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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pulmo</journal-id><journal-title-group><journal-title xml:lang="ru">Пульмонология</journal-title><trans-title-group xml:lang="en"><trans-title>PULMONOLOGIYA</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-0189</issn><issn pub-type="epub">2541-9617</issn><publisher><publisher-name>Scientific and Practical Journal “PULMONOLOGIYA” LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pulmo-2864</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LECTIONS</subject></subj-group></article-categories><title-group><article-title>Комбинированный препарат “симбикорт” и его место в терапии бронхиальной астмы</article-title><trans-title-group xml:lang="en"><trans-title>The combined drug “Simbikort” and its role in bronchial asthma therapy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Княжеская</surname><given-names>Н. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Knyazheskaya</surname><given-names>N. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра пульмонологии</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФУВ РГМУ</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2001</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2001</year></pub-date><volume>0</volume><issue>4</issue><fpage>118</fpage><lpage>122</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Княжеская Н.П., 2001</copyright-statement><copyright-year>2001</copyright-year><copyright-holder xml:lang="ru">Княжеская Н.П.</copyright-holder><copyright-holder xml:lang="en">Knyazheskaya N.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.pulmonology.ru/pulm/article/view/2864">https://journal.pulmonology.ru/pulm/article/view/2864</self-uri><abstract><p>.</p></abstract><trans-abstract xml:lang="en"><p>.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бронхиальная астма. Глобальная стратегия: совместный доклад Национального института Сердце, Легкие, Кровь и Всемирной организации здравоохранения. Русская версия под общ. ред. акад. А.Г.Чучалина. Пульмонология, 1996; прил.:1 — 165.</mixed-citation><mixed-citation xml:lang="en">Бронхиальная астма. Глобальная стратегия: совместный доклад Национального института Сердце, Легкие, Кровь и Всемирной организации здравоохранения. Русская версия под общ. ред. акад. А.Г.Чучалина. Пульмонология, 1996; прил.:1 — 165.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Бронхиальная астма. Руководство для врачей России (формулярная система). Там же, 1999; прил.: 1—40.</mixed-citation><mixed-citation xml:lang="en">Бронхиальная астма. Руководство для врачей России (формулярная система). Там же, 1999; прил.: 1—40.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Калманова Е.Н., Айсанов З.Р. Форадил и его место в терапии бронхиальной астмы. Там же, 2001; 1: 65—72.</mixed-citation><mixed-citation xml:lang="en">Калманова Е.Н., Айсанов З.Р. Форадил и его место в терапии бронхиальной астмы. Там же, 2001; 1: 65—72.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Формулярная система: лечение бронхиальной астмы. Астма.ru 0. 2001; 6—9.</mixed-citation><mixed-citation xml:lang="en">Формулярная система: лечение бронхиальной астмы. Астма.ru 0. 2001; 6—9.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Чучалин А.Г. Бронхиальная астма. М.; 1997, т.1—2.</mixed-citation><mixed-citation xml:lang="en">Чучалин А.Г. Бронхиальная астма. М.; 1997, т.1—2.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Agertoft L., Pedersen S. Effect of long-term treatment with inhaled biidesonide on adult height in children with asthma. N. Engl. J. Med. 2000; 343: 1064—1069.</mixed-citation><mixed-citation xml:lang="en">Agertoft L., Pedersen S. Effect of long-term treatment with inhaled biidesonide on adult height in children with asthma. N. Engl. J. Med. 2000; 343: 1064—1069.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Andersson F. et al. The costs and effects of adding formoterol to budesonide — results of the FACET Study. Am. J. Respir. Crit. Care Med. 1999; 159 (3, Pt.2): A762.</mixed-citation><mixed-citation xml:lang="en">Andersson F. et al. The costs and effects of adding formoterol to budesonide — results of the FACET Study. Am. J. Respir. Crit. Care Med. 1999; 159 (3, Pt.2): A762.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Anderson G.P. Formoterol: pharmacology, molecular basis of agonism, and mechanism of long duration of highly potent and selective agonist bronchodilatator. Life Sei. 1993; 52: 2145—2160.</mixed-citation><mixed-citation xml:lang="en">Anderson G.P. Formoterol: pharmacology, molecular basis of agonism, and mechanism of long duration of highly potent and selective agonist bronchodilatator. Life Sei. 1993; 52: 2145—2160.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Ankerst J., Persson G., Weibull E. A high dose of budesonide/formoterol in a single inhaler was well tolerated by asthmatic patients. Eur. Respir. J. 2000; 16 (suppl.31): 33s+poster.</mixed-citation><mixed-citation xml:lang="en">Ankerst J., Persson G., Weibull E. A high dose of budesonide/formoterol in a single inhaler was well tolerated by asthmatic patients. Eur. Respir. J. 2000; 16 (suppl.31): 33s+poster.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Barney P.G.J. Current questions in the epidemiology of asthma. In: Holgate S.Т., et al. Asthma: Physiology. Immunology, and Treatment. London: Academic Press; 1993. 3—25.</mixed-citation><mixed-citation xml:lang="en">Barney P.G.J. Current questions in the epidemiology of asthma. In: Holgate S.Т., et al. Asthma: Physiology. Immunology, and Treatment. London: Academic Press; 1993. 3—25.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Crisholm S. et al. Once-daily budesonide in mild asthma. Respir. Med. 1998; 92: 421—425.</mixed-citation><mixed-citation xml:lang="en">Crisholm S. et al. Once-daily budesonide in mild asthma. Respir. Med. 1998; 92: 421—425.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Juniper E.F., Svensson K., Byrne P.M. et al. Asthma quality of life during 1 year of treatment with budesonide with or without formoterol. Eur. Respir. J. 1999; 14: 1038—1043.</mixed-citation><mixed-citation xml:lang="en">Juniper E.F., Svensson K., Byrne P.M. et al. Asthma quality of life during 1 year of treatment with budesonide with or without formoterol. Eur. Respir. J. 1999; 14: 1038—1043.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Kips J.C., O’Connor B.J., Inman M.D. et al. A long-termed study of the antiinflammatory effect of low-dosed budesonide plus formoterol versus high-dosed budesonide in asthma. Am. Respir. Crit. Care Med. 2000; 161: 996—1001.</mixed-citation><mixed-citation xml:lang="en">Kips J.C., O’Connor B.J., Inman M.D. et al. A long-termed study of the antiinflammatory effect of low-dosed budesonide plus formoterol versus high-dosed budesonide in asthma. Am. Respir. Crit. Care Med. 2000; 161: 996—1001.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">McFadden E.R., Casale T.B., Edwards T.B. et al. Administration of budesonide once daily by means of Turbuhaler to subjects with stable asthma. J. Allergy Clin. Immunol. 1999; 104: 46—52.</mixed-citation><mixed-citation xml:lang="en">McFadden E.R., Casale T.B., Edwards T.B. et al. Administration of budesonide once daily by means of Turbuhaler to subjects with stable asthma. J. Allergy Clin. Immunol. 1999; 104: 46—52.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Miller-Larsson A. et. al. Prolonged airway activity and improved selectivity of budesonide possibly due to esterification. Am. J. Respir. Crit. Care Med. 2000; 162: 1455—1461.</mixed-citation><mixed-citation xml:lang="en">Miller-Larsson A. et. al. Prolonged airway activity and improved selectivity of budesonide possibly due to esterification. Am. J. Respir. Crit. Care Med. 2000; 162: 1455—1461.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Miller-Larsson A., Mattsson H., Hjertberg E., et al. Reversible fatty acid conjugation of budesonide: novel mechanism foe prolonged retention of topically applied steroid in airway tissue. Drug Metab. Dispos. 1998; 26: 623—630.</mixed-citation><mixed-citation xml:lang="en">Miller-Larsson A., Mattsson H., Hjertberg E., et al. Reversible fatty acid conjugation of budesonide: novel mechanism foe prolonged retention of topically applied steroid in airway tissue. Drug Metab. Dispos. 1998; 26: 623—630.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Molimard M. et al. Long- and short-adrenoreceptor agonists: interactions in human contracted bronchi. Eur. Respir. J. 1998; 11: 583—588.</mixed-citation><mixed-citation xml:lang="en">Molimard M. et al. Long- and short-adrenoreceptor agonists: interactions in human contracted bronchi. Eur. Respir. J. 1998; 11: 583—588.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">O’Connor B.J., Alkinan S.L., Barnes P.J. Tolerance to the non-bronchodilatator effects of inhaled ß2-agonists in asthma. N. Engl. J. Med. 1992; 327: 1204—1208.</mixed-citation><mixed-citation xml:lang="en">O’Connor B.J., Alkinan S.L., Barnes P.J. Tolerance to the non-bronchodilatator effects of inhaled ß2-agonists in asthma. N. Engl. J. Med. 1992; 327: 1204—1208.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Palmquist M. et al. Comparison of the relative efficacy of formoterol and salmeterol in asthmatic patients. Am. J. Respir. Crit. Care Med. 1999; 160: 244—249.</mixed-citation><mixed-citation xml:lang="en">Palmquist M. et al. Comparison of the relative efficacy of formoterol and salmeterol in asthmatic patients. Am. J. Respir. Crit. Care Med. 1999; 160: 244—249.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Palmquist M. et al. Inhaled dry powder formoterol and salmererol in asthmatic patients: onset of action, duration of effect and potency. Eur. Respir. J. 1997; 10: 2484—2489.</mixed-citation><mixed-citation xml:lang="en">Palmquist M. et al. Inhaled dry powder formoterol and salmererol in asthmatic patients: onset of action, duration of effect and potency. Eur. Respir. J. 1997; 10: 2484—2489.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Pauwels R.A. et al. Effect of inhaled formoterol and budesonide on exacerbations of asthma. N. Engl. J. Med. 1997; 337: 1405—1411.</mixed-citation><mixed-citation xml:lang="en">Pauwels R.A. et al. Effect of inhaled formoterol and budesonide on exacerbations of asthma. N. Engl. J. Med. 1997; 337: 1405—1411.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Pedersen S., O’Byrne P. A comparison of the efficacy and safety of inhaled corticosteroides in asthma. Allergy 1997; 52 (suppl.39): 1—34.</mixed-citation><mixed-citation xml:lang="en">Pedersen S., O’Byrne P. A comparison of the efficacy and safety of inhaled corticosteroides in asthma. Allergy 1997; 52 (suppl.39): 1—34.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Politiek M.J., Boorsma M., Aalbers R. Comparison of formoterol, salbutamol and salmeterol in methacholine-induced severe bronchoconstriction. Eur. Respir. J. 1999; 13: 988—992.</mixed-citation><mixed-citation xml:lang="en">Politiek M.J., Boorsma M., Aalbers R. Comparison of formoterol, salbutamol and salmeterol in methacholine-induced severe bronchoconstriction. Eur. Respir. J. 1999; 13: 988—992.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">The British Guidelines on Asthma Management. Thorax, 1997; 52 (suppl.l): 1—20.</mixed-citation><mixed-citation xml:lang="en">The British Guidelines on Asthma Management. Thorax, 1997; 52 (suppl.l): 1—20.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Woolcock A. et al. Comparison of addition of salmeterol to inhaled steroids with doubling of the dose of inhaled steroids. Am. J. Respir. Crit. Care Med. 1996; 153: 1481—1488.</mixed-citation><mixed-citation xml:lang="en">Woolcock A. et al. Comparison of addition of salmeterol to inhaled steroids with doubling of the dose of inhaled steroids. Am. J. Respir. Crit. Care Med. 1996; 153: 1481—1488.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
