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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pulmo</journal-id><journal-title-group><journal-title xml:lang="ru">Пульмонология</journal-title><trans-title-group xml:lang="en"><trans-title>PULMONOLOGIYA</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-0189</issn><issn pub-type="epub">2541-9617</issn><publisher><publisher-name>Scientific and Practical Journal “PULMONOLOGIYA” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18093/0869-0189-2005-0-3-69-75</article-id><article-id custom-type="elpub" pub-id-type="custom">pulmo-2074</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Диагностическая оценка функционального состояния трахеи у больных ХОБЛ</article-title><trans-title-group xml:lang="en"><trans-title>Functional evaluation of trachea in patients with COPD</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Марченков</surname><given-names>Я. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Marchenkov</surname><given-names>Ya. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пашкова</surname><given-names>Т. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Pashkova</surname><given-names>T. L.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чучалин</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Chuchalin</surname><given-names>A. G.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синицын</surname><given-names>В. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Sinitsin</surname><given-names>V. E.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>НИИ пульмонологии МЗ и СР РФ</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2005</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2005</year></pub-date><volume>0</volume><issue>3</issue><fpage>69</fpage><lpage>75</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Марченков Я.В., Пашкова Т.Л., Чучалин А.Г., Синицын В.Е., 2005</copyright-statement><copyright-year>2005</copyright-year><copyright-holder xml:lang="ru">Марченков Я.В., Пашкова Т.Л., Чучалин А.Г., Синицын В.Е.</copyright-holder><copyright-holder xml:lang="en">Marchenkov Y.V., Pashkova T.L., Chuchalin A.G., Sinitsin V.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.pulmonology.ru/pulm/article/view/2074">https://journal.pulmonology.ru/pulm/article/view/2074</self-uri><abstract><p>Хронический кашель, характерный для хронической обструктивной болезни легких (ХОБЛ), способен воздействовать на крупные верхние дыхательные пути. В этой связи актуально оценить состояние крупных дыхательных путей у пациентов с ХОБЛ и создать диагностическую программу для оценки их динамической патологии. Целью данного исследования являлась оценка диагностической эффективности различных методов диагностики динамических изменений трахеи у пациентов с ХОБЛ. В исследовании принимали участие 55 пациентов, из числа которых были отобраны по критериям включения 30 пациентов, разделенных на 2 группы на основании фибробронхоскопии. 1-я группа — 20 пациентов, имеющих признаки динамических изменений трахеи (ФБС): возраст — 60,9 ± 7,9 лет, 14 женщин и 6 мужчин, ИМТ — 28,2 ± 4,3 кг / м2, ХОБЛ IIA (GOLD), курение — 35,4 ± 5,2 пачко-лет. 2-я группа — 10 пациентов без динамических изменений трахеи (ФБС): возраст 55,2 ± 4,8 лет, 2 женщины и 8 мужчин, ИМТ — 26,8 ± 2,6 кг / м2, ХОБЛ IIA (GOLD), курение — 28,2 ± 3,4 пачко-лет. Пациенты проходили клиническое обследование, исследование кривой "поток–объем", бодиплетизмографию, импульсную осциллометрию, рентгенографию трахеи, фибробронхоскопию, электронно-лучевую томографию грудной клетки. В результате исследования было выявлено, что среди функциональных параметров наибольшую чувствительность имеет импульсная осциллометрия (85 %); электронно-лучевая томография обладает большей чувствительностью (90 %) по сравнению с рентгенографией трахеи (65 %) в выявлении динамической нестабильности трахеи у пациентов с ХОБЛ.</p></abstract><trans-abstract xml:lang="en"><p>Severe cough associated with COPD can induce dynamic instability of trachea. It is important to investigate large airways in COPD patients and to create diagnostic program for evaluation of this dynamic changes. Aim: to investigate sensitivity and specificity of different methods for detection of dynamic tracheal instability in COPD patients. Of fifty five patients involved in this study 30 ones were selected according to inclusion criteria. They were divided into 2 groups: 20 COPD stage 2 patients with dynamic tracheal instability detected by fiberoptic bronchoscopy (the 1-st group; 14 females, 6 males; the mean age, 60.9 ± 7.9 yrs; BMI, 28.2 ± 4.3 kg / m2; the smoking history, 35.4 ± 5.2 pack-year) and 10 COPD stage 2 patients without dynamic tracheal instability according to fiberoptic bronchoscopy findings (the 2nd group; 2 females and 8 males; the mean age, 55.2 ± 4.8 yrs; BMI, 26.8 ± 2.6 kg/m2; the smoking history, 28.2 ± 3.4 pack-year). Clinical examination, flow-volume curve, body plethysmography, impulse oscillometry, X-ray examination of trachea, fiberoptic bronchoscopy, and electron-beam tomography were used in our work. As a result, the most sensitive functional method was impulse oscillometry (Se = 85 %). Electron-beam tomography is more sensitive (Se = 90 %) than X-ray examination of trachea (Se = 65 %) while diagnosing dynamic tracheal instability in the COPD patients.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Овчаренко С.И. Хронические обструктивные болезни легких: современный взгляд на проблему. Врач 2001; 11: 3–7.</mixed-citation><mixed-citation xml:lang="en">Овчаренко С.И. Хронические обструктивные болезни легких: современный взгляд на проблему. Врач 2001; 11: 3–7.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Чучалин А.Г. Болезни курящего человека. Тер. арх. 1998; 3: 5–13.</mixed-citation><mixed-citation xml:lang="en">Чучалин А.Г. Болезни курящего человека. 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