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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pulmo</journal-id><journal-title-group><journal-title xml:lang="ru">Пульмонология</journal-title><trans-title-group xml:lang="en"><trans-title>PULMONOLOGIYA</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-0189</issn><issn pub-type="epub">2541-9617</issn><publisher><publisher-name>Scientific and Practical Journal “PULMONOLOGIYA” LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.18093/0869-0189-2019-29-1-71-86</article-id><article-id custom-type="elpub" pub-id-type="custom">pulmo-1111</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Современные подходы к консервативной терапии взрослых пациентов с бронхоэктазами</article-title><trans-title-group xml:lang="en"><trans-title>Current approaches to pharmacological treatment of adult patients with bronchiectasis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чикина</surname><given-names>С. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Chikina</surname><given-names>S. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чикина Светлана Юрьевна – кандидат медицинских наук, ассистент кафедры пульмонологии.</p><p>119991, Москва, ул. Трубецкая, 8, стр. 2; тел.: (916) 116-04-03.</p></bio><bio xml:lang="en"><p>Svetlana Yu. Chikina - Candidate of Medicine; Assistant Lecturer.</p><p>Trubetskaya ul. 8, build 2, Moscow, 119991; tel.: (916) 116-04-03.</p></bio><email xlink:type="simple">svch@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Авдеев</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Avdeev</surname><given-names>S. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Авдеев Сергей Николаевич – доктор медицинских наук, член-корреспондент Российской академии наук, профессор, заведующий кафедрой пульмонологии Первого МГМУ имени И.М.Сеченова МЗ РФ, руководитель клинического отдела НИИ пульмонологии Федерального медико-биологического агентства.</p><p>119991, Москва, ул. Трубецкая, 8, стр. 2; 115682, Москва, Ореховый бульвар, 28; тел.: (495) 708-35-76.</p></bio><bio xml:lang="en"><p>Sergey N. Avdeev - Doctor of Medicine, Professor, Corresponding Member of Russian Academy of Sciences, Head of Department of Pulmonology, I.M.Sechenov First Moscow State Medical University, Healthcare Ministry of Russia (Sechenov University); Deputy Director for Science, Federal Pulmonology Research Institute, Federal Medical and Biological Agency of Russia; Chief Pulmonologist, Healthcare Ministry of Russia.</p><p>Trubetskaya ul. 8, build 2, Moscow, 119991; Orekhovyy bul'var 28, Moscow, 115682; tel.: (495) 708-35-76.</p></bio><email xlink:type="simple">serg_avdeev@list.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет имени И.М.Сеченова Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M.Sechenov First Moscow State Medical University, Healthcare Ministry of Russia (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет имени И.М.Сеченова Министерства здравоохранения Российской Федерации; Научно-исследовательский институт пульмонологии Федерального медико-биологического агентства</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M.Sechenov First Moscow State Medical University, Healthcare Ministry of Russia (Sechenov University); Federal Pulmonology Research Institute, Federal Medical and Biological Agency of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>22</day><month>04</month><year>2019</year></pub-date><volume>29</volume><issue>1</issue><fpage>71</fpage><lpage>86</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чикина С.Ю., Авдеев С.Н., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Чикина С.Ю., Авдеев С.Н.</copyright-holder><copyright-holder xml:lang="en">Chikina S.Y., Avdeev S.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.pulmonology.ru/pulm/article/view/1111">https://journal.pulmonology.ru/pulm/article/view/1111</self-uri><abstract><p>Бронхоэктазы (БЭ) – достаточно распространенное хроническое бронхолегочное заболевание, однако в настоящее время в мире четкие клинические рекомендации по лечению этого заболевания не разработаны, а опубликованная информация не позволяет однозначно оценить эффективность используемых сегодня методов консервативной терапии БЭ. В то же время основной целью ведения пациентов с БЭ является предотвращение обострений, уменьшение выраженности симптомов, улучшение качества жизни и замедление прогрессирования заболевания. В данном обзоре проанализирована доступная информация об эффективности и целесообразности применения отдельных групп лекарственных препаратов у пациентов с БЭ, а также немедикаментозных методов улучшения бронхиального клиренса.</p></abstract><trans-abstract xml:lang="en"><p>Bronchiectasis is a chronic airway disease. Currently, no evidence-based recommendations on pharmacological treatment of bronchiectasis have been developed in the world. Published data is not sufficient to clear assessment of efficacy of pharmacological and non-pharmacological treatment for those patients. The main goals of treatment of bronchiectasis are to prevent exacerbations, to control symptoms, to improve quality of life, and to slow down progression of the disease. This article is a review of published data on efficacy and a role of selected pharmacological therapies of bronchiectasis and bronchial clearance techniques in adult patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>бронхоэктазы</kwd><kwd>немедикаментозные методы улучшения бронхиального клиренса</kwd><kwd>муколитичесикие препараты</kwd><kwd>бронходилататоры</kwd><kwd>ингаляционные антибактериальные препараты</kwd><kwd>макролиды</kwd></kwd-group><kwd-group xml:lang="en"><kwd>bronchiectasis</kwd><kwd>bronchial clearance</kwd><kwd>mucolytics</kwd><kwd>bronchodilators</kwd><kwd>inhaled antibiotics</kwd><kwd>macrolides</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bilton D., Jones A.L. Bronchiectasis: epidemiology and causes. In: Floto R.A., Haworth C.S., eds. Bronchiectasis. Eur. Respir. Monograph. 2011; 52: 239–247. 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