pulmoПульмонологияPULMONOLOGIYA0869-01892541-9617Scientific and Practical Journal “PULMONOLOGIYA” LLC10.18093/0869-0189-2008-0-6-53-58pulmo-1874Research ArticleОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯORIGINAL STUDIESЭтиология фатальной внебольничной пневмонии у взрослыхEtiology of fatal community-acquired pneumonia in adultsИванчикН. В.IvanchikN. V.

Смоленск

КозловС. Н.KozlovS. N.

Смоленск

РачинаС. А.RachinaS. A.

Смоленск

КречиковаО. И.KrechikovaO. I.

Смоленск

ГОУ ВПО "Смоленская государственная медицинская академия"Russian Federation200828122008065358Copyright © Иванчик Н.В., Козлов С.Н., Рачина С.А., Кречикова О.И., 20082008Иванчик Н.В., Козлов С.Н., Рачина С.А., Кречикова О.И.Ivanchik N.V., Kozlov S.N., Rachina S.A., Krechikova O.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.pulmonology.ru/pulm/article/view/1874

Изучена структура возбудителей фатальной внебольничной пневмонии (ВП) у 63 взрослых пациентов в городах Смоленске и Ярцеве (Смоленская обл.). Гистологически подтвержденная пневмония имела место у 57 (90,5 %) пациентов. Материалом для исследования служил аутопсийный материал, полученный у пациентов, умерших от ВП. Бактериальная этиология ВП была установлена в 91,2 % случаев при гистологически подтвержденной пневмонии, при этом монокультура выделена в 75,0 %, микробные ассоциации – в 25,0 % случаев. Преобладающими возбудителями ВП были K. pneumoniae, S. aureus, S. pneumoniae и H. influenzae (31,4; 28,6; 12,9 и 11,4 % от всех выделенных штаммов соответственно). Важным фактором, определяющим структуру возбудителей и неблагоприятный исход заболевания, являлось наличие и характер сопутствующей патологии (алкоголизм, хронические заболевания сердечно-сосудистой и бронхолегочной системы).

Pathogens of fatal community-acquired pneumonia have been studied in 63 adult patients from Smolensk city and Yartsevo town of Smolensk region using autopsy material. Pneumonia was confirmed during histological exanimation in 57 (90.5 %) of the patients. Bacterial pathogens were identified in 91.2 % of the confirmed pneumonias, among them one type of pathogens was yielded in 75% and bacterial associations were identified in 25 % of the cases. The most prevalent pathogens were K. pneumoniae, S. aureus, S. pneumoniae and H. influenzae (31.4, 28.6, 12.9 and 11.4 % of all the identified strains, respectively). Comorbidity (alcohol abuse, chronic heart disease, chronic respiratory disease) was an important factor predetermining pathogen spectrum and poor outcome of the disease.

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The authors declare that there are no conflicts of interest present.