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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pulmo</journal-id><journal-title-group><journal-title xml:lang="ru">Пульмонология</journal-title><trans-title-group xml:lang="en"><trans-title>PULMONOLOGIYA</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-0189</issn><issn pub-type="epub">2541-9617</issn><publisher><publisher-name>Scientific and Practical Journal “PULMONOLOGIYA” LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">pulmo-2589</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Спектральная туссофоиобарография — метод оценки обратимости бронхиальной обструкции у больных бронхиальной астмой</article-title><trans-title-group xml:lang="en"><trans-title>Spectral tussophonobarography as a method for evaluation of the airway obstruction reversibility in asthma patients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семенкова</surname><given-names>Г. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Semenkova</surname><given-names>G. G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Провоторов</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Provotorov</surname><given-names>V. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сычев</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sychyov</surname><given-names>V. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лозинская</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lozinskaya</surname><given-names>Yu. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Овсянников</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Ovsyannikov</surname><given-names>E. S.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Кафедра факультетской терапии Воронежской государственной медицинской академии им. Н.Н.Бурденко</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2003</year></pub-date><pub-date pub-type="epub"><day>02</day><month>09</month><year>2021</year></pub-date><volume>0</volume><issue>6</issue><fpage>32</fpage><lpage>36</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Семенкова Г.Г., Провоторов В.М., Сычев В.В., Лозинская Ю.А., Овсянников Е.С., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Семенкова Г.Г., Провоторов В.М., Сычев В.В., Лозинская Ю.А., Овсянников Е.С.</copyright-holder><copyright-holder xml:lang="en">Semenkova G.G., Provotorov V.M., Sychyov V.V., Lozinskaya Y.A., Ovsyannikov E.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.pulmonology.ru/pulm/article/view/2589">https://journal.pulmonology.ru/pulm/article/view/2589</self-uri><abstract><p>Целью работы явилось изучение обратимости бронхиальной обструкции у больных бронхиальной астмой с помощью метода спектральной туссофонобарографии, позволяющего проводить временночастотный анализ звуков кашля. В результате анализа были выделены три фазы в спектре звука кашля: 1 -я фаза — быстрое открытие гортани, 2 -я фаза — выход воздуха из легких, 3-я (непостоянная) фаза — закрытие гортани в конце кашля. Метод позволил выявить существенные различия спектральновременных параметров звуков кашля у больных бронхиальной астмой в результате проведения теста с β2-агонистом короткого действия (общая продолжительность кашля, продолжительность каждой фазы кашля, Fmax — частота максимальной энергии звука, F50% — частота, содержащая 50% энергии звука кашля, коэффициент q — отношение суммарной энергии низких и средних частот к энергии высоких частот). Таким образом, спектральная туссофонобарография является объективным методом оценки обратимости бронхиальной обструкции.</p></abstract><trans-abstract xml:lang="en"><p>The purpose of this study was to evaluate reversibility of the airway obstruction in asthma patients using a method of spectral tussophonobarography permitting to perform the frequency analysis of cough sounds. As a result the cough sound spectrum was divided into 3 phases: the 1st phase was due to quick opening of the larynx, the 2nd, more continuous phase was relevant to the air output out of the lungs, the 3rd, inconstant phase corresponded to the closure of the larynx at the end of the cough. The method showed significant changes of spectral and temporary parameters of the cough sounds before and after inhalation of a bronchodilator in asthma patients (common duration of cough, duration of each cough phase, frequency of maximal cough sound energy Fmax, frequency containing 50% of the cough sound energy F50%, q coefficient which is the ratio of total energy of low and middle frequencies to the energy of high frequencies). Thus, the spectral tussophonobarography is thought to be an objective method to evaluate the reversibility of the airway obstruction in asthma.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Любимов Г.А. Механика кашля. Физиология человека 1999; 25 (б): 81-88.</mixed-citation><mixed-citation xml:lang="en">Любимов Г.А. Механика кашля. Физиология человека 1999; 25 (б): 81-88.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Палеев И.Р. (ред.) Болезни органов дыхания: Руководство для врачей. М.: Медицина; 1989; т.4: 302-329.</mixed-citation><mixed-citation xml:lang="en">Палеев И.Р. (ред.) Болезни органов дыхания: Руководство для врачей. М.: Медицина; 1989; т.4: 302-329.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Почекутова И.А., Коренбаум В.И., Кулаков Ю.В. и др. О значении спектрально-временных параметров шума форсированного выдоха в оценке состояния бронхиальной проходимости. Физиология человека 2001; 27 (4): 61-65.</mixed-citation><mixed-citation xml:lang="en">Почекутова И.А., Коренбаум В.И., Кулаков Ю.В. и др. О значении спектрально-временных параметров шума форсированного выдоха в оценке состояния бронхиальной проходимости. Физиология человека 2001; 27 (4): 61-65.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Чучалин А.Г. (ред.) Глобальная стратегия лечения и профилактики бронхиальной астмы. М.: Атмосфера; 2002.</mixed-citation><mixed-citation xml:lang="en">Чучалин А.Г. (ред.) Глобальная стратегия лечения и профилактики бронхиальной астмы. М.: Атмосфера; 2002.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Fiz J.A., Jane R., Salvatella D. et al. Analysis of tracheal sounds during forced exhalation in asthma patients and normal subjects. Chest 1999; 116: 633-638.</mixed-citation><mixed-citation xml:lang="en">Fiz J.A., Jane R., Salvatella D. et al. Analysis of tracheal sounds during forced exhalation in asthma patients and normal subjects. Chest 1999; 116: 633-638.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Gross V., Ditm a r A., Penzel T. et al. The relationship between normal lung sounds, age, and gender. Am. J. Respir. Crit. Care Med. 2000; 162 (3): 905-909.</mixed-citation><mixed-citation xml:lang="en">Gross V., Ditm a r A., Penzel T. et al. The relationship between normal lung sounds, age, and gender. Am. J. Respir. Crit. Care Med. 2000; 162 (3): 905-909.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Olia P.M., Sestini P., Vagliasindi M . Acoustic parameters of voluntary cough in healthy non-smoking subjects. Respirology 2000; 5 (3): 271-275.</mixed-citation><mixed-citation xml:lang="en">Olia P.M., Sestini P., Vagliasindi M . Acoustic parameters of voluntary cough in healthy non-smoking subjects. Respirology 2000; 5 (3): 271-275.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Thiadens H.A., De Bock G.H., Van Houwelingen J.C. et al. Can peak expiratory flow measurements reliably identify the presence of airway obstruction and bronchodilator response as assessed by FEVj in primary care patients presenting with a persistent cough? Thorax 1999; 54: 1055-1060.</mixed-citation><mixed-citation xml:lang="en">Thiadens H.A., De Bock G.H., Van Houwelingen J.C. et al. Can peak expiratory flow measurements reliably identify the presence of airway obstruction and bronchodilator response as assessed by FEVj in primary care patients presenting with a persistent cough? Thorax 1999; 54: 1055-1060.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Thorpe C.W., Toop L.J., Dawson K.P. Towards a quantitative description of asthmatic cough sounds. Eur. Respir. J. 1992; 5 (6): 685-692.</mixed-citation><mixed-citation xml:lang="en">Thorpe C.W., Toop L.J., Dawson K.P. Towards a quantitative description of asthmatic cough sounds. Eur. Respir. J. 1992; 5 (6): 685-692.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
