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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pulmo</journal-id><journal-title-group><journal-title xml:lang="ru">Пульмонология</journal-title><trans-title-group xml:lang="en"><trans-title>PULMONOLOGIYA</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-0189</issn><issn pub-type="epub">2541-9617</issn><publisher><publisher-name>Scientific and Practical Journal “PULMONOLOGIYA” LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pulmo-3632</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Эффективность специфической иммунотерапии у детей с заболеваниями респираторного тракта, обусловленными клещевой сенсибилизацией</article-title><trans-title-group xml:lang="en"><trans-title>The efficiency of specific immunotherapy in children with respiratory tractus diseases caused by sensitization to domestic mites</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гервазиева</surname><given-names>В. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Gervasieva</surname><given-names>V. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p><p>Чебоксары</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петрова</surname><given-names>Т. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrova</surname><given-names>T. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p><p>Чебоксары</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Агафонов</surname><given-names>В. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Agafonov</surname><given-names>V. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>МоскваЧебоксары</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>НИИ вакцин и сывороток им. И.И. Мечникова РАМН; Чувашский госуниверситет им. И.Н. Ульянова</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>1994</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>1994</year></pub-date><volume>0</volume><issue>4</issue><fpage>26</fpage><lpage>31</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гервазиева В.Б., Петрова Т.И., Агафонов В.Е., 1994</copyright-statement><copyright-year>1994</copyright-year><copyright-holder xml:lang="ru">Гервазиева В.Б., Петрова Т.И., Агафонов В.Е.</copyright-holder><copyright-holder xml:lang="en">Gervasieva V.B., Petrova T.I., Agafonov V.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.pulmonology.ru/pulm/article/view/3632">https://journal.pulmonology.ru/pulm/article/view/3632</self-uri><abstract><p>Была показана эффективность специфической иммунотерапии аллергических заболеваний у детей, чувствительных к домашним клещам. Эффективность лечения была выявлена по регрессии клинических симптомов, по снижению общего уровня LgЕ и по увеличению уровней аллерген-спeцифичных LgG и LgG4 антител. Лечение давало положительные результаты у 85,99% больных. Исследование доказывает, что до принятия решения об использовании специфичной иммунотерапии необходимо проводить обследование пациентов с использованием клинических, иммунологических и акарологических методов.</p></abstract><trans-abstract xml:lang="en"><p>The efficiency of specific immunotherapy of allergical diseases in mite-sensitized children was shown. The effectiveness of the treatment was manifested by the regression of clinical symptoms, the decrease of the total IgE level, and the increase of levels of IgG and IgG4 allergen-specific antibodies. The treatment gave positive results in 85.99% of patients. 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