pulmoПульмонологияPULMONOLOGIYA0869-01892541-9617Scientific and Practical Journal “PULMONOLOGIYA” LLC10.18093/0869-0189-2006-5-82-96pulmo-1498Research ArticleСтатьиЛегочная гиперинфляция у больных хронической
обструктивной болезнью легкихАвдеевС.Н.noemail@neicon.ru200628102006058296Copyright © Авдеев
С., 20062006Авдеев
С.Авдеев
С.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.pulmonology.ru/pulm/article/view/1498ReferencesGlobal Initiative for Chronic Obstructive Lung Diseases (GOLD). Global strategy for diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI / WHO workshop report. Publication Number 2701, April 2001: 1-100. Updated 2005. GOLD website (www.goldcopd.com).Global Initiative for Chronic Obstructive Lung Diseases (GOLD). Global strategy for diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI / WHO workshop report. Publication Number 2701, April 2001: 1-100. Updated 2005. GOLD website (www.goldcopd.com).ZuWallack R. Clinical interpretation of health-related quality of life outcomes in chronic obstructive pulmonary disease. Eur. Respir. Rev. 2002; 12 (83): 65-66.ZuWallack R. Clinical interpretation of health-related quality of life outcomes in chronic obstructive pulmonary disease. Eur. Respir. Rev. 2002; 12 (83): 65-66.O'Donnell D.E. Hyperinflation, dyspnea, and exercise intolerance in chronic obstructive pulmonary disease. Proc. Am. Thorac. Soc. 2006; 3: 180-184.O'Donnell D.E. Hyperinflation, dyspnea, and exercise intolerance in chronic obstructive pulmonary disease. Proc. Am. Thorac. Soc. 2006; 3: 180-184.Wolkove N., Dajczman E., Colacone A. et al. The relationship between pulmonary function and dyspnea in obstructive lung disease. Chest 1989; 96: 1247-1251.Wolkove N., Dajczman E., Colacone A. et al. The relationship between pulmonary function and dyspnea in obstructive lung disease. Chest 1989; 96: 1247-1251.Hay J.G., Stone P., Carter J. et al. Bronchodilator reversibility, exercise performance and breathlessness in stable chronic obstructive pulmonary disease. Eur. Respir. J. 1992; 5: 659-664.Hay J.G., Stone P., Carter J. et al. Bronchodilator reversibility, exercise performance and breathlessness in stable chronic obstructive pulmonary disease. Eur. Respir. J. 1992; 5: 659-664.Belman M.J., Botnick W.C., Shin J.W. Inhaled bronchodilators reduce dynamic hyperinflation during exercise in patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 1996; 153: 967-975.Belman M.J., Botnick W.C., Shin J.W. Inhaled bronchodilators reduce dynamic hyperinflation during exercise in patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 1996; 153: 967-975.O'Donnell D.E., Lam M., Webb K.A. Spirometric correlates of improvement in exercise performance after anticholinergic therapy in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 1999; 160: 542-549.O'Donnell D.E., Lam M., Webb K.A. Spirometric correlates of improvement in exercise performance after anticholinergic therapy in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 1999; 160: 542-549.Черняк А.В., Авдеев С.Н., Пашкова Т.Л., Айсанов З.Р. Бронходилатационный тест у больных с хронической обструктивной болезнью легких. Пульмонология 2003; 1: 50-56.Черняк А.В., Авдеев С.Н., Пашкова Т.Л., Айсанов З.Р. Бронходилатационный тест у больных с хронической обструктивной болезнью легких. Пульмонология 2003; 1: 50-56.Stokes W. A treatise on the diagnosis and treatment of diseases of the chest. Part 1. Diseases of the lung and windpipe. London: The New Sydenham Society; 1837. 168-169. www.medcyclopaedia.comStokes W. A treatise on the diagnosis and treatment of diseases of the chest. Part 1. Diseases of the lung and windpipe. London: The New Sydenham Society; 1837. 168-169. www.medcyclopaedia.comO'Donnell D.E. Introduction. Proc. Am. Thorac. Soc. 2006; 3: 175.O'Donnell D.E. Introduction. Proc. Am. Thorac. Soc. 2006; 3: 175.Dixon W.E., Brodie T.G. Contributions to the physiology of the lungs. 1. The bronchial muscles, their innervation, and the action of drugs upon them. J. Physiol. 1903; 29:97-173.Dixon W.E., Brodie T.G. Contributions to the physiology of the lungs. 1. The bronchial muscles, their innervation, and the action of drugs upon them. J. Physiol. 1903; 29:97-173.Comroe J.H. The lung: clinical physiology and pulmonary function tests (based on the 1954 Beaumont lecture). Chicago, Illinois: Year Book Medical Publishers; 1955.Comroe J.H. The lung: clinical physiology and pulmonary function tests (based on the 1954 Beaumont lecture). Chicago, Illinois: Year Book Medical Publishers; 1955.Вотчал Б.Е. Эмфизема легких. В кн. Молчанов Н.С. (ред.). Болезни органов дыхания. М.: Медицина; 1964. 247-282.Вотчал Б.Е. Эмфизема легких. В кн. Молчанов Н.С. (ред.). Болезни органов дыхания. М.: Медицина; 1964. 247-282.Potter W.A., Olafsson S., Hyatt R.E. Ventilatory mechanics and expiratory flow limitation during exercise in patients with obstructive lung disease. J. Clin. Invest. 1971; 50: 910-919.Potter W.A., Olafsson S., Hyatt R.E. Ventilatory mechanics and expiratory flow limitation during exercise in patients with obstructive lung disease. J. Clin. Invest. 1971; 50: 910-919.Macklem P.T. Hyperinflation. Am. Rev. Respir. Dis. 1984; 129: 1-2.Macklem P.T. Hyperinflation. Am. Rev. Respir. Dis. 1984; 129: 1-2.O'Donnell D.E., Webb K.A. Exertional breathlessness in patients with chronic airflow limitation. The role of lung hyperinflation. Am. Rev. Respir. Dis. 1993; 148: 1351-1357.O'Donnell D.E., Webb K.A. Exertional breathlessness in patients with chronic airflow limitation. The role of lung hyperinflation. Am. Rev. Respir. Dis. 1993; 148: 1351-1357.Calverley P.M.A., Koulouris N.G. Flow limitation and dynamic hyperinflation: key concepts in modern respiratory physiology. Eur. Respir. J. 2005; 25:186-199.Calverley P.M.A., Koulouris N.G. Flow limitation and dynamic hyperinflation: key concepts in modern respiratory physiology. Eur. Respir. J. 2005; 25:186-199.www.medcyclopaedia.comwww.medcyclopaedia.comGibson G.J. Pulmonary hyperinflation a clinical overview. Eur. Respir. J. 1996; 9: 2640-2649.Gibson G.J. Pulmonary hyperinflation a clinical overview. Eur. Respir. J. 1996; 9: 2640-2649.Ferguson G. Why does the lung hyperinflate? Proc. Am. Thorac. Soc. 2006; 3: 176-179.Ferguson G. Why does the lung hyperinflate? Proc. Am. Thorac. Soc. 2006; 3: 176-179.Milic-Emili J. Dynamic pulmonary hyperinflation and intrinsic PEEP: consequences and management in patients with chronic obstructive pulmonary disease. Recenti. Progr. Med. 1990; 81: 733-737.Milic-Emili J. Dynamic pulmonary hyperinflation and intrinsic PEEP: consequences and management in patients with chronic obstructive pulmonary disease. Recenti. Progr. Med. 1990; 81: 733-737.Hyatt R.E. The interrelationship of pressure, flow and volume during various respiratory maneuvers in normal and emphysematous patients. Am. Rev. Respir. Dis. 1961; 83: 676-683.Hyatt R.E. The interrelationship of pressure, flow and volume during various respiratory maneuvers in normal and emphysematous patients. Am. Rev. Respir. Dis. 1961; 83: 676-683.Similowski T., Yan S., Gauthier A.P. et al. Contractile properties of the human diaphragm during chronic hyperinflation. N. Engl. J. Med. 1991; 325: 917-923.Similowski T., Yan S., Gauthier A.P. et al. Contractile properties of the human diaphragm during chronic hyperinflation. N. Engl. J. Med. 1991; 325: 917-923.O'Donnell D.E., Bain D.J., Webb K.A. Factors contributing to relief of exertional breathlessness during hyperoxia in chronic airflow limitation. Am. J. Respir. Crit. Care Med. 1997; 155: 530-535.O'Donnell D.E., Bain D.J., Webb K.A. Factors contributing to relief of exertional breathlessness during hyperoxia in chronic airflow limitation. Am. J. Respir. Crit. Care Med. 1997; 155: 530-535.O'Donnell D.E., Lam M., Webb K.A. Spirometric correlates of improvement in exercise performance after anticholinergic therapy in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 1999; 160: 542-549.O'Donnell D.E., Lam M., Webb K.A. Spirometric correlates of improvement in exercise performance after anticholinergic therapy in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 1999; 160: 542-549.Авдеев С.Н., Чучалин А.Г. Дыхательная недостаточность при хронической обструктивной болезни легких. В кн.: Чучалин А.Г. (ред.). Хронические обструктивные болезни легких. М.: ЗАО "Издво "БИНОМ"; СПб.: Невский диалект; 1998. 249-275.Авдеев С.Н., Чучалин А.Г. Дыхательная недостаточность при хронической обструктивной болезни легких. В кн.: Чучалин А.Г. (ред.). Хронические обструктивные болезни легких. М.: ЗАО "Издво "БИНОМ"; СПб.: Невский диалект; 1998. 249-275.Авдеев С.Н. Роль легочной гиперинфляции в патогенезе ХОБЛ. Эффективность поддерживающей терапии в уменьшении легочной гиперинфляции. Пульмонология 2004; 6: 101-110.Авдеев С.Н. Роль легочной гиперинфляции в патогенезе ХОБЛ. Эффективность поддерживающей терапии в уменьшении легочной гиперинфляции. Пульмонология 2004; 6: 101-110.Авдеев С.Н. Легочная гиперинфляция у больных ХОБЛ. Consilium Medicum 2006; 8 (3): 75-80.Авдеев С.Н. Легочная гиперинфляция у больных ХОБЛ. Consilium Medicum 2006; 8 (3): 75-80.Murariu C., Ghezzo H., Milic-Emili J., Gautier H. Exercise limitation in obstructive lung disease. Chest 1998; 114: 965-968.Murariu C., Ghezzo H., Milic-Emili J., Gautier H. Exercise limitation in obstructive lung disease. Chest 1998; 114: 965-968.Marin J.M., Carrizo S.J., Gascon M. et al. Inspiratory capacity, dynamic hyperinflation, breathlessness and exercise performance during the 6-minute-walk test in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 2001; 163: 1395-1399.Marin J.M., Carrizo S.J., Gascon M. et al. Inspiratory capacity, dynamic hyperinflation, breathlessness and exercise performance during the 6-minute-walk test in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 2001; 163: 1395-1399.Casanova C., Cote C., de Torres J.P. et al. The inspiratory to total lung capacity ratio predicts mortality in patients with COPD. Am. J. Respir. Crit. Care Med. 2005; 171: 591-597.Casanova C., Cote C., de Torres J.P. et al. The inspiratory to total lung capacity ratio predicts mortality in patients with COPD. Am. J. Respir. Crit. Care Med. 2005; 171: 591-597.Kilburn K.H., Asmundsson T. Anteroposterior chest diameter in emphysema. Arch. Intern. Med. 1969; 123: 379-382.Kilburn K.H., Asmundsson T. Anteroposterior chest diameter in emphysema. Arch. Intern. Med. 1969; 123: 379-382.Gilmartin J.J., Gibson G.J. Abnormalities of chest wall motion in patients with chronic airflow obstruction. Thorax 1984; 39: 264-271.Gilmartin J.J., Gibson G.J. Abnormalities of chest wall motion in patients with chronic airflow obstruction. Thorax 1984; 39: 264-271.Hoover C.F. The diagnostic significance of inspiratory movements of the costal margins. Am. J. Med. Sci. 1920; 159: 633-646.Hoover C.F. The diagnostic significance of inspiratory movements of the costal margins. Am. J. Med. Sci. 1920; 159: 633-646.Garcia-Pachon E. Paradoxical movement of the lateral ribmargin (Hoover sign) for detecting obstructive airway disease. Chest 2002; 122: 651-655.Garcia-Pachon E. Paradoxical movement of the lateral ribmargin (Hoover sign) for detecting obstructive airway disease. Chest 2002; 122: 651-655.Capria M.E., D' Negri C., De Vito E.L. Relationship between Hoover sign, functional and variables, and curvature radius in patients with obstructive pulmonary disease. Medicina (B. Aires) 2003; 63: 369-376.Capria M.E., D' Negri C., De Vito E.L. Relationship between Hoover sign, functional and variables, and curvature radius in patients with obstructive pulmonary disease. Medicina (B. Aires) 2003; 63: 369-376.Cassart M., Pettiaux N., Gevenois P.A. et al. Effect of chronic hyperinflation on diaphragm length and surface area. Am. J. Respir. Crit. Care. Med. 1997; 156: 504-508.Cassart M., Pettiaux N., Gevenois P.A. et al. Effect of chronic hyperinflation on diaphragm length and surface area. Am. J. Respir. Crit. Care. Med. 1997; 156: 504-508.Decramer M. Hyperinflation and respiratory muscle interaction. Eur. Respir. J. 1997; 10: 934-941.Decramer M. Hyperinflation and respiratory muscle interaction. Eur. Respir. J. 1997; 10: 934-941.de Fregonezi G.A., Resqueti V.R., Guell Rous R. Pursed lip breathing. Arch. Bronconeumol. 2004; 40: 279-282.de Fregonezi G.A., Resqueti V.R., Guell Rous R. Pursed lip breathing. Arch. Bronconeumol. 2004; 40: 279-282.Bianchi R., Gigliotti F., Romagnoli I. et al. Chest wall kinematics and breathlessness during pursed-lip breathing in patients with COPD. Chest 2004; 125: 459-465.Bianchi R., Gigliotti F., Romagnoli I. et al. Chest wall kinematics and breathlessness during pursed-lip breathing in patients with COPD. Chest 2004; 125: 459-465.Mueller R.E., Petty T.L., Filley G.F. Ventilation and arterial blood gas changes induced by pursed lips breathing. J. Appl. Physiol. 1970; 28: 784-789.Mueller R.E., Petty T.L., Filley G.F. Ventilation and arterial blood gas changes induced by pursed lips breathing. J. Appl. Physiol. 1970; 28: 784-789.Breslin E.H. The pattern of respiratory muscle recruitment during pursed-lips breathing. Chest 1992; 101: 75-78.Breslin E.H. The pattern of respiratory muscle recruitment during pursed-lips breathing. Chest 1992; 101: 75-78.Spahija J.A., Grassino A. Effects of pursed-lips breathing and expiratory resistive loading in healthy subjects. J. Appl. Physiol. 1996; 80: 1772-1784.Spahija J.A., Grassino A. Effects of pursed-lips breathing and expiratory resistive loading in healthy subjects. J. Appl. Physiol. 1996; 80: 1772-1784.Campbell E.J. Respiratory failure: simple bedside tests of lung function. Proc. Roy. Soc. Med. 1962; 55: 566-569.Campbell E.J. Respiratory failure: simple bedside tests of lung function. Proc. Roy. Soc. Med. 1962; 55: 566-569.Campbell E.J. Physical signs of diffuse airways obstruction and lung distention. Thorax 1969; 24: 1-3.Campbell E.J. Physical signs of diffuse airways obstruction and lung distention. Thorax 1969; 24: 1-3.Maitre B., Similowski T., Derenne J.-P. Physical examination of the adult patient with respiratory diseases: inspection and palpation. Eur. Respir. J. 1995; 8: 1584-1593.Maitre B., Similowski T., Derenne J.-P. Physical examination of the adult patient with respiratory diseases: inspection and palpation. Eur. Respir. J. 1995; 8: 1584-1593.Stubbing D.G., Mathur P.N., Roberts R.S., Campbell E.J.M. Some physical signs in patients with chronic airflow obstruction. Am. Rev. Respir. Dis. 1982; 125: 549-552.Stubbing D.G., Mathur P.N., Roberts R.S., Campbell E.J.M. Some physical signs in patients with chronic airflow obstruction. Am. Rev. Respir. Dis. 1982; 125: 549-552.Straus S.E., McAlister F.A., Sackett D.L. et al. The accuracy of patient history, wheezing, and laryngeal measurements in diagnosing of obstructive airway diseases. J. A. M. A. 2000; 283: 1853-1857.Straus S.E., McAlister F.A., Sackett D.L. et al. The accuracy of patient history, wheezing, and laryngeal measurements in diagnosing of obstructive airway diseases. J. A. M. A. 2000; 283: 1853-1857.Burki N.K., Krumpelman J.L. Correlation of pulmonary function with the chest roentgenogram in chronic airways obstruction. Am. Rev. Respir. Dis. 1980; 121: 217-223.Burki N.K., Krumpelman J.L. Correlation of pulmonary function with the chest roentgenogram in chronic airways obstruction. Am. Rev. Respir. Dis. 1980; 121: 217-223.Nicklaus T.M., Stowell D.W., Christiansen W.R. et al. The accuracy of the roentgenologic diagnosis of chronic pulmonary emphysema. Am. Rev. Respir. Dis. 1966; 93: 889-899.Nicklaus T.M., Stowell D.W., Christiansen W.R. et al. The accuracy of the roentgenologic diagnosis of chronic pulmonary emphysema. Am. Rev. Respir. Dis. 1966; 93: 889-899.Pratt P.C. Role of conventional chest radiography in diagnosis and exclusion of emphysema. Am. J. Med. 1987; 82: 998-1006.Pratt P.C. Role of conventional chest radiography in diagnosis and exclusion of emphysema. Am. J. Med. 1987; 82: 998-1006.Reich S.B., Weinshelbaum A., Iwee J. Correlation of radiographic measurements and pulmonary function tests in chronic obstructive pulmonary disease. Am. J. Roentgenol. 1985; 144: 695-699.Reich S.B., Weinshelbaum A., Iwee J. Correlation of radiographic measurements and pulmonary function tests in chronic obstructive pulmonary disease. Am. J. Roentgenol. 1985; 144: 695-699.Thurlbeck W.M., Simon G. Radiographic appearance of the chest in emphysema. Am. J. Roentgenol. 1978; 130: 429-440.Thurlbeck W.M., Simon G. Radiographic appearance of the chest in emphysema. Am. J. Roentgenol. 1978; 130: 429-440.Sutinen S., Christoforidis A.J., Klugh G.A. et al. Roentgenologic criteria for the recognition of non-symptomatic pulmonary emphysema: Correlation between roentgenologic findings and pulmonary pathology. Am. Rev. Respir. Dis. 1965; 91: 69-76.Sutinen S., Christoforidis A.J., Klugh G.A. et al. Roentgenologic criteria for the recognition of non-symptomatic pulmonary emphysema: Correlation between roentgenologic findings and pulmonary pathology. Am. Rev. Respir. Dis. 1965; 91: 69-76.Pratt P.C., Klugh G.A. A method for the determination of total lung capacity from posteroanterior and lateral chest roentgenograms. Am. Rev. Respir. Dis. 1967; 96: 548-552.Pratt P.C., Klugh G.A. A method for the determination of total lung capacity from posteroanterior and lateral chest roentgenograms. Am. Rev. Respir. Dis. 1967; 96: 548-552.Rodenstein D.O., Sopwith T., Denison D.M., Stanescu D.C. Reevaluation of the radiographic method for measurement of total lung capacity. Bull. Eur. Physiopathol. Respir. 1985; 21: 521-525.Rodenstein D.O., Sopwith T., Denison D.M., Stanescu D.C. Reevaluation of the radiographic method for measurement of total lung capacity. Bull. Eur. Physiopathol. Respir. 1985; 21: 521-525.Rothpearl A., Varma A.O., Goodman K. Radiographic measures of hyperinflation in clinical emphysema. Discrimination of patients from controls and relationship to physiologic and mechanical lung function. Chest 1988; 94: 907-913.Rothpearl A., Varma A.O., Goodman K. Radiographic measures of hyperinflation in clinical emphysema. Discrimination of patients from controls and relationship to physiologic and mechanical lung function. Chest 1988; 94: 907-913.Spence D.P.S, Kelley Y.J., Ahmed J. et al. Critical evaluation of computerized X-ray planimetry for the measurement of lung volumes. Thorax 1995; 50: 383-386.Spence D.P.S, Kelley Y.J., Ahmed J. et al. Critical evaluation of computerized X-ray planimetry for the measurement of lung volumes. Thorax 1995; 50: 383-386.Brown M.S., McNittGray M.F., Goldin J.G. et al. Automated measurement of single and total lung volume from CT. J. Comput. Assist. Tomogr. 1999; 23: 632-640.Brown M.S., McNittGray M.F., Goldin J.G. et al. Automated measurement of single and total lung volume from CT. J. Comput. Assist. Tomogr. 1999; 23: 632-640.Davy H. Researches, chemical and philosophical, chiefly concerning nitrous oxide, or dephlogisticated nitrous air, and its respiration. London: Johnson; 1800.Davy H. Researches, chemical and philosophical, chiefly concerning nitrous oxide, or dephlogisticated nitrous air, and its respiration. London: Johnson; 1800.Brown R., Enright P., Leith D. Multiple-breath helium dilution measurements of lung volumes in adults. Eur. Respir. J. 1998; 11: 246-255.Brown R., Enright P., Leith D. Multiple-breath helium dilution measurements of lung volumes in adults. Eur. Respir. J. 1998; 11: 246-255.Cala S.J., Kenyon C.M., Ferrigno G. et al. Chest wall and lung volume estimation by optical reflectance motion analysis. J. Appl. Physiol. 1996; 81: 2680-2689.Cala S.J., Kenyon C.M., Ferrigno G. et al. Chest wall and lung volume estimation by optical reflectance motion analysis. J. Appl. Physiol. 1996; 81: 2680-2689.Stanescu D.C., Rodenstein D., Cauberghs M. et al. Failure of body plethysmography in bronchial asthma. J. Appl. Physiol. 1982; 52: 939-948.Stanescu D.C., Rodenstein D., Cauberghs M. et al. Failure of body plethysmography in bronchial asthma. J. Appl. Physiol. 1982; 52: 939-948.Fairshter R.D. Airway hysteresis in normal subjects and individuals with chronic airflow obstruction. J. Appl. Physiol. 1985; 58: 1505-1510.Fairshter R.D. Airway hysteresis in normal subjects and individuals with chronic airflow obstruction. J. Appl. Physiol. 1985; 58: 1505-1510.Yang S., Kaminski D., Sliwinski P. Reliability of inspiratory capacity for estimating end expiratory lung volume changes during exercise in patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 1997; 156: 55-59.Yang S., Kaminski D., Sliwinski P. Reliability of inspiratory capacity for estimating end expiratory lung volume changes during exercise in patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 1997; 156: 55-59.Tantucci C., Duguet A., Similowski T. et al. Effect of salbutamol on dynamic hyperinflation in chronic obstructive pulmonary disease patients. Eur. Respir. J. 1998; 12: 799-804.Tantucci C., Duguet A., Similowski T. et al. Effect of salbutamol on dynamic hyperinflation in chronic obstructive pulmonary disease patients. Eur. Respir. J. 1998; 12: 799-804.Duranti R., Filippelli M., Bianchi R., et al. Inspiratory capacity and decrease in lung hyperinflation with albuterol in COPD. Chest 2002; 122: 2009-2014.Duranti R., Filippelli M., Bianchi R., et al. Inspiratory capacity and decrease in lung hyperinflation with albuterol in COPD. Chest 2002; 122: 2009-2014.Dolmage T.E., Goldstein R.S. Repeatability of inspiratory capacity during incremental exercise in patients with severe COPD. Chest 2002; 121: 708-714.Dolmage T.E., Goldstein R.S. Repeatability of inspiratory capacity during incremental exercise in patients with severe COPD. Chest 2002; 121: 708-714.Pellegrino R., Brusasco V. Lung hyperinflation and flow limitation in chronic airway obstruction. Eur. Respir. J. 1997; 10: 543-549.Pellegrino R., Brusasco V. Lung hyperinflation and flow limitation in chronic airway obstruction. Eur. Respir. J. 1997; 10: 543-549.Hadcroft J., Calverley P.M.A. Alternative methods for assessing bronchodilatator reversibility in chronic obstructive pulmonary disease. Thorax 2001; 56: 713-720.Hadcroft J., Calverley P.M.A. Alternative methods for assessing bronchodilatator reversibility in chronic obstructive pulmonary disease. Thorax 2001; 56: 713-720.Gelb A.F., Gutierrez C.A., Weisman I.M. et al. Simplified detection of dynamic hyperinflation. Chest 2004; 126; 1855-1860.Gelb A.F., Gutierrez C.A., Weisman I.M. et al. Simplified detection of dynamic hyperinflation. Chest 2004; 126; 1855-1860.Brantigan O., Mueller E. Surgical treatment of pulmonary emphysema. Am. Surg. 1957; 23: 789-804.Brantigan O., Mueller E. Surgical treatment of pulmonary emphysema. Am. Surg. 1957; 23: 789-804.Cooper J.D., Trulock E.P., Triantafillou A.N. et al. Bilateral pneumectomy (volume reduction) for chronic obstructive pulmonary disease. J. Thorac. Cardiovasc. Surg. 1995; 109: 106-116.Cooper J.D., Trulock E.P., Triantafillou A.N. et al. Bilateral pneumectomy (volume reduction) for chronic obstructive pulmonary disease. J. Thorac. Cardiovasc. Surg. 1995; 109: 106-116.Martinez F.J., Montes de Oca M., Whyte R.I. et al. Lung-volume reduction improves dyspnea, dynamic hyperinflation and respiratory muscle function. Am. J. Respir. Crit. Care Med. 1997; 155:1984-1990.Martinez F.J., Montes de Oca M., Whyte R.I. et al. Lung-volume reduction improves dyspnea, dynamic hyperinflation and respiratory muscle function. Am. J. Respir. Crit. Care Med. 1997; 155:1984-1990.National Emphysema Treatment Trial Research Group. A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema. N. Engl. J. Med. 2003; 348: 2059-2073.National Emphysema Treatment Trial Research Group. A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema. N. Engl. J. Med. 2003; 348: 2059-2073.Keller C.A., Ruppel G., Hibbett A. et al. Thoracoscopic lung volume reduction surgery reduces dyspnea and improves exercise capacity in patients with emphysema. Am. J. Respir. Crit. Care Med. 1997; 156: 60-67.Keller C.A., Ruppel G., Hibbett A. et al. Thoracoscopic lung volume reduction surgery reduces dyspnea and improves exercise capacity in patients with emphysema. Am. J. Respir. Crit. Care Med. 1997; 156: 60-67.Fujimoto T., Teschler H., Hillejan L. et al. Long-term results of lung volume reduction surgery. Europ. J. Cardiothorac. Surg. 2002; 21: 483-488.Fujimoto T., Teschler H., Hillejan L. et al. Long-term results of lung volume reduction surgery. Europ. J. Cardiothorac. Surg. 2002; 21: 483-488.Hopkinson N.S., Toma T.P., Hansell D. et al. Effect of bronchoscopic lung volume reduction on dynamic hyperinflation and exercise in emphysema. Am. J. Respir. Crit. Care Med. 2005; 171: 453-460.Hopkinson N.S., Toma T.P., Hansell D. et al. Effect of bronchoscopic lung volume reduction on dynamic hyperinflation and exercise in emphysema. Am. J. Respir. Crit. Care Med. 2005; 171: 453-460.Wan I.Y.P, Toma T.P., Geddes D.M. et al. Bronchoscopic lung volume reduction for end-stage emphysema: report on the first 98 patients. Chest 2006; 129: 518-526.Wan I.Y.P, Toma T.P., Geddes D.M. et al. Bronchoscopic lung volume reduction for end-stage emphysema: report on the first 98 patients. Chest 2006; 129: 518-526.Chrystyn H., Mulley B.A., Peak M.D. Dose response relation to oral theophylline in severe chronic obstructive airways disease. Brit. Med. J. 1988; 297:1506-1510.Chrystyn H., Mulley B.A., Peak M.D. Dose response relation to oral theophylline in severe chronic obstructive airways disease. Brit. Med. J. 1988; 297:1506-1510.Di Marco F., Milic-Emili J., Boveri B. et al. Effect of inhaled bronchodilators on inspiratory capacity and dyspnoea at rest in COPD. Eur. Respir. J. 2003; 21: 86-94.Di Marco F., Milic-Emili J., Boveri B. et al. Effect of inhaled bronchodilators on inspiratory capacity and dyspnoea at rest in COPD. Eur. Respir. J. 2003; 21: 86-94.Celli B., ZuWallack R., Wang S., Kesten S. Improvement in resting inspiratory capacity and hyperinflation with tiotropium in COPD patients with increased static lung volumes. Chest 2003; 124: 1743-1748.Celli B., ZuWallack R., Wang S., Kesten S. Improvement in resting inspiratory capacity and hyperinflation with tiotropium in COPD patients with increased static lung volumes. Chest 2003; 124: 1743-1748.O'Donnell D.E., Fluge T., Gerken F. et al. Effects of tiotropium on lung hyperinflation, dyspnoea and exercise tolerance in COPD. Eur. Respir. J. 2004. 23: 832-840.O'Donnell D.E., Fluge T., Gerken F. et al. Effects of tiotropium on lung hyperinflation, dyspnoea and exercise tolerance in COPD. Eur. Respir. J. 2004. 23: 832-840.O'Donnell D.E., Voduc N., Fitzpatrick M., Webb K.A. Effect of salmeterol on the ventilatory response to exercise in chronic obstructive pulmonary disease. Eur. Respir. J. 2004; 24: 86-94.O'Donnell D.E., Voduc N., Fitzpatrick M., Webb K.A. Effect of salmeterol on the ventilatory response to exercise in chronic obstructive pulmonary disease. Eur. Respir. J. 2004; 24: 86-94.van Noord S.A., Aumann J.L., Janssens E. et al. Effect of tiotropium with and without formoterol on airflow obstruction and resting hyperinflation in patients with COPD. Chest 2006; 129: 509-517.van Noord S.A., Aumann J.L., Janssens E. et al. Effect of tiotropium with and without formoterol on airflow obstruction and resting hyperinflation in patients with COPD. Chest 2006; 129: 509-517.Medical Research Council Working Party. Long term domiciliary oxygen therapy in chronic hypoxic cor pulmonale complicating chronic bronchitis and emphysema. Lancet 1981;1: 681-686.Medical Research Council Working Party. Long term domiciliary oxygen therapy in chronic hypoxic cor pulmonale complicating chronic bronchitis and emphysema. Lancet 1981;1: 681-686.Dean N.C., Brown J.K., Himelman R.B. et al. Oxygen may improve dyspnea and endurance in patients with chronic obstructive pulmonary disease and only mild hipoxemia. Am. Rev. Respir. Dis. 1992; 146: 941-945.Dean N.C., Brown J.K., Himelman R.B. et al. Oxygen may improve dyspnea and endurance in patients with chronic obstructive pulmonary disease and only mild hipoxemia. Am. Rev. Respir. Dis. 1992; 146: 941-945.Woodcock A.A., Gross E.R., Geddes D.M. Oxygen relieves breathlessness in "pink puffers". Lancet 1981; 1: 907-909.Woodcock A.A., Gross E.R., Geddes D.M. Oxygen relieves breathlessness in "pink puffers". Lancet 1981; 1: 907-909.Somfay A., Porszasz J., Lee S.M., Casaburi R. Dose-response effect of oxygen on hyperinflation and exercise endurance in nonhypoxaemic COPD patients. Eur. Respir. J. 2001; 18: 77-84.Somfay A., Porszasz J., Lee S.M., Casaburi R. Dose-response effect of oxygen on hyperinflation and exercise endurance in nonhypoxaemic COPD patients. Eur. Respir. J. 2001; 18: 77-84.Alvisi V., Mirkovic T., Nesme P. et al. Acute effects of hyperoxia on dyspnea in hypoxemia patients with chronic airway obstruction at rest. Chest 2003; 123: 1038-1046.Alvisi V., Mirkovic T., Nesme P. et al. Acute effects of hyperoxia on dyspnea in hypoxemia patients with chronic airway obstruction at rest. Chest 2003; 123: 1038-1046.Casaburi R., Porszasz J. Reduction of hyperinflation by pharmacologic and other interventions. Proc. Am. Thorac. Soc. 2006; 3: 185-189.Casaburi R., Porszasz J. Reduction of hyperinflation by pharmacologic and other interventions. Proc. Am. Thorac. Soc. 2006; 3: 185-189.Barach A.L. The use of helium in the treatment of asthma and obstructive lesions of the larynx and trachea. Ann. Intern. Med. 1935; 9: 739-765.Barach A.L. The use of helium in the treatment of asthma and obstructive lesions of the larynx and trachea. Ann. Intern. Med. 1935; 9: 739-765.Gluck E.H., Onorato D.J., Castriotta R. Helium-oxygen mixtures in intubated patients with status asthmaticus and respiratory acidosis. Chest 1990; 98: 693-698.Gluck E.H., Onorato D.J., Castriotta R. Helium-oxygen mixtures in intubated patients with status asthmaticus and respiratory acidosis. Chest 1990; 98: 693-698.Manthous C.A., Hall J.B., Melmed A., Caputo M.A. et al. Heliox improves pulsus paradoxus and peak expiratory flow in nonintubated patients with severe asthma. Am. J. Respir. Crit. Care. Med. 1995; 151: 310- 314.Manthous C.A., Hall J.B., Melmed A., Caputo M.A. et al. Heliox improves pulsus paradoxus and peak expiratory flow in nonintubated patients with severe asthma. Am. J. Respir. Crit. Care. Med. 1995; 151: 310- 314.Jolliet P., Tassaux D., Thouret J.M. et al. Beneficial effects of helium: oxygen vs. air:oxygen noninvasive pressure support in with decompensated chronic obstructive pulmonary disease. Crit. Care Med. 1999; 27: 2422-2429.Jolliet P., Tassaux D., Thouret J.M. et al. Beneficial effects of helium: oxygen vs. air:oxygen noninvasive pressure support in with decompensated chronic obstructive pulmonary disease. Crit. Care Med. 1999; 27: 2422-2429.Papamoschou D. Theoretical validation of the respiratory benefits of heliumoxygen mixtures. Respir. Physiol. 1995; l99: 183-90.Papamoschou D. Theoretical validation of the respiratory benefits of heliumoxygen mixtures. Respir. Physiol. 1995; l99: 183-90.Oelberg D.A., Kacmarek R.M., Pappagianopoulos P.P. et al. Ventilatory and cardiovascular responses to inspired HeO2 during exercise in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 1998; 158: 1876-1882.Oelberg D.A., Kacmarek R.M., Pappagianopoulos P.P. et al. Ventilatory and cardiovascular responses to inspired HeO2 during exercise in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 1998; 158: 1876-1882.Palange P., Valli G., Onorati P. et al. Effect of heliox on lung dynamic hyperinflation, dyspnea and exercise endurance capacity in COPD patients. J. Appl. Physiol. 2004; 97: 1637-1642.Palange P., Valli G., Onorati P. et al. Effect of heliox on lung dynamic hyperinflation, dyspnea and exercise endurance capacity in COPD patients. J. Appl. Physiol. 2004; 97: 1637-1642.Laude E.A., Duffy N.C., Baveystock C. et al. The effect of helium and oxygen on exercise performance in COPD: a randomised crossover trial. A. J. R. C. C. M. In Press 2006.Laude E.A., Duffy N.C., Baveystock C. et al. The effect of helium and oxygen on exercise performance in COPD: a randomised crossover trial. A. J. R. C. C. M. In Press 2006.Robert D., Gerald M., Leger P. et al. Ventilation mecanique a domicile des insuffisants respiratoires chroniques. Rev. Fr. Mal. Respir. 1983; 11: 923-936.Robert D., Gerald M., Leger P. et al. Ventilation mecanique a domicile des insuffisants respiratoires chroniques. Rev. Fr. Mal. Respir. 1983; 11: 923-936.Leger P., Muir J.F. Selection of patients for long-term nasal intermittent positive pressure ventilation: practical aspects. Eur. Respir. Monogr. 1998; 8: 328-347.Leger P., Muir J.F. Selection of patients for long-term nasal intermittent positive pressure ventilation: practical aspects. Eur. Respir. Monogr. 1998; 8: 328-347.Cuvelier A., Muir J.F. Noninvasive ventilation and obstructive lung disease. Eur. Respir. J. 2001; 17: 1271-1281.Cuvelier A., Muir J.F. Noninvasive ventilation and obstructive lung disease. Eur. Respir. J. 2001; 17: 1271-1281.Meecham Jones D.J., Paul E.A., Jones P.W., Wedzicha J.A. Nasal pressure support ventilation plus oxygen compared with oxygen therapy alone in hypercapnic COPD. Am. J. Respir. Rev. Crit. Care Med. 1995; 152: 538-544.Meecham Jones D.J., Paul E.A., Jones P.W., Wedzicha J.A. Nasal pressure support ventilation plus oxygen compared with oxygen therapy alone in hypercapnic COPD. Am. J. Respir. Rev. Crit. Care Med. 1995; 152: 538-544.Elliott M.W., Mulvey D.A., Moxham J. et al. Domiciliary nocturnal nasal intermittent positive pressure ventilation in COPD: mechanisms underlying changes in arterial blood gas tensions. Eur. Respir. J. 1991; 4: 1044-1052.Elliott M.W., Mulvey D.A., Moxham J. et al. Domiciliary nocturnal nasal intermittent positive pressure ventilation in COPD: mechanisms underlying changes in arterial blood gas tensions. Eur. Respir. J. 1991; 4: 1044-1052.Diaz O., Begin P., Torrealba. B. Effects of noninvasive ventilation on lung hyperinflation in stable hypercapnic COPD. Eur. Respir. J. 2002; 20: 1490-1498.Diaz O., Begin P., Torrealba. B. Effects of noninvasive ventilation on lung hyperinflation in stable hypercapnic COPD. Eur. Respir. J. 2002; 20: 1490-1498.Budweiser S., Heinemann F., Fischer W. et al. Long-term reduction of hyperinflation in stable COPD by noninvasive nocturnal home ventilation. Respir. Med. 2005; 99: 976-984.Budweiser S., Heinemann F., Fischer W. et al. Long-term reduction of hyperinflation in stable COPD by noninvasive nocturnal home ventilation. Respir. Med. 2005; 99: 976-984.Lacasse Y., Guyatt G.H., Goldstein R.S. The components of a respiratory rehabilitation program: a systematic overview. Chest 1997; 111: 1077-1088.Lacasse Y., Guyatt G.H., Goldstein R.S. The components of a respiratory rehabilitation program: a systematic overview. Chest 1997; 111: 1077-1088.Lacasse Y., Wong E., Guyatt G.H. et al. Meta-analysis of respiratory rehabilitation in chronic obstructive pulmonary diseases. Lancet 1996; 348: 1115-1119.Lacasse Y., Wong E., Guyatt G.H. et al. Meta-analysis of respiratory rehabilitation in chronic obstructive pulmonary diseases. Lancet 1996; 348: 1115-1119.Porszasz J., Emtner M., Goto S. et al. Exercise training decreases exercise-induced hyperinflation in patients with COPD. Chest 2005; 128: 2025-2034.Porszasz J., Emtner M., Goto S. et al. Exercise training decreases exercise-induced hyperinflation in patients with COPD. Chest 2005; 128: 2025-2034.
The authors declare that there are no conflicts of interest present.