<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pulmo</journal-id><journal-title-group><journal-title xml:lang="ru">Пульмонология</journal-title><trans-title-group xml:lang="en"><trans-title>PULMONOLOGIYA</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-0189</issn><issn pub-type="epub">2541-9617</issn><publisher><publisher-name>Scientific and Practical Journal “PULMONOLOGIYA” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18093/0869-0189-2006-3-62-69</article-id><article-id custom-type="elpub" pub-id-type="custom">pulmo-1454</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>"Жемчужное" зерно: история стрептомицина
От Ваксмана к Ваксману</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Камро-Мл.</surname><given-names>Дж.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email></contrib></contrib-group><pub-date pub-type="collection"><year>2006</year></pub-date><pub-date pub-type="epub"><day>28</day><month>06</month><year>2006</year></pub-date><volume>0</volume><issue>3</issue><fpage>62</fpage><lpage>69</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Камро-Мл.
                 Д., 2006</copyright-statement><copyright-year>2006</copyright-year><copyright-holder xml:lang="ru">Камро-Мл.
                 Д.</copyright-holder><copyright-holder xml:lang="en">Камро-Мл.
                 Д.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.pulmonology.ru/pulm/article/view/1454">https://journal.pulmonology.ru/pulm/article/view/1454</self-uri></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Waksman S.A. and Woodruff H.В. The soil as a source of microorganisms antagonistic to diseaseproducing bacteria. J. Bacteriol, 1940, 40, 581-600.</mixed-citation><mixed-citation xml:lang="en">Waksman S.A. and Woodruff H.В. The soil as a source of microorganisms antagonistic to diseaseproducing bacteria. J. Bacteriol, 1940, 40, 581-600.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Waksman S.A. The Antibiotic Era: A History of the antibiotics and of their role in the conquest of Infectious diseases and in other fields of human endeavor, the waksman foundation of japan, 1975.</mixed-citation><mixed-citation xml:lang="en">Waksman S.A. The Antibiotic Era: A History of the antibiotics and of their role in the conquest of Infectious diseases and in other fields of human endeavor, the waksman foundation of japan, 1975.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Waksman S.A. and Woodruff H.В. Bacteriostatic and bactericidal substances produced by soil actinomyces, Proc. Soc. Exp. Biol. Med., 1940, 45, 609-614.</mixed-citation><mixed-citation xml:lang="en">Waksman S.A. and Woodruff H.В. Bacteriostatic and bactericidal substances produced by soil actinomyces, Proc. Soc. Exp. Biol. Med., 1940, 45, 609-614.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Waksman S.A. and Woodruff H.В. Streptothricin, a new selective bacteriostatic and bactericidal agent, particularly active against gramnegative bacteria, Proc. Soc. Exp. Biol. Med., 1942, 49, 207-210.</mixed-citation><mixed-citation xml:lang="en">Waksman S.A. and Woodruff H.В. Streptothricin, a new selective bacteriostatic and bactericidal agent, particularly active against gramnegative bacteria, Proc. Soc. Exp. Biol. Med., 1942, 49, 207-210.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Schatz A., Bugie, E. and Waksman S.A. Streptomycin, a substance exhibiting antibiotic activity against grampositive and gramnegative bacteria, Proc. Soc. Exp. Biol. Med., 1944, 55, 66-69.</mixed-citation><mixed-citation xml:lang="en">Schatz A., Bugie, E. and Waksman S.A. Streptomycin, a substance exhibiting antibiotic activity against grampositive and gramnegative bacteria, Proc. Soc. Exp. Biol. Med., 1944, 55, 66-69.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Feldman W.H. and Hinshaw H.C. Effects of streptomycin on experimental tuberculosis in guinea pigs: A preliminary report, Proc Staff Meetings Mayo Clin., 1944, 19, 593-599.</mixed-citation><mixed-citation xml:lang="en">Feldman W.H. and Hinshaw H.C. Effects of streptomycin on experimental tuberculosis in guinea pigs: A preliminary report, Proc Staff Meetings Mayo Clin., 1944, 19, 593-599.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Hinshaw H.C. and Feldman W.H. Streptomycin in treatment of clinical tuberculosis: A preliminary report, Proc Staff Meetings Mayo Clin., 1945, 20, 313-318.</mixed-citation><mixed-citation xml:lang="en">Hinshaw H.C. and Feldman W.H. Streptomycin in treatment of clinical tuberculosis: A preliminary report, Proc Staff Meetings Mayo Clin., 1945, 20, 313-318.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Waksman S.A. and Curtis R. The actinomyces of the soil, Soil Sci, 1916, 1, 99-134.</mixed-citation><mixed-citation xml:lang="en">Waksman S.A. and Curtis R. The actinomyces of the soil, Soil Sci, 1916, 1, 99-134.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Waksman S.A.: Antagonistic relations of microorganisms, Bacteriol. Rev., 1941, 5-6, 231-291.</mixed-citation><mixed-citation xml:lang="en">Waksman S.A.: Antagonistic relations of microorganisms, Bacteriol. Rev., 1941, 5-6, 231-291.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Ehrlich P. and Hata S. Die Experimentelle Chemotherapie der Spirillosen, Berlin, Springer, 1910.</mixed-citation><mixed-citation xml:lang="en">Ehrlich P. and Hata S. Die Experimentelle Chemotherapie der Spirillosen, Berlin, Springer, 1910.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Wells H.G. The chemotherapy of tuberculosis, Yale J. Biol. Med., 1931-2, 4, 611-626.</mixed-citation><mixed-citation xml:lang="en">Wells H.G. The chemotherapy of tuberculosis, Yale J. Biol. Med., 1931-2, 4, 611-626.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Waksman S.A., and Starkey R.L. The Soil and the Microbe: An Introduction to the Study of the Microscopic Population of the Soil and Its Role in Soil Processes and Plant Growth, John Wiley, London, 1931.</mixed-citation><mixed-citation xml:lang="en">Waksman S.A., and Starkey R.L. The Soil and the Microbe: An Introduction to the Study of the Microscopic Population of the Soil and Its Role in Soil Processes and Plant Growth, John Wiley, London, 1931.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Waksman S.A. and Davison W.C. Enzymes: Properties, Distribution, Methods and Applications, Williams and Wilkins, Baltimore, 1926.</mixed-citation><mixed-citation xml:lang="en">Waksman S.A. and Davison W.C. Enzymes: Properties, Distribution, Methods and Applications, Williams and Wilkins, Baltimore, 1926.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Waksman S.A. Principles of Soil Microbiology, Williams and Wilkins, Baltimore, 1st ed., 1927; 2nd ed, 1932.</mixed-citation><mixed-citation xml:lang="en">Waksman S.A. Principles of Soil Microbiology, Williams and Wilkins, Baltimore, 1st ed., 1927; 2nd ed, 1932.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Waksman S.A. Humus: Origin, Chemical Composition, and Importance in Nature, Williams and Wilkins, Baltimore, 1st ed., 1936; 2nd ed., 1938.</mixed-citation><mixed-citation xml:lang="en">Waksman S.A. Humus: Origin, Chemical Composition, and Importance in Nature, Williams and Wilkins, Baltimore, 1st ed., 1936; 2nd ed., 1938.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Avery О.Т. and Dubos R. The specific action of a bacterial enzyme on pneumococci of type III, Science, 1930, 72, 151-152.</mixed-citation><mixed-citation xml:lang="en">Avery О.Т. and Dubos R. The specific action of a bacterial enzyme on pneumococci of type III, Science, 1930, 72, 151-152.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Dubos R. and Avery О.Т. Decomposition of the capsular polysaccharide of pneumococcus type III by a bacterial enzyme, J. Exp. Med., 1931, 54, 51-71.</mixed-citation><mixed-citation xml:lang="en">Dubos R. and Avery О.Т. Decomposition of the capsular polysaccharide of pneumococcus type III by a bacterial enzyme, J. Exp. Med., 1931, 54, 51-71.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Bordley J. and Harvey A.M. Two Centuries of American Medicine, 1776-1976, W.B.Saunders, Philadelphia, 1976, p. 456.</mixed-citation><mixed-citation xml:lang="en">Bordley J. and Harvey A.M. Two Centuries of American Medicine, 1776-1976, W.B.Saunders, Philadelphia, 1976, p. 456.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Benison S. Rene Dubos and the capsular polysaccharide of pneumococcus. Bull Hist. Med., 1976, 50, 459-477.</mixed-citation><mixed-citation xml:lang="en">Benison S. Rene Dubos and the capsular polysaccharide of pneumococcus. Bull Hist. Med., 1976, 50, 459-477.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Dubos R.J. Studies on a bactericidal agent extracted from a soil bacillus. I. Preparation of the agent. Its activity in vitro, J. Exp. Med., 1939, 70, 1-10. II. Protective effect of the bactericidal agent against experimental pneumococcus infections in mice, J. Exp. Med., 1939, 70, 11-17.</mixed-citation><mixed-citation xml:lang="en">Dubos R.J. Studies on a bactericidal agent extracted from a soil bacillus. I. Preparation of the agent. Its activity in vitro, J. Exp. Med., 1939, 70, 1-10. II. Protective effect of the bactericidal agent against experimental pneumococcus infections in mice, J. Exp. Med., 1939, 70, 11-17.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Rhines C. The longevity of tubercle bacilli in sewage and streamwater. Am. Rev. Tuberc., 1935, 31, 493-497.</mixed-citation><mixed-citation xml:lang="en">Rhines C. The longevity of tubercle bacilli in sewage and streamwater. Am. Rev. Tuberc., 1935, 31, 493-497.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Rhines C. The persistence ofavian tubercle bacilli in soil and in association with soil microorganisms, J. Bacteriol, 1935, 29, 299-311.</mixed-citation><mixed-citation xml:lang="en">Rhines C. The persistence ofavian tubercle bacilli in soil and in association with soil microorganisms, J. Bacteriol, 1935, 29, 299-311.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Rhines C. The relationship of soil protozoa to tubercle bacilli, J. Bacteriol, 1935, 29, 369-381.</mixed-citation><mixed-citation xml:lang="en">Rhines C. The relationship of soil protozoa to tubercle bacilli, J. Bacteriol, 1935, 29, 369-381.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Waksman S.A. The Conquest of Tuberculosis, University of California Press, Berkeley, 1964.</mixed-citation><mixed-citation xml:lang="en">Waksman S.A. The Conquest of Tuberculosis, University of California Press, Berkeley, 1964.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Waksman S.A. Tenth anniversary of the discovery of streptomycin, the first chemotherapeutic agent found to be effective against tuberculosis in humans. Am. Rev. Tuberc, 1954, 70, 1-8.</mixed-citation><mixed-citation xml:lang="en">Waksman S.A. Tenth anniversary of the discovery of streptomycin, the first chemotherapeutic agent found to be effective against tuberculosis in humans. Am. Rev. Tuberc, 1954, 70, 1-8.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Waksman S.A. My Life with the Microbes, Simon and Schuster, New York, 1954.</mixed-citation><mixed-citation xml:lang="en">Waksman S.A. My Life with the Microbes, Simon and Schuster, New York, 1954.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Banting F.G., Best C.H., Collip J.В., Macleod J.R.R., Noble E.C. The effect of pancreatic extract (insulin) on normal rabbits. Am. J. Physiol.1922, 62, 162-176.</mixed-citation><mixed-citation xml:lang="en">Banting F.G., Best C.H., Collip J.В., Macleod J.R.R., Noble E.C. The effect of pancreatic extract (insulin) on normal rabbits. Am. J. Physiol.1922, 62, 162-176.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Kelner A. Studies on the genetics of antibiotic formation: The induction of antibioticforming mutants in actinomycetes, J. Bacteriol, 1949, 57, 73-92.</mixed-citation><mixed-citation xml:lang="en">Kelner A. Studies on the genetics of antibiotic formation: The induction of antibioticforming mutants in actinomycetes, J. Bacteriol, 1949, 57, 73-92.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Birath G. Introduction of paraaminosalicylic acid and streptomycin in the treatment of tuberculosis, Scand. J. Resp. Dis., 1969, 50, 204-209.</mixed-citation><mixed-citation xml:lang="en">Birath G. Introduction of paraaminosalicylic acid and streptomycin in the treatment of tuberculosis, Scand. J. Resp. Dis., 1969, 50, 204-209.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Jones D., Metzger H.J., Schatz A. and Waksman, S.A. Control of gramnegative bacteria in experimental animals by streptomycin. Science, 1944, 100, 103-105.</mixed-citation><mixed-citation xml:lang="en">Jones D., Metzger H.J., Schatz A. and Waksman, S.A. Control of gramnegative bacteria in experimental animals by streptomycin. Science, 1944, 100, 103-105.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Dowling H.F. Fighting Infection; Conquests of the Twentieth Century, Harvard University Press, Cambridge, 1977, p. 162.</mixed-citation><mixed-citation xml:lang="en">Dowling H.F. Fighting Infection; Conquests of the Twentieth Century, Harvard University Press, Cambridge, 1977, p. 162.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
