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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pulmo</journal-id><journal-title-group><journal-title xml:lang="ru">Пульмонология</journal-title><trans-title-group xml:lang="en"><trans-title>PULMONOLOGIYA</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-0189</issn><issn pub-type="epub">2541-9617</issn><publisher><publisher-name>Scientific and Practical Journal “PULMONOLOGIYA” LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pulmo-2913</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Клиника и лечение бронхиальной астмы, сочетающейся с гастроэзофагеальным рефлюксом</article-title><trans-title-group xml:lang="en"><trans-title>Clinical features and therapy of bronchial asthma associated with gastroesophageal reflux</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Медведев</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Medvedev</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шмелев</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Shmelev</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Центральный НИИ туберкулеза РАМН, городская клиническая больница № 11</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2002</year></pub-date><pub-date pub-type="epub"><day>23</day><month>10</month><year>2021</year></pub-date><volume>0</volume><issue>2</issue><fpage>22</fpage><lpage>27</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Медведев А.В., Шмелев Е.И., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Медведев А.В., Шмелев Е.И.</copyright-holder><copyright-holder xml:lang="en">Medvedev A.V., Shmelev E.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.pulmonology.ru/pulm/article/view/2913">https://journal.pulmonology.ru/pulm/article/view/2913</self-uri><abstract><p>Изучено значение гастроэзофагеального рефлюкса (ГЭР) в патогенезе и клинике бронхиальной астмы (БА). Обследованы 64 больных БА разной степени тяжести с клиническими признаками ГЭР. При суточном мониторировании pH пищевода установлена частота ГЭР при наличии диспепсических симптомов у больных БА. Установлена прямая зависимость выраженности респираторной симптоматики и ГЭР. Коррекция ГЭР вела к смягчению симптоматики БА, более быстрой ремиссии и снижению потребности в фармакотерапии БА.</p></abstract><trans-abstract xml:lang="en"><p>An importance of gastroesophageal reflux (GER) for the natural history and clinical presentation of bronchial asthma (BA) was studied. Sixty-four patients with different severity of bronchial asthma and clinical signs of GER were examined. When daily monitoring esophageal pH a frequency of GER was estimated in BA patients with indigestion. A direct correlation was found between respiratory symptoms’ severity and GER. GER correction led to a relief of BA signs, faster stabilization and reduction in need of medications for BA.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бейтугамова И.М., Чучалин А.Г . Рефлюкс-индуцированная бронхиальная астма. Рус. мед. журн. 1998; 6 (17): 1102-1107.</mixed-citation><mixed-citation xml:lang="en">Бейтугамова И.М., Чучалин А.Г . Рефлюкс-индуцированная бронхиальная астма. Рус. мед. журн. 1998; 6 (17): 1102-1107.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Глобальная инициатива по бронхиальной астме. Совместный доклад Национального института сердца, легких и крови и ВОЗ. Пульмонология 1996; Прил.: 48-59.</mixed-citation><mixed-citation xml:lang="en">Глобальная инициатива по бронхиальной астме. Совместный доклад Национального института сердца, легких и крови и ВОЗ. 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