pulmoПульмонологияPULMONOLOGIYA0869-01892541-9617Scientific and Practical Journal “PULMONOLOGIYA” LLCpulmo-2528Research ArticleОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯORIGINAL STUDIESИсследование вариативности сердечного ритма во время приступов бронхиальной астмыMonitoring autonomic activity in asthmaБеляловФ. И.BelyalovF. I.

Кафедра факультетской терапии 

ЛесинаН. С.LesinaN. S.

Кафедра факультетской терапии 

Иркутский государственный медицинский университетRussian Federation200419082021024649Copyright © Белялов Ф.И., Лесина Н.С., 20212021Белялов Ф.И., Лесина Н.С.Belyalov F.I., Lesina N.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.pulmonology.ru/pulm/article/view/2528

У 19 пациентов с бронхиальной астмой проводилось холтеровское мониторирование Э К Г со спектральным анализом сердечного ритма в 5-минутных интервалах за 2 ч до начала приступов астмы и в течение 1 ч после окончания. Всего проанализировано 49 приступов астмы.. В 27 % случаев перед приступом астмы наблюдалось повышение высокочастотной составляющей спектра мощности в диапазоне 0,15-0,40 Гц, что свидетельствует о возрастании парасимпатической активности. В оставшихся 73 % приступов существенных изменений высокочастотной и низкочастотной (0,05-0,15 Гц) составляющих спектра мощности не выявлено. Отмечено повышение низкочастотной  составляющей перед окончанием приступа в 37 % случаев, что более типично для ночных эпизодов и приступов с предшествующим повышением высокочастотной составляющей.

The spectral analysis of the heart rate variability was performed to assess the autonomic nervous system activity associated with 49 asthma attacks in 19 asthma patients. The 24-h Holter ECG recordings during 5-min intervals for 2 hours before to 1 hour after each asthma attack were analyzed using the fast Fourier analysis. There were no changes in low and high frequency bands in 73 % of the cases. The high frequency band (0.15-0.40 Hz) reflecting the parasympathetic activity increased 10 to 40 min before the asthma attacks in 27 % of the cases. The low frequency band (0.05-0.15 Hz) reflecting sympathetic activity increased before the asthma attacks finishing in 37 % of the cases that was typically for the nighttime symptoms and the attacks with the previous increase of the parasympathetic activity.

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The authors declare that there are no conflicts of interest present.