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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pulmo</journal-id><journal-title-group><journal-title xml:lang="ru">Пульмонология</journal-title><trans-title-group xml:lang="en"><trans-title>PULMONOLOGIYA</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-0189</issn><issn pub-type="epub">2541-9617</issn><publisher><publisher-name>Scientific and Practical Journal “PULMONOLOGIYA” LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pulmo-3583</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Эф­фективность беродуала у детей с бронхиальной астмой</article-title><trans-title-group xml:lang="en"><trans-title>The Berodual effectivity in children with bronchial asthma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балаболкин</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Balabolkin</surname><given-names>I. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ширяева</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shiriaeva</surname><given-names>I. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Реутова</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Reutova</surname><given-names>V. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рылеева</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Rileeva</surname><given-names>I. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Намазова</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Namazova</surname><given-names>L. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Герасимова</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gerasimova</surname><given-names>J. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юсупов</surname><given-names>Г. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yusupov</surname><given-names>G. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>НИИ педиатрии Российской АМН</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>1994</year></pub-date><pub-date pub-type="epub"><day>30</day><month>06</month><year>1994</year></pub-date><volume>0</volume><issue>2</issue><fpage>39</fpage><lpage>43</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Балаболкин И.И., Ширяева И.С., Реутова В.С., Рылеева И.В., Намазова Л.С., Герасимова Ю.В., Юсупов Г.А., 1994</copyright-statement><copyright-year>1994</copyright-year><copyright-holder xml:lang="ru">Балаболкин И.И., Ширяева И.С., Реутова В.С., Рылеева И.В., Намазова Л.С., Герасимова Ю.В., Юсупов Г.А.</copyright-holder><copyright-holder xml:lang="en">Balabolkin I.I., Shiriaeva I.S., Reutova V.S., Rileeva I.V., Namazova L.S., Gerasimova J.V., Yusupov G.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.pulmonology.ru/pulm/article/view/3583">https://journal.pulmonology.ru/pulm/article/view/3583</self-uri><abstract><p>Авторами проведено изучение терапевтической эффективности беродуала у 77 детей с бронхиальной астмой. Выявлена высокая эффективность препарата в целях снятия приступов бронхиальной астмы и достижения ремиссии болезни. Отмечаемое под влиянием беродуала обратное развитие проявлений бронхиальной астмы сопровождается восстановлением бронхиальной проходимости, увеличением концентрации цАМФ, снижением уровня цГМФ и повышением активной аденилатциклазы в лейкоцитах.</p></abstract><trans-abstract xml:lang="en"><p>The therapeutic effectivity of Berodual in 77 children with bronchial asthma was studied. The high effectivity of the drug in the decline of asthma attacks and in the disease remission achievement was revealed. Under the Berodual influence, regression of bronchial asthma is accompanied by reparation of the bronchial pass, by the increase of the cAMP concentration, by the decrease of the cGMP level, and by the increase of active adenilatcyclase in leukocytes.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Вондра В. / / Новые терапевтические возможности лечения бронхиальной обструкции.— М., 1984.— С.14—21.</mixed-citation><mixed-citation xml:lang="en">Вондра В. / / Новые терапевтические возможности лечения бронхиальной обструкции.— М., 1984.— С.14—21.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Замотаев И.В., Мотузка И.М., Сельверстова Н.М. / / Современные методы лечения и профилактики бронхиальной астмы.— Л., 1985.— С.158—161.</mixed-citation><mixed-citation xml:lang="en">Замотаев И.В., Мотузка И.М., Сельверстова Н.М. / / Современные методы лечения и профилактики бронхиальной астмы.— Л., 1985.— С.158—161.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Молотков В.И. / / Клин. мед.— 1980.— No 4.— С.40—43.</mixed-citation><mixed-citation xml:lang="en">Молотков В.И. / / Клин. мед.— 1980.— No 4.— С.40—43.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Харпокурт К. / / Новые терапевтические возможности лечения бронхиальной обструкции.— М., 1984.— С.24—30.</mixed-citation><mixed-citation xml:lang="en">Харпокурт К. / / Новые терапевтические возможности лечения бронхиальной обструкции.— М., 1984.— С.24—30.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Чучалин А.Г. 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