pulmoПульмонологияPULMONOLOGIYA0869-01892541-9617Scientific and Practical Journal “PULMONOLOGIYA” LLC10.18093/0869-0189-2021-31-6-808-815pulmo-2335Research ArticleОБЗОРЫREVIEWПатофизиология дыхания при ожиренииRespiratory pathophysiology in obesityhttps://orcid.org/0000-0001-8737-4264СергееваВ. А.SergeevaVictoria A.

Сергеева Виктория Алексеевна - кандидат медицинских наук, доцент кафедры терапии с курсами кардиологии, функциональной диагностики и геронтологии.

410012, Саратов, ул. Большая Казачья, 112; тел.: (8452) 51-15-34

Candidate of Medicine, assistant professor of the department of Therapy with Courses of Cardiology, Functional Diagnostics and Geriatrics.

Bolshaya Kazachia ul. 112, Saratov, 410012: tel.: (8452) 51-15-34

viktoriasergeeva@mail.ruФедеральное государственное бюджетное образовательное учреждение высшего образования Саратовский государственный медицинский университет имени В.И. Разумовского Минздрава РоссииРоссияFederal State Educational Institution of High Education Saratov State Medical University named after V.I. Razumovsky, Healthcare Ministry of Russian FederationRussian Federation202116122021316808815Copyright © Сергеева В.А., 20212021Сергеева В.А.Sergeeva V.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.pulmonology.ru/pulm/article/view/2335

Ожирение в современном мире — важнейшая медико-социальная проблема, при которой требуется междисциплинарный подход ряда медицинских специалистов. Многие заболевания дыхательной системы (ДС) обусловлены именно развитием ожирения.

Целью обзора явился анализ данных научных источников открытого доступа электронных библиотек PubMed и eLibrary за последние 15 лет о нарушениях функции внешнего дыхания (ФВД) у пациентов с ожирением.

Методы

Методы. Проведена сравнительная оценка и систематизация полученных результатов научных работ по приведенной теме. Выделены механические воздействия избыточной массы тела на дыхательную систему, приведены современные представления о клеточных и гуморальных влияниях жировой ткани на развитие патологии органов дыхания.

Заключение

Заключение. Получены убедительные данные о наличии многофакторного негативного влияния избыточной массы тела на аппарат дыхания, однако при развитии нарушений ФВД требуется дальнейшее изучение некоторых аспектов роли ожирения. Понимание патогенетических механизмов влияния ожирения на ДС необходимо для выработки дальнейшей стратегии ведения таких пациентов.

In the modern world, obesity is the most important medical and social problem that requires an interdisciplinary approach. Many diseases of the respiratory system are caused by obesity.

Aim

Aim. The review analyzes scientific sources on respiratory disorders in patients with obesity from the open-access electronic libraries PubMed and eLibrary published in the last 15 years.

Methods

Methods. A comparative systematical assessment of the results of these studies was carried out. The mechanical effects of excess body weight on the respiratory apparatus have been singled out. The current views about cellular and humoral effects of adipose tissue on the development of respiratory pathology have been given.

Conclusion

Conclusion. The analysis results present evidence of the multifactorial negative influence of excessive body weight on the respiratory system. Some aspects of the role of obesity in the development of respiratory disorders require further study. Understanding the pathogenic mechanisms behind the influence of obesity on the respiratory apparatus is essential for developing the patient management strategy.

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The authors declare that there are no conflicts of interest present.