pulmoПульмонологияPULMONOLOGIYA0869-01892541-9617Scientific and Practical Journal “PULMONOLOGIYA” LLC10.18093/0869-0189-2019-29-4-468-476pulmo-1200Research ArticleОБЗОРЫREVIEWОстрые формы ишемической болезни сердца при обострении хронической обструктивной болезни легких: эпидемиология, диагностика и лечениеAcute exacerbation of COPD and comorbid cardiovascular diseasesАнаевЭ. Х.AnaevE. Kh.

Анаев Эльдар Хусеевич – доктор медицинских наук, профессор кафедры пульмонологии Федерального государственного бюджетного образовательного учреждения высшего образования «Российский национальный исследовательский медицинский университет имени Н.И.Пирогова» Министерства здравоохранения Российской Федерации, врач-пульмонолог Московского научно-клинического образовательного центра респираторной медицины Государственного бюджетного учреждения здравоохранения города Москвы «Городская клиническая больница имени Д.Д.Плетнева Департамента здравоохранения города Москвы»

117997, Москва, ул. Островитянова, 1, 

105077, Москва, ул. 11-я Парковая, 32

 

El'dar Kh. Anaev, Doctor of Medicine, Professor, Department of Pulmonology, N.I.Pirogov Federal Russian National Research Medical University, Healthcare Ministry of Russia; pulmonologist, Moscow Research and Clinical Teaching Center of Respiratory Medicine, D.D.Pletnev City Teaching Hospital, Moscow Healthcare Department

ul. Ostrovityanova 1, Moscow, 117997, 

ul. Odinnadtsataya Parkovaya 32, Moscow, 105077

el_anaev@hotmail.comГореликИ. Л.GorelikI. L.

Горелик Ирина Львовна – кандидат медицинских наук, врач отделения функциональной и ультразвуковой диагностики

105077, Москва, ул. 11-я Парковая, 32

Irina L. Gorelik, Candidate of Medicine, physician, Department of Functional and Ultrasound Diagnostics

ul. Odinnadtsataya Parkovaya 32, Moscow, 105077

gorelik.ira@yandex.ruФедеральное государственное бюджетное образовательное учреждение высшего образования «Российский национальный исследовательский медицинский университет имени Н.И.Пирогова» Министерства здравоохранения Российской Федерации; Государственное бюджетное учреждение здравоохранения города Москвы «Городская клиническая больница имени Д.Д.Плетнева Департамента здравоохранения города Москвы»РоссияN.I.Pirogov Federal Russian National Research Medical University, Healthcare Ministry of Russia; D.D.Pletnev City Teaching Hospital, Moscow Healthcare DepartmentRussian FederationГосударственное бюджетное учреждение здравоохранения города Москвы «Городская клиническая больница имени Д.Д.Плетнева Департамента здравоохранения города Москвы»РоссияD.D.Pletnev City Teaching Hospital, Moscow Healthcare DepartmentRussian Federation201924102019294468476Copyright © Анаев Э.Х., Горелик И.Л., 20192019Анаев Э.Х., Горелик И.Л.Anaev E.K., Gorelik I.L.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.pulmonology.ru/pulm/article/view/1200

Хроническая обструктивная болезнь легких (ХОБЛ) является одной из основных проблем здравоохранения в мире. ХОБЛ тесно связана с коморбидными сердечно-сосудистыми заболеваниями (ССЗ), утяжеляющими ХОБЛ и повышающими риск смерти. Частота и распространенность ССЗ пи ХОБЛ составляет около 64 %. Примерно у 30 % пациентов с ХОБЛ наступает летальный исход от сердечно-сосудистых осложнений (ССО). Последние данные свидетельствуют о повышенном риске острого ИМ при тяжелом обострении ХОБЛ. Риск развития ССО увеличивается при тахикардии, повышении окислительного стресса и системном воспалении. По данным ряда исследований, для ранней диагностики ССО могут быть полезны не только методы визуализации, но и электрокардиография, а также анализ крови на биомаркеры. Несмотря на доказанные преимущества, некоторые препараты, обладающие способностью изменить прогноз при сердечно-сосудистой патологии, в частности кардиоселективные β-адреноблокаторы, у больных ХОБЛ используются недостаточно. Данный обзор посвящен некоторым аспектам обострения ХОБЛ и риска ССЗ.

Chronic obstructive pulmonary disease (COPD) is a major public health problem worldwide. COPD is closely related to comorbid cardiovascular diseases, which contribute to the worsening of COPD and increased mortality. The frequency and prevalence of cardiovascular diseases in patients with COPD is about 64%. Approximately 30% of patients with COPD die from cardiovascular complications. Recent evidence suggests an increased risk of acute myocardial infarction in severe exacerbations of COPD. Tachycardia, increased oxidative stress and systemic inflammation in patients with COPD may contribute to an increased risk of developing cardiovascular complications. Several studies may be useful for early diagnosis, including electrocardiography, imaging methods, and biomarker blood tests. Some drugs that have changed the prognosis for cardiovascular disease, in particular, cardioselective beta-blockers, are underused in patients with COPD, despite proven benefits. This review focuses on some aspects of COPD exacerbation and the risk of cardiovascular disease.

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The authors declare that there are no conflicts of interest present.