotherapy trail in children, using a purified and standardized Cladosporium herbarum preparation. I. Clinical results / / Allergy.— 1988.— Vol.41, No 2.— P.131—140.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Dreborg S., Akerblom E.B. Immunotherapy with monomethoxy- polyethylene glycol modified allergens / / Crit. Rev. Ther. Drug. Carrier. Syst.— 1990.— Vol.6, No 4.— P.315—365.</mixed-citation><mixed-citation xml:lang="en">Dreborg S., Akerblom E.B. Immunotherapy with monomethoxy- polyethylene glycol modified allergens / / Crit. Rev. Ther. Drug. Carrier. Syst.— 1990.— Vol.6, No 4.— P.315—365.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">D’Souza M.F., Pepys J., Wells I.D., Tai E., Palmer F., Overell B.G., McGrath I.T., Megson M. Hyposensitization with Dermatophagoides pteronissinus in house dust allergy: a controlled study of clinical and immunological effects / / Clin. Allergy.— 1973.— Vol.3.— P .177—193.</mixed-citation><mixed-citation xml:lang="en">D’Souza M.F., Pepys J., Wells I.D., Tai E., Palmer F., Overell B.G., McGrath I.T., Megson M. Hyposensitization with Dermatophagoides pteronissinus in house dust allergy: a controlled study of clinical and immunological effects / / Clin. Allergy.— 1973.— Vol.3.— P .177—193.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Durham S.R., Varney V., Gaga M., Frew A.J., Jacobson M., Kay A.B. Immunotherapy and allergic inflammation / / Clin. Exp. Allergy.— 1991.— Vol.21, No 1.— P.206—210.</mixed-citation><mixed-citation xml:lang="en">Durham S.R., Varney V., Gaga M., Frew A.J., Jacobson M., Kay A.B. Immunotherapy and allergic inflammation / / Clin. Exp. Allergy.— 1991.— Vol.21, No 1.— P.206—210.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Ebner H., Neuchrest C., Havelec L., Kraft D. Comparative studies of the effectiveness of specific immunotherapy in housdust mite allergy / / W ien. Klin. W ochenschr.— 1989.— Bd 101, No 15.— S.504—511.</mixed-citation><mixed-citation xml:lang="en">Ebner H., Neuchrest C., Havelec L., Kraft D. Comparative studies of the effectiveness of specific immunotherapy in housdust mite allergy / / W ien. Klin. W ochenschr.— 1989.— Bd 101, No 15.— S.504—511.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Furin M.J., Norman P., Creticos P., Proud D., Kagey-Sobotka A., Lichtenstein L.M., Nuclerio R. Immunotherapy decreases antigen-induced eosinophil cell migration into the nasal cavity / / J. Allergy Clin. Immunol.— 1991.— Vol.88, No 1.— P.27—32.</mixed-citation><mixed-citation xml:lang="en">Furin M.J., Norman P., Creticos P., Proud D., Kagey-Sobotka A., Lichtenstein L.M., Nuclerio R. Immunotherapy decreases antigen-induced eosinophil cell migration into the nasal cavity / / J. Allergy Clin. Immunol.— 1991.— Vol.88, No 1.— P.27—32.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Galant S.P. Allergy shots for hay fever / / Postgrad. Med.— 1989.— Vol.85, No 6.— P.203—209.</mixed-citation><mixed-citation xml:lang="en">Galant S.P. Allergy shots for hay fever / / Postgrad. Med.— 1989.— Vol.85, No 6.— P.203—209.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Gurka G.P., Rocklin R. Immunologic responses during allergen- specific immunotherapy for respiratory allergy / / Ann. Allergy.— 1988.— Vol.61, No 10.— P.239—243.</mixed-citation><mixed-citation xml:lang="en">Gurka G.P., Rocklin R. Immunologic responses during allergen- specific immunotherapy for respiratory allergy / / Ann. Allergy.— 1988.— Vol.61, No 10.— P.239—243.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Gurka G.P., Ohman J.L., Rosenwasser L.J. Allergen-specific human T cell clones: derivation, specificity, and activation requirements J / J. Allergy Clin. Immunol.— 1989.— Vol.83.— P.945— 954.</mixed-citation><mixed-citation xml:lang="en">Gurka G.P., Ohman J.L., Rosenwasser L.J. Allergen-specific human T cell clones: derivation, specificity, and activation requirements J / J. Allergy Clin. Immunol.— 1989.— Vol.83.— P.945— 954.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Haugaard L., Norregaard O.F., Dahl R. In-hospital sting challenge in insect venom-allergic patients after stopping venom immunotherapy [see comments] / / Ibid.— 1991.— Vol.87, No 3.— P.699—702.</mixed-citation><mixed-citation xml:lang="en">Haugaard L., Norregaard O.F., Dahl R. In-hospital sting challenge in insect venom-allergic patients after stopping venom immunotherapy [see comments] / / Ibid.— 1991.— Vol.87, No 3.— P.699—702.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Hedlin G., Graff-Lonneuig V:, Heilborn H., Lilja G., Norrlind K., Pegelow K.O., Sundín B., Lowenstein H. Immunotherapy with cat and dog-dander extracts in Children and adults with asthma / / Immunotherapy / Eds. U. G. Svendsen, H.J.Malling.-Kobenhavn, 1989.— P .4 9—60.</mixed-citation><mixed-citation xml:lang="en">Hedlin G., Graff-Lonneuig V:, Heilborn H., Lilja G., Norrlind K., Pegelow K.O., Sundín B., Lowenstein H. Immunotherapy with cat and dog-dander extracts in Children and adults with asthma / / Immunotherapy / Eds. U. G. Svendsen, H.J.Malling.-Kobenhavn, 1989.— P .4 9—60.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Hedlin G. Treatment with cat allergy vaccines / / Clin. Exp. Allergy.— 1991.— Vol.21, Suppl.l.— P.211—215.</mixed-citation><mixed-citation xml:lang="en">Hedlin G. Treatment with cat allergy vaccines / / Clin. Exp. Allergy.— 1991.— Vol.21, Suppl.l.— P.211—215.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Heusser C.H. Modifying activity of memory B cells. Avoiding the risks of SIT / / FISONS Conference Reporter at EAACI.— Paris, 1992.— P.2—3.</mixed-citation><mixed-citation xml:lang="en">Heusser C.H. Modifying activity of memory B cells. Avoiding the risks of SIT / / FISONS Conference Reporter at EAACI.— Paris, 1992.— P.2—3.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Horst M., Hejjaoui A., Horst V., Michel F.B., Bousquet J. Doubleblind, placebo-controlled rush immunotherapy with a stan- dartized Alternaria extract / / J. Allergy Clin. Immunol.— 1990.— Vol.85.— P.460—472.</mixed-citation><mixed-citation xml:lang="en">Horst M., Hejjaoui A., Horst V., Michel F.B., Bousquet J. Doubleblind, placebo-controlled rush immunotherapy with a stan- dartized Alternaria extract / / J. Allergy Clin. Immunol.— 1990.— Vol.85.— P.460—472.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Hsieh K.H. Decreased expression of high affinity interleukin 2 receptor after hyposensitization to house dust / / Ann. Allergy.— 1987.— Vol.59, No 1.— P.57—62.</mixed-citation><mixed-citation xml:lang="en">Hsieh K.H. Decreased expression of high affinity interleukin 2 receptor after hyposensitization to house dust / / Ann. Allergy.— 1987.— Vol.59, No 1.— P.57—62.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Iliopoulos O., Proud D.P., Adkinson N.F., Creticos P.S., Norman P.S., Kagey-Sobotka A., Lichtenstein L.M., Naclerio R.M. Effects of immunotherapy in early, late, and rechallenge nasal reaction to provocation with allergen: changes in inflammatory mediators and cells / / J.Allergy Clin. Immunol.— 1991.— Vol.87, No 4.— P .855—866.</mixed-citation><mixed-citation xml:lang="en">Iliopoulos O., Proud D.P., Adkinson N.F., Creticos P.S., Norman P.S., Kagey-Sobotka A., Lichtenstein L.M., Naclerio R.M. Effects of immunotherapy in early, late, and rechallenge nasal reaction to provocation with allergen: changes in inflammatory mediators and cells / / J.Allergy Clin. Immunol.— 1991.— Vol.87, No 4.— P .855—866.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Ishizaka K., Joh K., Shibata.R., Wagatsuma Y., Nakanishi M., Tomizawa K., Kojima K., Kandil E., Sakiyama Y'., Matsumoto S. Regulation of IgE and IgG4 synthesis in patients with hyper IgE syndrome / / Immunology.— 1990.— Vol.70, No 3.— P.414—416.</mixed-citation><mixed-citation xml:lang="en">Ishizaka K., Joh K., Shibata.R., Wagatsuma Y., Nakanishi M., Tomizawa K., Kojima K., Kandil E., Sakiyama Y'., Matsumoto S. Regulation of IgE and IgG4 synthesis in patients with hyper IgE syndrome / / Immunology.— 1990.— Vol.70, No 3.— P.414—416.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Jarolim E., Poulsen L.K., Stadler B.M., Ritter C., Kraemer R., de Week A. A long-term follow-up study of hyposensitization with im m unoblotting / / J. A llergy Clin. Im m unol.— 1990.— Vol.85.— P.996—1004.</mixed-citation><mixed-citation xml:lang="en">Jarolim E., Poulsen L.K., Stadler B.M., Ritter C., Kraemer R., de Week A. A long-term follow-up study of hyposensitization with im m unoblotting / / J. A llergy Clin. Im m unol.— 1990.— Vol.85.— P.996—1004.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Johnstone D.E. Study of the role of antigen dosage in the treatm ent of poollinosis and pollen asthm a J / J. Dis. Child.— 1957.— Vol.94.— P.1—5.</mixed-citation><mixed-citation xml:lang="en">Johnstone D.E. Study of the role of antigen dosage in the treatm ent of poollinosis and pollen asthm a J / J. Dis. Child.— 1957.— Vol.94.— P.1—5.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Kang Bann C., Jonson J., Morgan C., Chang J.L. The role of immunotherapy in cockroach asthma / / J. Asthma.— 1988.— Vol.25, No. 4.— P.205—218.</mixed-citation><mixed-citation xml:lang="en">Kang Bann C., Jonson J., Morgan C., Chang J.L. The role of immunotherapy in cockroach asthma / / J. Asthma.— 1988.— Vol.25, No. 4.— P.205—218.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Kemeny DM., Tomioka H., Tsutsumi A., Koike T., Lessof M.H., Lee T.H. The relationship between anti-IgE auto-antibodies and the IgE response to wasp venom during immunotherapy / / Clin. Exp. Allergy.— 1990.— Vol.20.— P.67—69.</mixed-citation><mixed-citation xml:lang="en">Kemeny DM., Tomioka H., Tsutsumi A., Koike T., Lessof M.H., Lee T.H. The relationship between anti-IgE auto-antibodies and the IgE response to wasp venom during immunotherapy / / Clin. Exp. Allergy.— 1990.— Vol.20.— P.67—69.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Kemeny D.M., Diaz-Sanchez D., Holmes B.J. CD8+ T cells in allergy / / Allergy.— 1992.— Vol.47, No 1.— P.12—21.</mixed-citation><mixed-citation xml:lang="en">Kemeny D.M., Diaz-Sanchez D., Holmes B.J. CD8+ T cells in allergy / / Allergy.— 1992.— Vol.47, No 1.— P.12—21.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Kips J.S., Joos G.F., Peleman R.A., Pauwels K.A. Cytokines in asthma — the latest results / / ACI News.— 1992.— Vol.4, No 4.— P.110—112.</mixed-citation><mixed-citation xml:lang="en">Kips J.S., Joos G.F., Peleman R.A., Pauwels K.A. Cytokines in asthma — the latest results / / ACI News.— 1992.— Vol.4, No 4.— P.110—112.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Le Roux P., Le Luyer B. Accelerated desensitization to Dermatophagoides pteronissinus mites in children with asthma. Results of two years of immunotherapy / / Allerg. Immunol (Paris).— 1991,— Vol.23, No 4.— P.135—142.</mixed-citation><mixed-citation xml:lang="en">Le Roux P., Le Luyer B. Accelerated desensitization to Dermatophagoides pteronissinus mites in children with asthma. Results of two years of immunotherapy / / Allerg. Immunol (Paris).— 1991,— Vol.23, No 4.— P.135—142.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Leroy B.P., Lachapelle J.M., Somville M.M., Saint-Remy J.M. Injection of allergen-antibody complexes is an effective of atopic dermatitis [see comments] / / Dermatológica.— 1991.— Vol. 182, No2.— P.98—106.</mixed-citation><mixed-citation xml:lang="en">Leroy B.P., Lachapelle J.M., Somville M.M., Saint-Remy J.M. Injection of allergen-antibody complexes is an effective of atopic dermatitis [see comments] / / Dermatológica.— 1991.— Vol. 182, No2.— P.98—106.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Lilja G., Sundín B., Graff-Lonneuig V., Hedlin G., Heilborn H., Norrlind K., Pegelow K.-O., Lowenstein H. Immunotherapy with cat and dog-dander extracts. IY. Effect of 2 years of treatment / / J. Allergy Clin. Immunol.— 1989.— Vol.83, No 1.— P .37—44.</mixed-citation><mixed-citation xml:lang="en">Lilja G., Sundín B., Graff-Lonneuig V., Hedlin G., Heilborn H., Norrlind K., Pegelow K.-O., Lowenstein H. Immunotherapy with cat and dog-dander extracts. IY. Effect of 2 years of treatment / / J. Allergy Clin. Immunol.— 1989.— Vol.83, No 1.— P .37—44.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Loidolt D., Vassella C.C., de Week A.L., Stadler B.M. The clinical significance of anti-IgE antibodies in the treatment of allergic rhinopathy / / Laryngorhinootologie.— 1990.— Vol.69, No 5.— P.255—259.</mixed-citation><mixed-citation xml:lang="en">Loidolt D., Vassella C.C., de Week A.L., Stadler B.M. The clinical significance of anti-IgE antibodies in the treatment of allergic rhinopathy / / Laryngorhinootologie.— 1990.— Vol.69, No 5.— P.255—259.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Machiels J.J., Somville M.A., Lebrun P.M., Lebecque S.J., Jacquemin M.G., Saint-Remy J.M.R. Allergic bronchial asthma due to Dermatophagoides pteronissinus can be efficiently treated by inoculation of allergen-antibody complexes / / J. Clin. Invest.— 1990.— Vol.85.— P. 1024—1035.</mixed-citation><mixed-citation xml:lang="en">Machiels J.J., Somville M.A., Lebrun P.M., Lebecque S.J., Jacquemin M.G., Saint-Remy J.M.R. Allergic bronchial asthma due to Dermatophagoides pteronissinus can be efficiently treated by inoculation of allergen-antibody complexes / / J. Clin. Invest.— 1990.— Vol.85.— P. 1024—1035.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Machiels J.J., Somville M.A., Jacquemin M.G., Saint-Remy J.M.R. Allergen-antibody complexes can efficiently prevent seasonal rhinitis and asthma in grass pollen hypersensitive patients. Allergen-antibody complex immunotherapy / / Allergy.— 1990.— Vol.45, No 5.— P .335—348.</mixed-citation><mixed-citation xml:lang="en">Machiels J.J., Somville M.A., Jacquemin M.G., Saint-Remy J.M.R. Allergen-antibody complexes can efficiently prevent seasonal rhinitis and asthma in grass pollen hypersensitive patients. Allergen-antibody complex immunotherapy / / Allergy.— 1990.— Vol.45, No 5.— P .335—348.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Mailing H.J., Skov P., Stahl K. Diagnosis and immunotherapy of mould allergy / / Ibid.— 1988.— Vol.43, No 3.— P .228—238.</mixed-citation><mixed-citation xml:lang="en">Mailing H.J., Skov P., Stahl K. Diagnosis and immunotherapy of mould allergy / / Ibid.— 1988.— Vol.43, No 3.— P .228—238.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Mailing H.J. Immunotherapy with Cladosporium herbarum / / Immunotherapy / Eds. U.G. Svendsen, H.J. Malling.-Kobenhavn, 1989.— P.39—47.</mixed-citation><mixed-citation xml:lang="en">Mailing H.J. Immunotherapy with Cladosporium herbarum / / Immunotherapy / Eds. U.G. Svendsen, H.J. Malling.-Kobenhavn, 1989.— P.39—47.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">McHugh S.M., Ewan P.W. Reduction of increased serum neutrophil chemotactic activity following effective hyposensitization in house dust mite allergy / / Clin. Exp. Allergy.— 1989.— Vol. 19.— P.327—334.</mixed-citation><mixed-citation xml:lang="en">McHugh S.M., Ewan P.W. Reduction of increased serum neutrophil chemotactic activity following effective hyposensitization in house dust mite allergy / / Clin. Exp. Allergy.— 1989.— Vol. 19.— P.327—334.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Mosbech H. Who will benefit from immunotherapy / / Immunotherapy / Eds. U.G. Svendsen, H.J. Malling.-Kobenhavn, 1989.— P .89—91.</mixed-citation><mixed-citation xml:lang="en">Mosbech H. Who will benefit from immunotherapy / / Immunotherapy / Eds. U.G. Svendsen, H.J. Malling.-Kobenhavn, 1989.— P .89—91.</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Mosbech H., Djurup R., Dreborg S., Poulsen L.K., Skov P.S., Steringer I. Hyposensitization in asthmatics with mPEG-modified and unmodified house dust mite extract. III. Effect on mite-specific immunological parameters and correlation to change in mite-sen- sitivity and symptoms / / Allergy.— 1990.— Vol.45, No 2.— P.130—141.</mixed-citation><mixed-citation xml:lang="en">Mosbech H., Djurup R., Dreborg S., Poulsen L.K., Skov P.S., Steringer I. Hyposensitization in asthmatics with mPEG-modified and unmodified house dust mite extract. III. Effect on mite-specific immunological parameters and correlation to change in mite-sen- sitivity and symptoms / / Allergy.— 1990.— Vol.45, No 2.— P.130—141.</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Muller ü., Berchtold E., Helbing A. Honeybee venom allergy: results of a sting challenge 1 year after stopping successful venom immunotherapy in 86 patients / / J. Allergy Clin. Immunol.— 1991. _ Vol.87, No 3.— P .702—709.</mixed-citation><mixed-citation xml:lang="en">Muller ü., Berchtold E., Helbing A. Honeybee venom allergy: results of a sting challenge 1 year after stopping successful venom immunotherapy in 86 patients / / J. Allergy Clin. Immunol.— 1991. _ Vol.87, No 3.— P .702—709.</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Naclerio R.M., Proud D., Togias A., Adkinson N.F., Jr., Meyers D.A., Norman P.S., Lichtenstein L.M. Inflammatory mediators in late antigen-induced rhinitis / / N. Engl. J. M ed.— 1985.— Vol.313.— P .65—70.</mixed-citation><mixed-citation xml:lang="en">Naclerio R.M., Proud D., Togias A., Adkinson N.F., Jr., Meyers D.A., Norman P.S., Lichtenstein L.M. Inflammatory mediators in late antigen-induced rhinitis / / N. Engl. J. M ed.— 1985.— Vol.313.— P .65—70.</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">O’Hehir R.E., Mach B., Berte C., Bai V., Quint D. Direct evidence for a functional role of HLA-DRB3 gene products in the recognition of Dermatophagoides spp by helper T cell clones / / Int. Immunol.— 1990.— Vol.2.— P .885—892.</mixed-citation><mixed-citation xml:lang="en">O’Hehir R.E., Mach B., Berte C., Bai V., Quint D. Direct evidence for a functional role of HLA-DRB3 gene products in the recognition of Dermatophagoides spp by helper T cell clones / / Int. Immunol.— 1990.— Vol.2.— P .885—892.</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">O'Hehir R.E., Busch R., Rothbard J.B., Lamb J.R. An in vitro model of peptide-mediated immunomodulation of the human T cell response to Dermatophagoides spp (house dust mite) / / J. Allergy Clin. Immunol.— 1991.— Vol.87.— P.1120—1127.</mixed-citation><mixed-citation xml:lang="en">O'Hehir R.E., Busch R., Rothbard J.B., Lamb J.R. An in vitro model of peptide-mediated immunomodulation of the human T cell response to Dermatophagoides spp (house dust mite) / / J. Allergy Clin. Immunol.— 1991.— Vol.87.— P.1120—1127.</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Ohman J.L., Findlay S.R., Leitermann K.M. Immunotherapy in cat-induced asthma. Double-blind trial with evaluation of in vivo and in vitro resposes / / Ibid.— 1984.— Vol.74, No 5.— P.230—239.</mixed-citation><mixed-citation xml:lang="en">Ohman J.L., Findlay S.R., Leitermann K.M. Immunotherapy in cat-induced asthma. Double-blind trial with evaluation of in vivo and in vitro resposes / / Ibid.— 1984.— Vol.74, No 5.— P.230—239.</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Paty E., de Blic J., Brunet D., Le Bourgeois M., Garcelon M., Paupe J., Scheinmann P. Accelerated desensitization with Dermatophagoides pteronissinus in severe asthmatic children. Evaluation after one year of immunotherapy / / Arch. Fr. Pediatr.— 1990.— Vol.47, No 3.— P .173—179.</mixed-citation><mixed-citation xml:lang="en">Paty E., de Blic J., Brunet D., Le Bourgeois M., Garcelon M., Paupe J., Scheinmann P. Accelerated desensitization with Dermatophagoides pteronissinus in severe asthmatic children. Evaluation after one year of immunotherapy / / Arch. Fr. Pediatr.— 1990.— Vol.47, No 3.— P .173—179.</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Persson C.G.A., Svensson C., Greiff L. et al. The use of the nose to study the inflammatory response of the respiratory tract / / Thorax.— 1992.— Vol.47.— P .993—1000.</mixed-citation><mixed-citation xml:lang="en">Persson C.G.A., Svensson C., Greiff L. et al. The use of the nose to study the inflammatory response of the respiratory tract / / Thorax.— 1992.— Vol.47.— P .993—1000.</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Rak S. The effect of immunotherapy on primary and secondary bronchial hyperresponsiveness in patients with seasonal asthma / / Immunotherapy / Eds. U. G. Svendsen, H.J.Malling.-Kobenhavn, 1989.— P.77—87.</mixed-citation><mixed-citation xml:lang="en">Rak S. The effect of immunotherapy on primary and secondary bronchial hyperresponsiveness in patients with seasonal asthma / / Immunotherapy / Eds. U. G. Svendsen, H.J.Malling.-Kobenhavn, 1989.— P.77—87.</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Rak S., Bjornson A., Hakanson L., Sorenson S., Venge P. The effect of immunotherapy on eosinophil accumulation and production of eosinophil chemotactic activity in the lung of subjects with asthma during natural pollen exposure / / J. Allergy Clin. Immunol.— 1991.— Vol.88, No 6.— P.878—888.</mixed-citation><mixed-citation xml:lang="en">Rak S., Bjornson A., Hakanson L., Sorenson S., Venge P. The effect of immunotherapy on eosinophil accumulation and production of eosinophil chemotactic activity in the lung of subjects with asthma during natural pollen exposure / / J. Allergy Clin. Immunol.— 1991.— Vol.88, No 6.— P.878—888.</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">Robinson D.S., Hamid Q., Ying S., Tsicopoulos A., Barkans J., Bentley A.M., Corrigan C., Durham S.R., Kay A.B. Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma / / N. Engl. J. Med.— 1992.— Vol.326.— P.298—304.</mixed-citation><mixed-citation xml:lang="en">Robinson D.S., Hamid Q., Ying S., Tsicopoulos A., Barkans J., Bentley A.M., Corrigan C., Durham S.R., Kay A.B. Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma / / N. Engl. J. Med.— 1992.— Vol.326.— P.298—304.</mixed-citation></citation-alternatives></ref><ref id="cit64"><label>64</label><citation-alternatives><mixed-citation xml:lang="ru">Robinson D.S., Bentley A.M., Hartnell A., Barkans J., Corrigan C., Durham S.R., Kay A.B. Activated memory T helper cells in bronchoalveolar lavage fluid from patients with atopic asthma: relation to asthma symptoms, lung function, and bronchial responsiveness / / Thorax.— 1993.— Vol.48.— P.26—32.</mixed-citation><mixed-citation xml:lang="en">Robinson D.S., Bentley A.M., Hartnell A., Barkans J., Corrigan C., Durham S.R., Kay A.B. Activated memory T helper cells in bronchoalveolar lavage fluid from patients with atopic asthma: relation to asthma symptoms, lung function, and bronchial responsiveness / / Thorax.— 1993.— Vol.48.— P.26—32.</mixed-citation></citation-alternatives></ref><ref id="cit65"><label>65</label><citation-alternatives><mixed-citation xml:lang="ru">Romagnani S. Induction of T1 and T2 responses: a key role for the “natural” immune response? / / Immunol. Today.— 1992.— Vol 13, No. 10.— P.379—381.</mixed-citation><mixed-citation xml:lang="en">Romagnani S. Induction of T1 and T2 responses: a key role for the “natural” immune response? / / Immunol. Today.— 1992.— Vol 13, No. 10.— P.379—381.</mixed-citation></citation-alternatives></ref><ref id="cit66"><label>66</label><citation-alternatives><mixed-citation xml:lang="ru">Saint-Remy J.-M.R. Immunotherapy of allergic diseases: A forthcoming therapy / / Acta Clin. Belg.— 1989.— Vol.44, No 6.— P .369—376.</mixed-citation><mixed-citation xml:lang="en">Saint-Remy J.-M.R. Immunotherapy of allergic diseases: A forthcoming therapy / / Acta Clin. Belg.— 1989.— Vol.44, No 6.— P .369—376.</mixed-citation></citation-alternatives></ref><ref id="cit67"><label>67</label><citation-alternatives><mixed-citation xml:lang="ru">Sehon A.H. Carl Prausnitz Memorial lecture. Supression of antibody responses by chemically modified antigens / / Int. Arch. Allergy Appl. Immunol.— 1991.— Vol.94, No 1—4.— P .11—20.</mixed-citation><mixed-citation xml:lang="en">Sehon A.H. Carl Prausnitz Memorial lecture. Supression of antibody responses by chemically modified antigens / / Int. Arch. Allergy Appl. Immunol.— 1991.— Vol.94, No 1—4.— P .11—20.</mixed-citation></citation-alternatives></ref><ref id="cit68"><label>68</label><citation-alternatives><mixed-citation xml:lang="ru">Stadler B.M. A new concept for human IgE regulation / / ACI News.— 1991.— Vol.3, No 2.— P.53—57.</mixed-citation><mixed-citation xml:lang="en">Stadler B.M. A new concept for human IgE regulation / / ACI News.— 1991.— Vol.3, No 2.— P.53—57.</mixed-citation></citation-alternatives></ref><ref id="cit69"><label>69</label><citation-alternatives><mixed-citation xml:lang="ru">Stanworth D.R., Jones V.M., Lewin I.V., Nayyar S. Allergy treatment with a peptide vaccine / / Lancet.— 1990.— Vol.336.— P .1279— 1281.</mixed-citation><mixed-citation xml:lang="en">Stanworth D.R., Jones V.M., Lewin I.V., Nayyar S. Allergy treatment with a peptide vaccine / / Lancet.— 1990.— Vol.336.— P .1279— 1281.</mixed-citation></citation-alternatives></ref><ref id="cit70"><label>70</label><citation-alternatives><mixed-citation xml:lang="ru">Tamir R., Castracane J.M., Rocklin R.E. Generation of supressor cells in atopic patients during immunotherapy that modulate IgE synthesis / / J. Allergy Clin. Immunol.— 1987.— Vol.79.— P .591—598.</mixed-citation><mixed-citation xml:lang="en">Tamir R., Castracane J.M., Rocklin R.E. Generation of supressor cells in atopic patients during immunotherapy that modulate IgE synthesis / / J. Allergy Clin. Immunol.— 1987.— Vol.79.— P .591—598.</mixed-citation></citation-alternatives></ref><ref id="cit71"><label>71</label><citation-alternatives><mixed-citation xml:lang="ru">Thompson R.A. (Ed.), Bousquet J., Cohen S., Frei P.C., Jager L., Lambert P.H., LessofM.H., Loblay R.H., Mailing H.-J., Norman P.S., de Week A.L., Weeke B. The current status of allergen immunotherapy (hyposensitization). Report of a WHO/IUIS working group / / Allergy.— 1989.— Vol.44, No 10.— P.369—379.</mixed-citation><mixed-citation xml:lang="en">Thompson R.A. (Ed.), Bousquet J., Cohen S., Frei P.C., Jager L., Lambert P.H., LessofM.H., Loblay R.H., Mailing H.-J., Norman P.S., de Week A.L., Weeke B. The current status of allergen immunotherapy (hyposensitization). Report of a WHO/IUIS working group / / Allergy.— 1989.— Vol.44, No 10.— P.369—379.</mixed-citation></citation-alternatives></ref><ref id="cit72"><label>72</label><citation-alternatives><mixed-citation xml:lang="ru">Turkeltaub P.C. The importance of allergen dose on the safety and efficacy of immunotherapy of ragweed hay fever with standardised short ragweed extracts (Abstract) / / J. Allergy Clin. Immunol.— 1986.— Vol.77.— P.211.</mixed-citation><mixed-citation xml:lang="en">Turkeltaub P.C. The importance of allergen dose on the safety and efficacy of immunotherapy of ragweed hay fever with standardised short ragweed extracts (Abstract) / / J. Allergy Clin. Immunol.— 1986.— Vol.77.— P.211.</mixed-citation></citation-alternatives></ref><ref id="cit73"><label>73</label><citation-alternatives><mixed-citation xml:lang="ru">Van Bever H.P., Stevens W.J. Suppression of the late asthmatic reaction by hyposensitisation in asthmatic children allergic to house dust mite (Dermatophagoides pteronyssinus) / / Clin. Exp. Allergy.— 1989.— Vol. 19(4), No 7.— P.399—404.</mixed-citation><mixed-citation xml:lang="en">Van Bever H.P., Stevens W.J. Suppression of the late asthmatic reaction by hyposensitisation in asthmatic children allergic to house dust mite (Dermatophagoides pteronyssinus) / / Clin. Exp. Allergy.— 1989.— Vol. 19(4), No 7.— P.399—404.</mixed-citation></citation-alternatives></ref><ref id="cit74"><label>74</label><citation-alternatives><mixed-citation xml:lang="ru">Van Metre T.E., Adkinson N.F., Amodio F.J., Kagey-Sobotka A., Norman P.S. A comparative study of the effectiveness of the Rinkel method and the current standard method of immunotherapy for ragweed pollen hay fever / / J. Allergy Clin. Immunol.— 1979.— Vol.66.— P.500—513.</mixed-citation><mixed-citation xml:lang="en">Van Metre T.E., Adkinson N.F., Amodio F.J., Kagey-Sobotka A., Norman P.S. A comparative study of the effectiveness of the Rinkel method and the current standard method of immunotherapy for ragweed pollen hay fever / / J. Allergy Clin. Immunol.— 1979.— Vol.66.— P.500—513.</mixed-citation></citation-alternatives></ref><ref id="cit75"><label>75</label><citation-alternatives><mixed-citation xml:lang="ru">Van Metre T.E., Marsh D.G., Adkinspn N.F., Kagey-Sobotka A., Khattignavong A., Norman P.S., Rosenberg G.L. Immunotherapy for cat asthma / / Ibid.— 1988.— Vol.82.— P. 1055—1068.</mixed-citation><mixed-citation xml:lang="en">Van Metre T.E., Marsh D.G., Adkinspn N.F., Kagey-Sobotka A., Khattignavong A., Norman P.S., Rosenberg G.L. Immunotherapy for cat asthma / / Ibid.— 1988.— Vol.82.— P. 1055—1068.</mixed-citation></citation-alternatives></ref><ref id="cit76"><label>76</label><citation-alternatives><mixed-citation xml:lang="ru">Varney V.A., Gaga M., Frew A.J., Aber V.R., Kay A.B., Durham S.R. Usefulness of immunotherapy in patients with severe summer hay fever uncontrolled by antiallergic drugs / / Br. Med. J.— 1991.— Vol.302, No. 6771.— P.265—269.</mixed-citation><mixed-citation xml:lang="en">Varney V.A., Gaga M., Frew A.J., Aber V.R., Kay A.B., Durham S.R. Usefulness of immunotherapy in patients with severe summer hay fever uncontrolled by antiallergic drugs / / Br. Med. J.— 1991.— Vol.302, No. 6771.— P.265—269.</mixed-citation></citation-alternatives></ref><ref id="cit77"><label>77</label><citation-alternatives><mixed-citation xml:lang="ru">Vervloet D., van der Brempt X., Charpin D., Sirnbaum J. Immunotherapy in allergic respiratory diseases / / Lung.— 1990.— Vol. 168, Suppl.— P .1013—1024.</mixed-citation><mixed-citation xml:lang="en">Vervloet D., van der Brempt X., Charpin D., Sirnbaum J. Immunotherapy in allergic respiratory diseases / / Lung.— 1990.— Vol. 168, Suppl.— P .1013—1024.</mixed-citation></citation-alternatives></ref><ref id="cit78"><label>78</label><citation-alternatives><mixed-citation xml:lang="ru">Warner J.O. Scientific theories of immunotherapy / / Selection of Allergic Patients for Immunotherapy. Proceeding 2-nd BRL Kurhaus Workshop on Allergy.-Scheveningen, 1988.— P.51—62.</mixed-citation><mixed-citation xml:lang="en">Warner J.O. Scientific theories of immunotherapy / / Selection of Allergic Patients for Immunotherapy. Proceeding 2-nd BRL Kurhaus Workshop on Allergy.-Scheveningen, 1988.— P.51—62.</mixed-citation></citation-alternatives></ref><ref id="cit79"><label>79</label><citation-alternatives><mixed-citation xml:lang="ru">Youlten L.J.F. Immunotherapy — treatment schedules and allergenic formulations / / Ibid.— P .37—40.</mixed-citation><mixed-citation xml:lang="en">Youlten L.J.F. Immunotherapy — treatment schedules and allergenic formulations / / Ibid.— P .37—40.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
