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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pulmo</journal-id><journal-title-group><journal-title xml:lang="ru">Пульмонология</journal-title><trans-title-group xml:lang="en"><trans-title>PULMONOLOGIYA</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-0189</issn><issn pub-type="epub">2541-9617</issn><publisher><publisher-name>Scientific and Practical Journal “PULMONOLOGIYA” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18093/0869-0189-2020-30-6-831-841</article-id><article-id custom-type="elpub" pub-id-type="custom">pulmo-2219</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Полостные формы торакального саркоидоза (обзор литературы, клинико-рентгенологические наблюдения)</article-title><trans-title-group xml:lang="en"><trans-title>Cavity forms of thoracic sarcoidosis (literature review, clinical and radiological observations)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Леншин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lenshin</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Леншин Анатолий Васильевич — доктор медицинских наук, профессор, ведущий научный сотрудник лаборатории функциональных методов исследования дыхательной системы.</p><p>675000, Благовещенск, ул. Калинина, 22; тел.: (914) 558-19-37</p></bio><bio xml:lang="en"><p>Anatoliy V. Lenshin - Doctor of Medicine, Professor, Leading Researcher, Laboratory of Functional Research of Respiratory System.</p><p>Ul. Kalinina 22, Blagoveshchensk, 675000; tel.: (914) 558-19-37</p></bio><email xlink:type="simple">lenshin42@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ильин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Il'in</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ильин Андрей Валерьевич — кандидат медицинских наук, старший научный сотрудник лаборатории молекулярных и трансляционных исследований.</p></bio><bio xml:lang="en"><p>Andrey V. Il'in - Candidate of Medicine, Senior Researcher, Laboratory of Molecular and Translational Research.</p><p>Ul. Kalinina 22, Blagoveshchensk, 675000; tel.: (914) 561-69-52</p></bio><email xlink:type="simple">alero82@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Перельман</surname><given-names>Ю. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Perelman</surname><given-names>Yu. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Перельман Юлий Михайлович — доктор медицинских наук, профессор, член-корр. Российской академии наук, руководитель лаборатории функциональных методов исследования дыхательной системы.</p><p>675000, Благовещенск, ул. Калинина, 22; тел.: (4162) 77-28-01</p></bio><bio xml:lang="en"><p>Yuliy M. Perelman - Doctor of Medicine, Professor, Corresponding Member of Russian Academy of Sciences, Head of Laboratory of Functional Investigations of Respiratory System.</p><p>Ul. Kalinina 22, Blagoveshchensk, 675000; tel.: (4162) 77-28-01</p></bio><email xlink:type="simple">jperelman@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное научное учреждение Дальневосточный научный центр физиологии и патологии дыхания</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Far Eastern Research Center of Physiology and Respiratory Pathology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2020</year></pub-date><volume>30</volume><issue>6</issue><fpage>831</fpage><lpage>841</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Леншин А.В., Ильин А.В., Перельман Ю.М., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Леншин А.В., Ильин А.В., Перельман Ю.М.</copyright-holder><copyright-holder xml:lang="en">Lenshin A.V., Il'in A.V., Perelman Y.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.pulmonology.ru/pulm/article/view/2219">https://journal.pulmonology.ru/pulm/article/view/2219</self-uri><abstract><p>Полостные формы саркоидоза, при которых требуется дифференциальная диагностика с другими заболеваниями, проявляющимися рентгенологическими паттернами полости, полисегментарными узелковыми образованиями, гилюсной и медиастинальной лимфаденопатией, встречаются крайне редко. Проанализированы данные мировой литературы (1973-2018) по изучаемой проблеме, представлены результаты собственных клинико-рентгенологических наблюдений пациентов (n = 490) с различными формами саркоидоза. Полостные формы саркоидоза выявлены в 31 (6,3 %) случае - фиброзно-кистозные варианты при саркоидозе IV стадии (n = 8); саркоидоз на фоне кистозной гипоплазии (n = 7); объединенные формы первично-полостного саркоидоза и некротического саркоидного гранулематоза - у 6 (1,2 %) больных; сочетание саркоидоза и фиброзно-кавернозного туберкулеза (n = 5); саркоидоз с паттерном «обратный знак гало» (n = 5). Представлены примеры собственных клинико-рентгенологических наблюдений. Оптимизированы современные методы мультиспиральной компьютерной томографии, продемонстрированы возможности базовых программ постпроцессинговой обработки изображений, при использовании которых существенно повышаются чувствительность и специфичность томографического исследования.</p></abstract><trans-abstract xml:lang="en"><p>Cavity forms of sarcoidosis, which require differential diagnosis with other diseases, manifested by X-ray cavity patterns, polysegmental nodular formations, hilus and mediastinal lymphadenopathy, are extremely rare. The data of the world literature (1973 - 2018) on the studied problem are analyzed, the results of our own clinical and radiological observations of patients (n = 490) with various forms of sarcoidosis are presented. Cavity forms of sarcoidosis were detected in 31 (6.3%) cases — fibrocystic variants in stage IV sarcoidosis (n = 8); sarcoidosis on the background of cystic hypoplasia (n = 7); combined forms of primary cavity sarcoidosis and necrotic sarcoid granulomatosis in 6 (1.2%) patients; a combination of sarcoidosis and fibro-cavernous tuberculosis (n = 5); sarcoidosis with the pattern “reverse halo sign” (n = 5). Examples of our own clinical and radiological observations are presented. The modern methods of multispiral computed tomography have been optimized, the capabilities of the basic post-processing image processing programs have been demonstrated, the use of which significantly increases the sensitivity and specificity of tomographic research.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>полостные формы саркоидоза</kwd><kwd>первично-полостной саркоидоз</kwd><kwd>некротизирующий саркоидный гранулематоз</kwd><kwd>мульти-спиральная компьютерная томография</kwd><kwd>постпроцессинговая обработка изображений</kwd></kwd-group><kwd-group xml:lang="en"><kwd>abdominal forms of sarcoidosis</kwd><kwd>primary cavity sarcoidosis</kwd><kwd>necrotizing sarcoid granulomatosis</kwd><kwd>multispiral computed tomography</kwd><kwd>postprocessing image processing</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Визель А.А., ред. Саркоидоз: от гипотезы к практике. 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