pulmoПульмонологияPULMONOLOGIYA0869-01892541-9617Scientific and Practical Journal “PULMONOLOGIYA” LLC10.18093/0869-0189-2012-0-1-40-46pulmo-10Research ArticleОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯORIGINAL STUDIESАвдеевС. Н.AvdeevS. N.

д. м. н., проф., руководитель клинического отдела

105077, Москва, ул. 11-я Парковая, 32, корп. 4. Тел. / факс: (495) 465-52-64.

serg-avdeev@list.ruБаймакановаГ. Е.BaymkanovaG. E.

к. м. н., старший научный сотрудник лаборатории интенсивной терапии и дыхательной недостаточности 

105077, Москва, ул. 11-я Парковая, 32, корп. 4. Тел. / факс: (495) 465-74-15.

gulsara.bai@mail.ruЗубаироваП. А.ZubairovaP. A.

к. м. н., старший научный сотрудник лаборатории интенсивной терапии и дыхательной недостаточности 

105077, Москва, ул. 11-я Парковая, 32, корп. 4. Тел. / факс: (495) 465-74-15.

zubairova@mail.ruКарчевскаяН. А.KarchevskayaN. A.

научный сотрудник лаборатории интенсивной терапии и дыхательной недостаточности

105077, Москва, ул. 11-я Парковая, 32, корп. 4. Тел. / факс: (495) 465-74-15.

karchevskaia@mail.ruФГУ "НИИ пульмонологии" ФМБА РоссииRussian Federation201228022012014046Copyright © Авдеев С.Н., Баймаканова Г.Е., Зубаирова П.А., Карчевская Н.А., 20122012Авдеев С.Н., Баймаканова Г.Е., Зубаирова П.А., Карчевская Н.А.Avdeev S.N., Baymkanova G.E., Zubairova P.A., Karchevskaya N.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.pulmonology.ru/pulm/article/view/10ReferencesGlobal Initiative for Chronic Obstructive Lung Disease (GOLD). Global strategy for diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI / WHO workshop report. Last updated 2011. www.goldcopd.orgGlobal Initiative for Chronic Obstructive Lung Disease (GOLD). Global strategy for diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI / WHO workshop report. Last updated 2011. www.goldcopd.orgStanford R.H., Shen Y., McLaughlin T. Cost of chronic obstructive pulmonary disease in the emergency department and hospital: an analysis of administrative data from 218 US hospitals. Treat. Respir. Med. 2006; 5: 343–349.Stanford R.H., Shen Y., McLaughlin T. Cost of chronic obstructive pulmonary disease in the emergency department and hospital: an analysis of administrative data from 218 US hospitals. Treat. Respir. Med. 2006; 5: 343–349.O'Donnell D.E., Parker C.M. COPD exacerbations: Pathophysiology. Thorax 2006; 61; 354–361.O'Donnell D.E., Parker C.M. COPD exacerbations: Pathophysiology. Thorax 2006; 61; 354–361.Donaldson G.C., Seemungal T.A.R., Bhowmik A., Wedzicha J.A. Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease. Thorax 2002; 57: 847–852.Donaldson G.C., Seemungal T.A.R., Bhowmik A., Wedzicha J.A. Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease. Thorax 2002; 57: 847–852.Seemungal T.A.R., Donaldson G.C., Paul E.A. et al. Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 1998; 151: 1418–1422.Seemungal T.A.R., Donaldson G.C., Paul E.A. et al. Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 1998; 151: 1418–1422.Miravitlles M., Murio C., Guerrero T. et al. Pharmacoeconomic evaluation of acute exacerbations of chronic bronchitis and COPD. Chest 2002; 121: 1449–1455.Miravitlles M., Murio C., Guerrero T. et al. Pharmacoeconomic evaluation of acute exacerbations of chronic bronchitis and COPD. Chest 2002; 121: 1449–1455.Celli B.R., Barnes P.J. Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease. Eur. Respir. J. 2007; 29: 1224–1238.Celli B.R., Barnes P.J. Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease. Eur. Respir. J. 2007; 29: 1224–1238.Smeeth L., Thomas S.L., Hall A.J. et al. Risk of myocardial infarction and stroke after acute infection or vaccination. N. Engl. J. Med. 2004; 351: 2611–2618.Smeeth L., Thomas S.L., Hall A.J. et al. Risk of myocardial infarction and stroke after acute infection or vaccination. N. Engl. J. Med. 2004; 351: 2611–2618.Seneff M.G., Wagner D.P., Wagner R.P. et al. Hospital and 1-year survival of patients admitted to intensive care units with acute exacerbation of chronic obstructive pulmonary disease. J.A.M.A. 1995; 274: 1852–1857.Seneff M.G., Wagner D.P., Wagner R.P. et al. Hospital and 1-year survival of patients admitted to intensive care units with acute exacerbation of chronic obstructive pulmonary disease. J.A.M.A. 1995; 274: 1852–1857.Zielinski J., MacNee W., Wedzicha J. et al. Causes of death in patients with COPD and chronic respiratory failure. Monaldi Arch. Chest Dis. 1997; 52: 43–47.Zielinski J., MacNee W., Wedzicha J. et al. Causes of death in patients with COPD and chronic respiratory failure. Monaldi Arch. Chest Dis. 1997; 52: 43–47.Parker C.M., Voduc N., Aaron S.D. et al. Physiological changes during symptom recovery from moderate exacerbations of COPD. Eur. Respir. J. 2005; 26: 420–428.Parker C.M., Voduc N., Aaron S.D. et al. Physiological changes during symptom recovery from moderate exacerbations of COPD. Eur. Respir. J. 2005; 26: 420–428.Anthonisen N.R., Manfreda J., Warren C.P. et al. Antibiotic therapy in exacerbations of chronic obstructive pulmonary disease. Ann. Intern. Med. 1987; 106: 196–204.Anthonisen N.R., Manfreda J., Warren C.P. et al. Antibiotic therapy in exacerbations of chronic obstructive pulmonary disease. Ann. Intern. Med. 1987; 106: 196–204.Spencer S., Jones P.W., GLOBE Study Group. Time course of recovery of health status following an infective exacerbation of chronic bronchitis. Thorax 2003; 58: 589–593.Spencer S., Jones P.W., GLOBE Study Group. Time course of recovery of health status following an infective exacerbation of chronic bronchitis. Thorax 2003; 58: 589–593.Gross N.J., Bankwala Z. Effects of an anticholinergic bronchodilator on arterial blood gases of hypoxemic patients with chronic obstructive pulmonary disease, comparison with a beta-adrenergic agent. Am. Rev. Respir. Dis. 1987; 136: 1091–1094.Gross N.J., Bankwala Z. Effects of an anticholinergic bronchodilator on arterial blood gases of hypoxemic patients with chronic obstructive pulmonary disease, comparison with a beta-adrenergic agent. Am. Rev. Respir. Dis. 1987; 136: 1091–1094.Karpel J.P. The use of anticholinergic drugs in acute exacerbations of chronic obstructive pulmonary disease. In: Gross N.J., ed. Anticholinergic therapy in obstructive airways disease. London: Franklin Scientic Publications; 1993. 145–154.Karpel J.P. The use of anticholinergic drugs in acute exacerbations of chronic obstructive pulmonary disease. In: Gross N.J., ed. Anticholinergic therapy in obstructive airways disease. London: Franklin Scientic Publications; 1993. 145–154.Fernandez A., Muñoz J., Calle B. et al. Comparison of one versus two bronchodilators in ventilated COPD patients. Int. Care Med. 1994; 20: 199–202.Fernandez A., Muñoz J., Calle B. et al. Comparison of one versus two bronchodilators in ventilated COPD patients. Int. Care Med. 1994; 20: 199–202.O'Driscoll B.R., Taylor R.J., Horsley M.G. et al. Nebulized salbutamol with and without ipratropium bromide in acute airflow obstruction. Lancet 1989; 2: 1418–1420.O'Driscoll B.R., Taylor R.J., Horsley M.G. et al. Nebulized salbutamol with and without ipratropium bromide in acute airflow obstruction. Lancet 1989; 2: 1418–1420.Boe J., Dennis J.H., O'Driscoll B.R. et al. European Respiratory Society Guidelines on the use of nebulizers. Eur. Respir. J. 2001; 18: 228–242.Boe J., Dennis J.H., O'Driscoll B.R. et al. European Respiratory Society Guidelines on the use of nebulizers. Eur. Respir. J. 2001; 18: 228–242.Авдеев С.Н., Нуралиева Г.С., Батын С.З. и др. Эффективность комбинированной терапии ингаляционными β2-агонистами и антихолинергическими препаратами при тяжелом обострении хронической обструктивной болезни легких: рандомизированное контролируемое исследование. Пульмонология 2007; 3: 56–65.Авдеев С.Н., Нуралиева Г.С., Батын С.З. и др. Эффективность комбинированной терапии ингаляционными β2-агонистами и антихолинергическими препаратами при тяжелом обострении хронической обструктивной болезни легких: рандомизированное контролируемое исследование. Пульмонология 2007; 3: 56–65.Bach P.B., Brown C., Gelfand S.E., McCrory D.C. Management of acute exacerbations of chronic obstructive pulmonary disease: a summary and appraisal of published evidence. Ann. Intern. Med. 2001; 134: 600–620.Bach P.B., Brown C., Gelfand S.E., McCrory D.C. Management of acute exacerbations of chronic obstructive pulmonary disease: a summary and appraisal of published evidence. Ann. Intern. Med. 2001; 134: 600–620.Авдеев С.Н. Небулайзерная терапия обструктивных заболеваний легких. Consilium Medicum 2011; 13 (3): 36–43.Авдеев С.Н. Небулайзерная терапия обструктивных заболеваний легких. Consilium Medicum 2011; 13 (3): 36–43.Willaert W., Daenen M., Bornans P. et al. What is the optimal treatment strategy for chronic obstructive pulmonary disease exacerbations? Eur. Respir. J. 2002; 19: 928–935.Willaert W., Daenen M., Bornans P. et al. What is the optimal treatment strategy for chronic obstructive pulmonary disease exacerbations? Eur. Respir. J. 2002; 19: 928–935.Guerin C., Chevre A., Dessirier P. et al. Inhaled fenoterolipratropium bromide in mechanically ventilated patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 1999; 159: 1036–1042.Guerin C., Chevre A., Dessirier P. et al. Inhaled fenoterolipratropium bromide in mechanically ventilated patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 1999; 159: 1036–1042.

The authors declare that there are no conflicts of interest present.