pulmoПульмонологияPULMONOLOGIYA0869-01892541-9617Scientific and Practical Journal “PULMONOLOGIYA” LLC10.18093/0869-0189-2010-3-46-52pulmo-1646Research ArticleСтатьиРеспираторная инфекция и роль сывороточных биомаркеров при обострении атопической бронхиальной астмыХаптхаеваГ. Э.noemail@neicon.ruЧучалинА. Г.noemail@neicon.ruПустоваловА. А.noemail@neicon.ruЗыковК. А.noemail@neicon.ruКолгановаН. А.noemail@neicon.ruФГУ "НИИ пульмонологии ФМБА России"Russian FederationООО "Независимая лаборатория "ИНВИТРО"Russian FederationЛаборатория пульмонологии Московского государственного медико-стоматологического университетаRussian FederationРоссийский государственный медицинский университет им. Н.А.ПироговаRussian Federation201028062010034652Copyright © Хаптхаева Г.Э., Чучалин А.Г., Пустовалов А.А., Зыков К.А., Колганова Н.А., 20102010Хаптхаева Г.Э., Чучалин А.Г., Пустовалов А.А., Зыков К.А., Колганова Н.А.Хаптхаева Г.Э., Чучалин А.Г., Пустовалов А.А., Зыков К.А., Колганова Н.А.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.pulmonology.ru/pulm/article/view/1646

К обострению бронхиальной астмы (БА) могут привести различные триггеры, в т. ч. респираторная инфекция. Целью настоящего исследования явилось изучение значимости сывороточных биомаркеров у пациентов с частыми обострениями атопической БА на фоне респираторной инфекции. Был обследован 31 человек - 4 мужчины и 27 женщин (средний возраст - 50,4 ± 13,5 лет). У больных с обострением атопической БА на фоне респираторной инфекции в результате комплексной микробиологической оценки было выявлено, что причиной обострения являлись вирусная (29,0 %), бактериальная (45,2 %) инфекция и ассоциации микроорганизмов (25,8 %). Уровень С-реактивного белка достоверно повышался у больных с бактериальной инфекцией, в то время как уровень интерферона-ƒ был достоверно снижен у пациентов с вирусной инфекцией, что свидетельствовало о диагностической значимости в этиологии обострения болезни. При сравнении сывороточных уровней данных цитокинов в исследуемых группах больных статистически значимой разницы не обнаружено.

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The authors declare that there are no conflicts of interest present.