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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pulmo</journal-id><journal-title-group><journal-title xml:lang="ru">Пульмонология</journal-title><trans-title-group xml:lang="en"><trans-title>PULMONOLOGIYA</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-0189</issn><issn pub-type="epub">2541-9617</issn><publisher><publisher-name>Scientific and Practical Journal “PULMONOLOGIYA” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18093/0869-0189-2019-29-2-207-215</article-id><article-id custom-type="elpub" pub-id-type="custom">pulmo-1147</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Современные данные о возможностях улучшения переносимости физической нагрузки и значении физической активности у больных с хронической обструктивной болезнью легких</article-title><trans-title-group xml:lang="en"><trans-title>Current data on improvement in physical tolerance and a role of physical activity in patients with chronic obstructive pulmonary disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Айсанов</surname><given-names>З. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Aisanov</surname><given-names>Zaurbek R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Айсанов Заурбек Рамазанович – д. м. н., профессор кафедры пульмонологии Федерального государственного бюджетного образовательного учреждения высшего образования «Российский национальный исследовательский медицинский университет имени Н.И.Пирогова» Министерства здравоохранения Российской Федерации; тел.: (495) 965-34-66;</p><p>117997, Москва, ул. Островитянова, 1;</p></bio><bio xml:lang="en"><p>Zaurbek R. Aisanov, Doctor of Medicine, Professor, Department of Pulmonology, N.I.Pirogov Federal Russian National Research Medical University, Healthcare Ministry of Russia; tel.: (495) 965-34-66</p><p>ul. Ostrovityanova 1, Moscow, 117997</p></bio><email xlink:type="simple">aisanov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белоцерковская</surname><given-names>Ю. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Belotserkovskaya</surname><given-names>Yuliya G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Белоцерковская Юлия Геннадьевна – к. м. н., доцент кафедры пульмонологии Федерального государственного бюджетного образовательного учреждения дополнительного профессионального образования «Российская медицинская академия непрерывного профессионального образования» Министерства здравоохранения Российской Федерации; тел.: (499) 728-83-69;</p><p>123995, Москва, ул. Баррикадная, 2, стр. 1</p></bio><bio xml:lang="en"><p>Yuliya G. Belotserkovskaya, Candidate of Medicine, Associate Professor, Department of Pulmonology, Russian Federal Academy of Continued Medical Education, Healthcare Ministry of Russia; tel.: (499) 728-83-69;</p><p>ul. Barrikadnaya 2/1, Moscow, 123995</p></bio><email xlink:type="simple">belo-yuliya@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Авдеев</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Avdeev</surname><given-names>Sergey N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Авдеев Сергей Николаевич – д. м. н., профессор, член-корр. Российской академии наук, заведующий кафедрой пульмонологии Федерального государственного автономного образовательного учреждения высшего образования «Первый Московский государственный медицинский университет имени И.М.Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский Университет); тел.: (495) 395-63-93;</p><p>119991, Москва, ул. Трубецкая, 8, стр. 2</p></bio><bio xml:lang="en"><p>Sergey N. Avdeev, Doctor of Medicine, Professor, Corresponding Member of Russian Academy of Sciences, Head of Department of Pulmonology, I.M.Sechenov First Moscow State Medical University, Healthcare Ministry of Russia (Sechenov University); tel.: (495) 395-63-93;</p><p>Trubetskaya ul. 8, build. 2, Moscow, 119991</p></bio><email xlink:type="simple">serg_avdeev@list.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белевский</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Belevskiy</surname><given-names>Andrey S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Белевский Андрей Станиславович – д. м. н., профессор, заведующий кафедрой пульмонологии Федерального государственного бюджетного образовательного учреждения высшего образования Российский национальный исследовательский медицинский университет имени Н.И.Пирогова Министерства здравоохранения Российской Федерации, президент Российского респираторного общества, главный внештатный специалист-пульмонолог Департамента здравоохранения Правительства Москвы; тел.: (495) 963-24-67;</p><p>117997, Москва, ул. Островитянова, 1</p></bio><bio xml:lang="en"><p>Andrey S. Belevskiy, Doctor of Medicine, Professor, Head of Department of Pulmonology, N.I.Pirogov Federal Russian State National Research Medical University, Healthcare Ministry of Russia; Chairmen of Russian Respiratory Society; Chief Pulmonologist of Moscow Healthcare Department; tel.: (495) 963-24-67;</p><p>ul. Ostrovityanova 1, Moscow, 117997</p></bio><email xlink:type="simple">pulmobas@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Российский национальный исследовательский медицинский университет имени Н.И.Пирогова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.I.Pirogov Federal Russian State National Research Medical University, Healthcare Ministry of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>едеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования «Российская медицинская академия непрерывного профессионального образования» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Federal Academy of Continued Medical Education, Healthcare Ministry of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Первый Московский государственный медицинский университет имени И.М.Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M.Sechenov First Moscow State Medical University (Sechenov University), Healthcare Ministry of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>01</day><month>07</month><year>2019</year></pub-date><volume>29</volume><issue>2</issue><fpage>207</fpage><lpage>215</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Айсанов З.Р., Белоцерковская Ю.Г., Авдеев С.Н., Белевский А.С., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Айсанов З.Р., Белоцерковская Ю.Г., Авдеев С.Н., Белевский А.С.</copyright-holder><copyright-holder xml:lang="en">Aisanov Z.R., Belotserkovskaya Y.G., Avdeev S.N., Belevskiy A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.pulmonology.ru/pulm/article/view/1147">https://journal.pulmonology.ru/pulm/article/view/1147</self-uri><abstract><p>При определении тяжести течения и прогноза у пациентов с хронической обструктивной болезнью легких (ХОБЛ) важная роль принадлежит такому фактору, как физическая активность (ФА). По данным современных исследований продемонстрировано, что снижение ФА ассоциировано с увеличением частоты обострений ХОБЛ, летальности и снижением качества жизни больных ХОБЛ. Поскольку основу заболевания составляет ограничение воздушного потока, то при уменьшении легочной гиперинфляции при помощи двойных бронходилататоров переносимость физической нагрузки (ФН) у пациентов с ХОБЛ может улучшиться. Согласно существующим данным о применении комбинации тиотропий / олодатерол убедительно доказано, что при использовании двойных бронходилататоров у больных ХОБЛ увеличиваются время переносимости ФН и период до появления одышки во время ФН. Вместе с тем требуются дальнейшие исследования в области реабилитации и использования ФН в терапии пациентов с ХОБЛ.</p></abstract><trans-abstract xml:lang="en"><p>Physical activity plays an important prognostic role in patients with chronic obstructive pulmonary disease (COPD). According to published data, decreased physical activity is associated with higher frequency of COPD exacerbations, higher mortality, and lower quality of life in COPD patients. As the airflow limitation is an underlying mechanism of COPD, double bronchodilators can reduce lung hyperinflation and improve exercise tolerance in patients with COPD. According to the robust evidence on the efficacy of tiotropium/olodaterol combination, double bronchodilators can increase exercise duration and time before dyspnea occurrence on exertion. However, further studies are needed in the field of rehabilitation and a role of physical activity in the management of patients with COPD.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая обструктивная болезнь легких</kwd><kwd>бронходилататоры длительного действия</kwd><kwd>физическая активность</kwd><kwd>переносимость физической нагрузки</kwd><kwd>тиотропий</kwd><kwd>тиотропий / олодатерол</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic obstructive pulmonary disease</kwd><kwd>long-acting bronchodilators</kwd><kwd>physical activity</kwd><kwd>exercise tolerance</kwd><kwd>tiotropium</kwd><kwd>tiotropium/olodaterol</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">World Health Organization. Noncommunicable diseases: key facts. 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