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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pulmo</journal-id><journal-title-group><journal-title xml:lang="ru">Пульмонология</journal-title><trans-title-group xml:lang="en"><trans-title>PULMONOLOGIYA</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-0189</issn><issn pub-type="epub">2541-9617</issn><publisher><publisher-name>Scientific and Practical Journal “PULMONOLOGIYA” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18093/0869-0189-2022-32-5-728-736</article-id><article-id custom-type="elpub" pub-id-type="custom">pulmo-3491</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Влияние физической реабилитации в постковидном периоде на переносимость физической нагрузки: результаты открытого контролируемого исследования</article-title><trans-title-group xml:lang="en"><trans-title>Effects of physical rehabilitation on exercise tolerance in post-COVID patients: results of an open controlled trial</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5536-9388</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чикина</surname><given-names>С. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Chikina</surname><given-names>S. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чикина Светлана Юрьевна — кандидат медицинских наук, заведующая пульмонологическим отделением общества с ограниченной ответственностью «Интеграмед», ассистент кафедры пульмонологии Института клинической медицины им. Н.В.Склифосовского Федерального государственного автономного образовательного учреждения высшего образования «Первый московский государственный медицинский университет имени И.М.Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский Университет)</p><p>107023, Москва, Мажоров пер., 7–7А, стр. 8, </p><p>119991, Москва, ул. Трубецкая, 8, стр. 2 </p></bio><bio xml:lang="en"><p>Svetlana Yu. Chikina, Candidate of Medicine, Head of Pulmonology Department, Integramed LLC, Assistant Lecturer, Federal State Autonomous Educational Institution of Higher Education I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)</p><p>Mazhorov per. 7–7A, build. 8, Moscow, 107023, </p><p>ul. Trubetskaya 8, build. 2, Moscow, 119991</p></bio><email xlink:type="simple">clinic@integramed.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0658-4871</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кулешов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuleshov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кулешов Андрей Владимирович — кандидат медицинских наук, главный врач </p><p>107023, Москва, Мажоров пер., 7–7А, стр. 8</p></bio><bio xml:lang="en"><p>Andrey V. Kuleshov, Candidate of Medicine, Hospital Chief Executive Officer</p><p>Mazhorov per. 7–7A, build. 8, Moscow, 107023</p></bio><email xlink:type="simple">kuleshov@integramed.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитина</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitina</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Никитина Наталия Владимировна — заместитель главного врача по лечебной работе </p><p>107023, Москва, Мажоров пер., 7–7А, стр. 8</p></bio><bio xml:lang="en"><p>Nataliya V. Nikitina — Deputy Director for Clinical Care</p><p>Mazhorov per. 7–7A, build. 8, Moscow, 107023</p></bio><email xlink:type="simple">clinic@integramed.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1757-4137</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мещерякова</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Meshcheryakova</surname><given-names>N. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мещерякова Наталия Николаевна — кандидат медицинских наук, врач-пульмонолог общества с ограниченной ответственностью «Интеграмед», доцент кафедры пульмонологии факультета дополнительного профессионального образования Федерального государственного автономного образовательного учреждения высшего образования «Российский национальный исследовательский медицинский университет имени Н.И.Пирогова» Министерства здравоохранения Российской Федерации</p><p>107023, Москва, Мажоров пер., 7–7А, стр. 8, </p><p>117997, Москва, ул. Островитянова, 1 </p></bio><bio xml:lang="en"><p>Nataliya N. Meshcheryakova, Candidate of Medicine, pulmonologist, Integramed LLC, Associate Professor, Department of Pulmonology, Faculty of Postgraduate Physician Training, Pirogov Russian National Research Medical University (Pirogov Medical University), Ministry of Health of the Russian Federation</p><p>Mazhorov per. 7–7A, build. 8, Moscow, 107023, </p><p>ul. Ostrovityanova 1, Moscow, 117997</p></bio><email xlink:type="simple">clinic@integramed.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Общество с ограниченной ответственностью «Интеграмед»;&#13;
Федеральное государственное автономное образовательное учреждение высшего образования «Первый московский государственный медицинский университет имени И.М.Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Limited Liability Company “Integramed”;&#13;
Federal State Autonomous Educational Institution of Higher Education I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Общество с ограниченной ответственностью «Интеграмед»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Limited Liability Company “Integramed”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Общество с ограниченной ответственностью «Интеграмед»;&#13;
Федеральное государственное автономное образовательное учреждение высшего образования «Российский национальный исследовательский медицинский университет имени Н.И.Пирогова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Limited Liability Company “Integramed”;&#13;
Pirogov Russian National Research Medical University (Pirogov Medical University), Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>10</day><month>10</month><year>2022</year></pub-date><volume>32</volume><issue>5</issue><fpage>728</fpage><lpage>736</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чикина С.Ю., Кулешов А.В., Никитина Н.В., Мещерякова Н.Н., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Чикина С.Ю., Кулешов А.В., Никитина Н.В., Мещерякова Н.Н.</copyright-holder><copyright-holder xml:lang="en">Chikina S.Y., Kuleshov A.V., Nikitina N.V., Meshcheryakova N.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.pulmonology.ru/pulm/article/view/3491">https://journal.pulmonology.ru/pulm/article/view/3491</self-uri><abstract><p>В последние 2 года актуальна тема физической реабилитации больных, перенесших COronaVIrus Disease-19 (COVID-19) с поражением легких. Однако ее проведению в амбулаторных условиях посвящены единичные публикации.</p><p>Целью настоящего исследования явилось изучение эффективности физической реабилитации в лечении постковидного синдрома у пациентов, перенесших коронавирусную инфекцию с поражением легких.</p><sec><title>Материалы и методы</title><p>Материалы и методы. Выполнено нерандомизированное проспективное открытое контролируемое исследование. Пациенты, обратившиеся в клинику по поводу перенесенной коронавирусной инфекции COVID-19, осложненной вирусной пневмонией, направлялись на физическую реабилитацию в амбулаторных условиях под наблюдением медицинского персонала. Анализировались результаты 6-минутного шагового теста (6-МШТ), выраженность одышки по шкале Борга и насыщение гемоглобина артериальной крови кислородом (SpO2 ) до и после нагрузки.</p></sec><sec><title>Результаты</title><p>Результаты. Группу реабилитации составили 24 пациента, группу контроля – 6 больных. Исходные и демографические характеристики в обеих группах не имели достоверных различий. За период наблюдения в группе реабилитации достоверно увеличилось расстояние 6-МШТ (р = 0,000018), уменьшилась частота пульса в покое (р = 0,017) и после нагрузки (р = 0,017), улучшилась SpO2 в покое (р = 0,030) и после нагрузки (р = 0,0021), уменьшилась одышка в конце нагрузки (р = 0,017). В группе контроля ни один из исследуемых показателей статистически достоверно не изменился. В группе реабилитации, по сравнению с контрольной, в конце периода наблюдения среднее расстояние в 6-МШТ увеличилось на 63,2 ± 36,3 м по сравнению с исходным 14,0 ± 28,8 м (р = 0,01), нарастание одышки во время 6-МШТ было менее выраженным (0 (0–1) баллов vs 1 (1–2) балл соответственно; р = 0,033).</p></sec><sec><title>Заключение</title><p>Заключение. Физическая реабилитация в амбулаторных условиях под наблюдением медицинского персонала ускоряет восстановление физической толерантности пациентов, перенесших COVID-19 с поражением легких.</p></sec></abstract><trans-abstract xml:lang="en"><p>The issue of physical rehabilitation of post-COVID patients stays relevant up to this day. Most publications discuss inpatient rehabilitation and only few publications describe outpatient physical rehabilitation of such patients.</p><sec><title>The aim</title><p>The aim. Our study was performed to investigate efficacy of outpatient physical rehabilitation of post-COVID patients with lung injury.</p></sec><sec><title>Methods</title><p>Methods. This was a prospective non-randomized open controlled study. All patients with COVID-19-associated lung injury were referred to supervised outpatient rehabilitation program. We analyzed 6-minute walk test (6-MWT) results, evaluation of dyspnea using Borg scale and assessment of oxygen saturation (SpO2) using pulse oxymeter before and after walking.</p></sec><sec><title>Results</title><p>Results. The rehabilitation group included 24 patients and the control group included 6 patients. The baseline and demographic findings did not differ significantly between the groups. The 6-minute distance (6-MWD) (р = 0.000018), heat rate at rest (р = 0.017) and after walking (р = 0.017), dyspnea after walking (р = 0.017), oxygen saturation at rest (р = 0.030) and after walking (р = 0.0021) improved significantly in the rehabilitation group and did not change significantly in the control group. At the end of the study, 6-MWD increased by 63.2 ± 36.3 m in the rehabilitation group compared to 14.0 ± 28.8 m in the control group (р = 0,01) and exertional dyspnea score increased by 0 (0 – 1) compared to 1 (1 – 2) in the control group (p = 0.033).</p></sec><sec><title>Conclusion</title><p>Conclusion. Supervised outpatient physical rehabilitation in outpatient settings can accelerate physical recovery in post-COVID patients with lung injury.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19</kwd><kwd>физическая реабилитация</kwd><kwd>6-минутный шаговый тест</kwd><kwd>десатурация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>physical rehabilitation</kwd><kwd>6-minute walk test</kwd><kwd>desaturation</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">нет</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Singh S. Post-COVID-19 rehabilitation. In: Fabre A., Hurst J.R., Ramjug Sh., eds. COVID-19. Eur. Respir. Monograph. 2021: 197–213. DOI: 10.1183/2312508X.10024520.</mixed-citation><mixed-citation xml:lang="en">Singh S. Post-COVID-19 rehabilitation. In: Fabre A., Hurst J.R., Ramjug Sh., eds. COVID-19. Eur. 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